Drag and friction can be ameliorated by using a laser to create a plasma in front of a projectile, reducing resistance and therefore drag for the missile to travel through.
Powered by the energy produced by the rocket motor, it is achievable. Don’t ask how I know....
How do you know? Are you a fan of Leik Maraibo? How about Paul La Violette?
Naw... there's much better ways.
First, you need ion propulsion to generate a sub-space warp field and using sequenced teleported deflector shields to prevent drag on plasma projectiles, accuracy is guaranteed by locking in teleportation coordinates and then beaming up Scotty to keep him out of the way.