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Covid-19 treatment Paxlovid can interact with common heart medications, doctors warn
cnn ^ | 10/12/2022 | jacquelaine howard

Posted on 10/13/2022 9:43:12 AM PDT by bitt

Covid-19 patients with a history of cardiovascular disease are at an increased risk of developing severe illness and could benefit most from the Covid-19 treatment Paxlovid – but there’s a catch.

Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease, including certain statins and heart failure therapies, a new paper warns.

The review paper, published Wednesday in the Journal of the American College of Cardiology, lists dozens of cardiovascular medications and whether they are safe to give along with Paxlovid or whether they could have interactions.

Some medications such as aspirin are safe to take with Paxlovid, according to the paper, but other drugs could have interactions, and therefore, their dosage should be adjusted or temporarily discontinued while a patient is taking Paxlovid.

When President Joe Biden tested positive for Covid-19 and started Paxlovid in July, his physician Dr. Kevin O’Connor temporarily took him off Crestor and Eliquis, two heart medications that the President takes for his pre-existing conditions. Doctors say there is no short-term risk to stopping these drugs.

The review paper says that interactions between Paxlovid and certain blood thinners can cause an increased risk of bleeding. Interactions between Paxlovid and some cholesterol medications such as statins can be toxic to the liver, and interactions between Paxlovid and certain blood pressure medications could cause low blood pressure, flushing and swelling.

(Excerpt) Read more at cnn.com ...


TOPICS:
KEYWORDS: adverse; bpmeds; contraindications; covid; crestor; eliquis; heartmeds; paxlovid; paxlovidinteractions; statins; vaccine; vaccines; vaers; whoops
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1 posted on 10/13/2022 9:43:12 AM PDT by bitt
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To: null and void; aragorn; EnigmaticAnomaly; kalee; Kale; AZ .44 MAG; Baynative; bgill; bitt; ...

p


2 posted on 10/13/2022 9:43:25 AM PDT by bitt (<IMG SRC=' 'width=50%>)
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To: bitt
When President Joe Biden tested positive for Covid-19 and started Paxlovid in July, his physician Dr. Kevin O’Connor temporarily took him off Crestor and Eliquis, two heart medications that the President takes for his pre-existing conditions. Doctors say there is no short-term risk to stopping these drugs.

Really?

Then why take them at all?

3 posted on 10/13/2022 9:47:26 AM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: Vendome

Except for the risk of stroke after stopping a blood-thinner suddenly. I know someone who was ordered to stop taking Eliquis ‘cold-turkey’ by a doctor. He had a stroke within 48 hours and died of a clot in his brain stem.


4 posted on 10/13/2022 9:59:06 AM PDT by jps098
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To: bitt

More “good news”...


5 posted on 10/13/2022 10:09:14 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: Vendome

“Then why take them at all?”

That would be a long-term risk.


6 posted on 10/13/2022 10:10:01 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: Carriage Hill

Shudup.../S


7 posted on 10/13/2022 10:17:47 AM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: Vendome
”Doctors say there is no short-term risk to stopping these drugs.”

The doctors should have said, “There is extremely low risk to stopping these drugs.”

Many interactions are caused by the fact that several medications are metabolized by the same enzymes in the body. Introducing a second drug which depends upon a given enzyme reduces the level of enzyme available for metabolizing the first drug.

Failure to be metabolized and removed from the body can cause the dosage in the blood to increase as if a higher amount of the drug had been taken.

My wife was recently given Paxlovid. Her blood pressure medication was reduced to one half the usual amount. Due to the expected slowing of the metabolizing of the blood pressure medication, it was expected that the level in her blood would increase maintaining the effectiveness of the drug.

I was considered for Paxlovid but wasn’t prescribed because I take a complicated array of drugs and that made management in the presence of Paxlovid too uncertain. If I had had more symptoms of Covid the decision might have been different.

8 posted on 10/13/2022 10:19:42 AM PDT by William Tell
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To: bitt

Gotta love EUAs. My expectation is that these side effects are found before releasing it to the general populace.


9 posted on 10/13/2022 10:20:00 AM PDT by fretzer
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To: William Tell

I took Paxlovid and my doc did the same thing (short term cessation of Crestor). Frankly, I didn’t notice that it did any good (it still felt like the flu for 3 days and was then gone), but the Paxlovid has a side effect that makes your mouth taste like you swallowed a large bag of trash. Just gross.


10 posted on 10/13/2022 10:28:31 AM PDT by jagusafr ( )
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To: bitt; Albion Wilde; Kathy in Alaska; mosaicwolf; Red Badger; Tilted Irish Kilt; John S Mosby; ...

A direct report to my daughter was given Paxlovid by her physician because this woman supposedly had Covid and has diabetes. After taking Paxlovid, this woman is having to use a walker and can barely see. There was a period of time where she could not walk at all. Currently, they have no idea if this is for life.

Beware of Paxlovid.


11 posted on 10/13/2022 11:12:26 AM PDT by ExTexasRedhead
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To: Vendome

(((...Heh...)))


12 posted on 10/13/2022 11:23:52 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: bitt; 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...
Infectious Disease ping - Covid medication, Paxlovid, may interfere with other cardiovascular medications
See the news article for a list of prescribed medications that could cause adverse reactions, including certain statins and other heart failure therapies (Emphasis Mine)

" Covid-19 patients with a history of cardiovascular disease are at an increased risk of developing severe illness
and could benefit most from the Covid-19 treatment Paxlovid – but there’s a catch.
Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease,
including certain statins and heart failure therapies, a new paper warns.
The review paper, published Wednesday in the Journal of the American College of Cardiology, lists dozens of cardiovascular medications
and whether they are safe to give along with Paxlovid or whether they could have interactions.

Some medications such as aspirin are safe to take with Paxlovid, according to the paper, but other drugs could have interactions, and therefore,
their dosage should be adjusted or temporarily discontinued while a patient is taking Paxlovid."

13 posted on 10/13/2022 11:53:08 AM PDT by Tilted Irish Kilt
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To: Tilted Irish Kilt

Bttt


14 posted on 10/13/2022 12:07:38 PM PDT by Guenevere (“If the foundations are destroyed, what can the righteous do?”)
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To: William Tell

Don’t forget the effects of grapefruit juice in this regard.
Seriously.


15 posted on 10/13/2022 12:30:01 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: Vendome

Crestor is to prevent early heart attack maybe due to high cholesterol.

Joe is either in his 80’s or close to them. So he is past the age for an early heart attack. Taking a Statin/Crestor at his age or my age is not really a wise move.

You are never too old to have a stroke. I’m on Eliquis 2x a day, and I don’t like not taking it. Strokes contributed to the death of my maternal granddad and his daughter, my mother.


16 posted on 10/13/2022 12:37:00 PM PDT by Grampa Dave ( Anyone, who can make you believe in absurdities, can make you commit atrocities!!" ~ (Voltaire)!, )
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To: Grampa Dave

My physician, at my request, reduced my Eliquis in half because I am now taking so many supplements that thin the blood.

She agreed.


17 posted on 10/13/2022 1:50:50 PM PDT by Karoo
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To: Karoo

That sounds like a good MD who listens to their patients.

That is a winning combo for the MD and patient!)


18 posted on 10/13/2022 2:21:40 PM PDT by Grampa Dave ( Anyone, who can make you believe in absurdities, can make you commit atrocities!!" ~ (Voltaire)!, )
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To: Karoo

That sounds like a good MD who listens to their patients.

That is a winning combo for the MD and patient!)


19 posted on 10/13/2022 2:22:10 PM PDT by Grampa Dave ( Anyone, who can make you believe in absurdities, can make you commit atrocities!!" ~ (Voltaire)!, )
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To: jagusafr
"... but the Paxlovid has a side effect that makes your mouth taste like you swallowed a large bag of trash."

My wife said she got a very bitter taste. She overcame it by sucking on very strong cough drops.

20 posted on 10/13/2022 2:54:01 PM PDT by William Tell
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