Posted on 05/27/2020 8:54:50 AM PDT by SeekAndFind
Dr. Anthony Fauci on Wednesday said there's no evidence that shows the anti-malaria drug hydroxychloroquine is effective at treating COVID-19.
"Clearly the scientific data is really quite evident now about the lack of efficacy for it," Fauci, the nation's top infectious disease doctor, said during a CNN interview.
Fauci said evidence also shows the likelihood that the drug can cause severe irregular heart rhythms.
"There was suspicion of that for a while, but as data comes in, it becomes more clear," Fauci said.
The pronouncements mark Fauci's strongest warnings yet against the drug and puts him at odds with President Trump, who has embraced the drug as a "game changer" and a "miracle."
Earlier this month, Trump even said he had been taking hydroxychloroquine, in combination with zinc, as a way to prevent getting COVID-19, the disease caused by the novel coronavirus. He called the research on hospitalized patients “a Trump enemy statement.”
“I think it gives you an additional level of safety,” Trump said at the time, downplaying warnings that the drug can cause heart problems in certain patients.
To date, Fauci has told Americans not to assume the drug could be a "knockout" against the virus, because the clinical evidence on the effectiveness of hydroxychloroquine was lacking.
Earlier this month, the National Institute of Allergy and Infectious Diseases, which Fauci leads, announced a 2,000-patient study to determine whether hydroxychloroquine, when combined with the antibiotic azithromycin, “can prevent hospitalization and death from COVID-19."
"Although there is anecdotal evidence that hydroxychloroquine and azithromycin may benefit people with COVID-19, we need solid data from a large randomized, controlled clinical trial,” Fauci said in a statement announcing the trial.
(Excerpt) Read more at thehill.com ...
On the same day Fauci condemns it when France’ (and ours) own medical doctors not only support it but claim they’re seeing results in practice?
That’s political - not science.
They will use use this very flawed study to shutdown any type of RCT,and any type of research into HCQ. Basically declared it deadly by lying with statistic
Data shows no evidence of Fauci ever being right about anything
I saw that. I take is Dr. Raoult is overruled.
If you understand French this will make you happy. Professor Raoult tells about lessons learned from the pandemic. One lesson is that zinc is important. People with low zinc levels fare much worse.
https://www.mediterranee-infection.com/4000-patients-traites-vs-big-data-qui-croire/
This disease is not going to kill 99.2 out of every 100 people that get it.
I laugh at the HCQ nuts on here that are so invested in its success because Trump talked about it that they dismiss credible tests; they dismiss the information that the end results are negligible; and they want to take a prescription drug without advice of doctors.
If we were talking about any other drug, in any other context, none of you would give a shit. And you don’t realize how silly this makes you all appear.
Lies again, the president didn’t say the drug WAS a game-changer, he said we needed to study it to see if it COULD BE.
We studied it, unfortunately it took WAY TOO LONG because of politics, but that is what Trump wanted, for studies to look at it and see if it was helpful.
It isn’t used for respiratory illness, it is used for Malaria and Lupus. It primarily suppresses immune systems, which means it might have been helpful for cases where immune systems went crazy, but we have other treatments for that as well. ANd it seemed possible it helped with zinc intake, and that zinc intake might be important, but for some reason that doesn’t seem to be much of what was studied when the drug was studied.
On the other hand, we are now learning that pretty much ANY treatment by competent medical workers gives 99% treatment success.
When you are not already dying, and you get appropriate medical care, you beat this thing, in almost every case. Hospitalizations are down, deaths are down, incubator use is down. We have largely made this into a severe flu, but we are still treating it like it kills 3% of the people, when CDC now admits it kills maybe 0.3%, and that is because too many nursing homes are still getting infected.
“India loves it. https://www.scmp.com/week-asia/health-environment/article/3086389/coronavirus-india-invites-scepticism-it-sticks
Africa, too.”
Exactly. Across Europe too.
RE: We studied it, unfortunately it took WAY TOO LONG because of politics
Depends on the KIND of study made. I’m still waiting for studies that attempt to REPLICATE the many successful treatments made by physicians in the USA and in other countries.
Unless one wants to believe that all these physicians are lying, then I can’t believe an ADEQUATE study has been made.
RE: If you understand French this will make you happy. Professor Raoult tells about lessons learned from the pandemic. One lesson is that zinc is important. People with low zinc levels fare much worse.
Gosh, I wish there were English subtitles to this interview.
Quit asking this bassturd anything. Pence should silence him.
Fauci: there is no evidence that the sky is blue! *eyes crossed*
Then Fraudci is a liar, a horse’s ass or a paid agent for the DNC. I’m sick of this lying little weasel.
I agree. Unfortunately I haven’t time to try and translate the whole interview but beginning minute 2:50 he says:
We have collected lots of measurements, probably a unique collection of cases, and we now know things that have been underestimated, like, for instance, the fact that zinc plays a role regarding the severity of the pathology; patients with the most serious disease have the lowest zinc concentrations.
Or to be more exact...lower zinc than the others.
/SB
Fauchi is so full of s**t, it is coming out his ears.
[This disease is not going to kill 99.2 out of every 100 people that get it.]
https://www.worldometers.info/coronavirus/country/us
I’m completely uninvested in quinine’s success. I would not be surprised if it turned out to be a dud. I know someone who was on it for this virus, and died anyway, while hooked up to a ventilator. The guy worked for a very well-known, globally-recognized company in the tri-state area and had a great health plan.
But the backward-looking studies aren’t clinical trials. Lot of cherry-picking involved. The moment Trump’s name became associated with this drug, it was off to the races in terms of ways to sling mud at it. I would not be surprised if ideologically-motivated researchers picked out only the cases that advanced their preferred anti-Trump narrative. Wouldn’t be the first time, and won’t be the last.
https://www.mediterranee-infection.com/early-diagnosis-and-management-of-covid-19-patients-a-real-life-cohort-study-of-3737-patients-marseille-france/
COVID-IHU #15
Version 1 du 27 Mai 2020 Early diagnosis and management of COVID-19 patients: a real-life cohort study of 3,737 patients, Marseille, France
Abstract
Background: In our institute in Marseille, France, we proposed early and massive screening for coronavirus disease 2019 (COVID-19). Hospitalization and early treatment with hydroxychloroquine and azithromycin (HCQ-AZ) was proposed for the positive cases.
Methods:
We retrospectively report the clinical management of 3,737 patients, including 3,054 (81.7%) treated with HCQ-AZ for at least three days and 683 (18.3%) patients treated with other methods (“others”). Outcomes were death, transfer to the intensive care unit (ICU), ≥10 days of hospitalization and viral shedding.
Results:
By testing 101,522 samples by polymerase chain reaction (PCR) from 65,993 individuals, we diagnosed 6,836 patients (10.4%), including 3,737 included in our cohort. The mean age was 45 (sd 17) years, 45% were male, and the fatality rate was 0.9%. We performed 2,065 low-dose computed tomography (CT) scans highlighting lung lesions in 581 of the 933 (62%) patients with minimal clinical symptoms (NEWS score = 0). A discrepancy between spontaneous dyspnoea, hypoxemia and lung lesions was observed. Clinical factors (age, comorbidities, NEWS-2 score), biological factors (lymphopenia; eosinopenia; decrease in blood zinc; and increase in D-dimers, lactate dehydrogenase (LDH), creatinine phosphokinase (CPK), and c-reactive protein (CRP)) and moderate and severe lesions detected in low-dose CT scans were associated with poor clinical outcome. Treatment with HCQ-AZ was associated with a decreased risk of transfer to the ICU or death (HR 0.19 0.12-0.29), decreased risk of hospitalization ≥10 days (odds ratios 95% CI 0.37 0.26-0.51) and shorter duration of viral shedding (time to negative PCR: HR 1.27 1.16-1.39).
QTc prolongation (>60 ms) was observed in 25 patients (0.67%) leading to the cessation of treatment in 3 cases. No cases of torsade de pointe or sudden death were observed.
Conclusion
Early diagnosis, early isolation and early treatment with at least 3 days of HCQ-AZ result in a significantly better clinical outcome and contagiosity in patients with COVID-19 than other treatments. Long-term follow-up to screen for fibrosis will be the next challenge in the management of COVID-19.
My (SB) comments: Note, the mortality is for the total cohort. The mortality of those patients receiving HCQ+AZ(+Zn) is according to their webpage presently 18/3318 = 0.54%. (The webpage just went down. Lots of people wanting to read, or a DDoS attack?)
Two things will happen: 1) no msm will ever talk about it until 2) someone writes a "devastating" critique, and then that is all anyone will hear.
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