Posted on 02/16/2020 9:15:58 PM PST by Bon mots
What is your risk to get infected coronavirus?
East Asians, Japanese, and Han Chinese are the most likely people to become severely sick by the coronavirus with a chance of more than 90% when exposed. Europeans only rank in the 50%, Africans in the 60% range, and considered low to medium. It also makes a difference if one is a smoker or non-smoker.
The Travel and Tourism industry is in turmoil. Tourism leaders don’t want anyone to panic, but the story doesn’t yet have an end to it.
At the same time, researchers are working around the clock to learn more about the deadly virus. Recent studies may explain why Europe, America had no deadly cases of the virus, and no coronavirus cases at all were reported from Africa.
Stopping travel may not be the solution and could only mean travel businesses could become collateral damage in the fight against coronavirus. The World Health Organization always said “do not stop travel and commerce.”, even after WHO declared a global epidemic emergency.
Why is this?
The novel coronavirus (2019-nCov) was identified in Wuhan, Hubei Province, China in December of 2019.
This new coronavirus has resulted in thousands of cases of lethal disease in China, with additional patients being identified in a rapidly growing number internationally.
2019-nCov was reported to share the same receptor, Angiotensin-converting enzyme 2 (ACE2), with SARS-Cov.
Here based on the public database and the state-of-the-art single-cell RNA-Seq technique, the ACE2 RNA expression profile in the normal human lungs. The result indicates that the ACE2 virus receptor expression is concentrated in a small population of type II alveolar cells (AT2).
Surprisingly, studies found that this population of ACE2-expressing AT2 also highly expressed many other genes that positively regulating viral reproduction and transmission.
A comparison between eight individual samples demonstrated that the Asian male one has an extremely large number of ACE2-expressing cells in the lung. This is based on an unfinished study by Yu Zhao, Zixian Zhao, Yujia Wang, Yueqing Zhou, Yu Ma, Wei Zuo and published by Bio Rxiv:
A second study investigates how and why the virus will enter the human body, by Michael Letko, Vincent Munster
Apparently the coronavirus enters a human body through some connection with something called the ACE2 receptor. East Asians and men have more than say white Europeans and women. Being a white woman seems to be the way to have much lesser risk.
According to this study and based on the assumption in this study and in regards to the receptor, Angiotensin-converting enzyme 2, human populations where samples were available were categorized by risk in obtaining a dangerous version of the virus. Most ill may not feel more than a common cold, for others Coronavirus can be fatal.
According to this preliminary study the risk of obtaining the virus:
High risk 90%-99%
Japanese in Tokyo, Japan
Southern Han Chinese
Kinh in Ho Chi Minh City, Vietnam
Han Chinese in Bejing, China
Chinese Dai in Xishuangbanna, China
Moderate Risk: 80-89%
Not found
Medium to Moderate Risk: 70-79%
Peruvians from Lima, Peru
Bengali from Bangladesh
Sri Lankan Tamil from the UK
Indian Telgu from the UK
Mexican Ancestry from Los Angeles, USA
South Asians (general average)
Medium Risk: 60-69%
Gujarati Indians from Houston, TX
Admixed Americans
Americans of African Ancestry in SW USA
Punjabi from Lahore, Pakistan
African Caribbeans in Barbados
Luhya in Webuye, Kenya
Mende in Sierra Leona
Africans (general average)
Esan in Nigeria
British in U.K.
Gambians in Western Division in The Gambia
Puerto Ricans
Low to Medium Risk: 50-59%
Colombians from Medellin
Yoruba in Ibadan, Nigeria
Finnish in Finland
Iberian Population in Spain
Europeans (in General)
Utah Residence (Caucasians)
Toscani, Italy
Now that's funny, folks. [/cableguy]
Does this mean that ACE2 inhibitor might be useful?
Do they block the ACE2 receptor?
Chinese women smoke?
(where?)
Are you sure?
US media will do their damnest to not report about a Yellow Virus.
Cool! All those mannish-looking “women” beating the feminine-looking women aren’t going to get sick.
Doubt it. Same group in the USA probably picked up the practices of using indoor toilets and washing their hands, at least to enough of a degree to affect the odds.
The one child policy produced to many butter balls. China is culling the herd
Best information I have seen about this.
I think co-morbidity, had it been put to the test, is a Venn overlap with Chinese malnutrition.
Location is simply based on the donor population that was tested "human populations where samples were available".
More like “kills people who are most likely to smoke and/or breathe in highly polluted air.” Smoking is more or less on the way out in most other parts of the world.
If you do not smoke and have never lived in a city with poor, smoggy air, you are more likely to survive this or other illnesses that cause respiratory problems. Me, I lived in smoggy LA as a kid and I’m *still* down some 30% or so of lung capacity - and I never smoked. Asian city smokers can be down as much as 60% or more of lung function.
Urban Indians didn’t have that problem, but it should be pointed out that smoking is frowned upon in public in most US cities’ social establishments and in society as a whole these days, unlike India. And, as opposed to Indian city air, Houston’s level of pollution is faaaaaaar less and therefore less damaging to lung function.
He certainly won't inhale any virus into his lungs.
My wife is worried. She doesn't smoke, never did. But her father smoked a lot every day, especially cigars, so she was exposed to a lot of second-hand smoke. She's Chinese-American, and has had multiple cancers so has weak immunity due to chemo and radiation treatments. We're watching this outbreak closely. We're here in the SF Bay Area so it's a major transportation node to Asia. We were in a church this weekend and a kid was coughing behind her, annoyed her greatly. Hopefully this virus will end soon and we can all breathe easier (literally).
I don't think even the PRC would be dumb enough to believe that it would not get back to the mainland from Taiwan.
It would be best to stay away from crowds if at all possible until this virus runs its course.
I have zero qualms, about leaving anyplace someone coughs.
I am out of there. To another seat, outside or just leaving.
For the duration of this, that is me.
This does not mean the Mormons will take over the world...Bring Out Your Dead
Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.
The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.
So far the false positive rate is 100%.
At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.
*sigh* Such is life, and death...
If a quarantine saves just one child's life, it's worth it.
My guess is that Utah is on list due to Lds missionaries around the world: They only spend 2 yrs in the field & around half of them are returning home in 2020...not just to Utah but predominately Utah.
Dunno. How many 7-11s can a city have?
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