Posted on 06/06/2021 2:56:32 PM PDT by Fractal Trader
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One drug that has attracted interest is the antiparasitic compound ivermectin, a macrocyclic lactone derived from the bacterium Streptomyces avermitilis. We carried out a docking study to determine if ivermectin might be able to attach to the SARS-CoV-2 spike receptor-binding domain bound with ACE2. Materials and methods: We used the program AutoDock Vina Extended to perform the docking study. Results: Ivermectin docked in the region of leucine 91 of the spike and histidine 378 of the ACE2 receptor. The binding energy of ivermectin to the spike-ACE2 complex was -18 kcal/mol and binding constant was 5.8 e-08. Conclusion: The ivermectin docking we identified may interfere with the attachment of the spike to the human cell membrane. Clinical trials now underway should determine whether ivermectin is an effective treatment for SARS-Cov2 infection.
(Excerpt) Read more at researchgate.net ...
bkmrk
Did you get Covid and use Ivermectin to help with it?
No, we have not had Covid.
“that was a typo ...12-24 mg”
I know, I was having some fun with it!
It's milligrams (mg) not grams.
” It’s milligrams (mg) not grams. “
yep ... i’ve posted the correction about six different times now ...
“Ignore cantnipman’s suggestions for dosing. They are entirely wrong, by a factor of 1000. He has confused milligrams with grams.”
typo ... supposed to have been mg ... posted correction about 10 different times now ... seems not to matter though ...
“your dosing is totally incorrect”
yep ... type ... supposed to have been mg ... this makes 11 times that i’ve now noted that correction ...
Did you know your dosing amount was off?
😂
Than You for pointing out the dosage error.
This is why they don’t want people self medicating. Their math is horrible.
All a person needs to do is step back and use common sense as a reasonableness test. Would a human dosage be greater than a horse dosage? I doubt it.
Neither have I. I don’t want the vax, just want to know the best way to deal with Covid if I did happen to get it, to be prepared to ward off the storm with the best treatment. Ivermectin sounds promising, just looking for real life examples of people who have used it succesfully. I do have some friends who had it last fall, and used hydroxycloriquine, with zinc and vitamin D. They got better, seemingly not harmed by the disease.
“Now where can one buy the REAL IVERMECTIN FOR HUMANS?
Or alternatively, what’s the safe recipe for making it?”
Well, you fly to Japan and take a soil sample from a golf course near the southeast coast of Honshu. Isolate an unusual Streptomyces bacterium, Streptomyces avermectins, from the soil that cures mice with roundworm infections. Grow the bacterium in a bioreactor at 25 degrees centigrade at a pH of 8.5. Isolate and purify the metabolic extracts. That will give you the precursor for ivermectin
No need to travel to Japan, soil fermentation products Streptomyces avermitilis, a soil actinomycete will replicate beneficial effects.
https://pubmed.ncbi.nlm.nih.gov/26752081/
The more I read, the more it seems Ivermectin for humans should be taken for 2 days per month as a general parasitic cleaning regimen for the internal body, the side effects appear to be nil to zero.
Right now, in tablet form it appears to be sold out everywhere.
“Did you know your dosing amount was off?”
did you see my subsequent DOZEN acknowledgements that gram was a type for mg?
And it should also be noted that the co-discoverers of Ivermectin were awarded the Nobel Prize in Medicine for it.
That’s not something you get for discovering a dog wormer.
ping
I agree the cat... dose is way too high. I don’t have time to search for the research paper I read a few weeks ago. However I think various studies were using ,2 or ,02 mg./kg or .4 to .04 mg/kg for humans. I don’t remember where the decimal. In earlier FR posts it was said that a dose for a 1200 lb horse could be divided inro 8 to 12 doses depending on the weight of a human.
according to the article a soil sample from a golf course near the southeast coast of Honshu is the only place found to have the right strain of Streptomyces. I am sure you can buy that strain on the open market today. Interesting that all kinds of anti viral anti fungal anti bacterial anti inflammatory byproducts are being found in a humble soil bacteria
Is this the one who called it the "Ivermectin hoax"?
Hint. Mexico.
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