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No, the 2019-nCoV [coronavirus] genome doesn’t really seem engineered from HIV
The Prepared ^ | 1/31/2020 | Ari Allyn-Feuer

Posted on 01/31/2020 8:50:37 PM PST by catnipman

They found that all four of these spike protein inserts appear as matches to at least one sequence in at least one variant of the HIV virus. The sequences come from the gp120 and Gag proteins in HIV, the former of which is also a viral envelope recognition protein. This has led many to credulously assume that this is evidence, or even a strong indication, that 2019-nCoV was engineered from its bat ancestor by humans inserting HIV sequences.

But they’re wrong; it’s still not engineered. An analysis of the paper clearly reveals that:

1. There is nothing remarkable about the fact that 2019-nCoV’s sequence diverges from its nearest known relative, or that its unique sequences are conserved among cases of 2019-nCoV.

2. The sequence matches with HIV are very short and appear in hypervariable regions of both virus, and similar overlaps are seen between 2019-nCoV sequences and many other organisms.

3. The unique biological properties that HIV sequences could theoretically impart to another virus are completely missing from 2019-nCoV, and 2019-nCoV has no unique clinical properties that are outside what is known to be possible for a coronavirus.

In other words, the sequence overlap is not actually uncanny, and there is no big scoop here. The group in India fell prey to some of the pitfalls of bioinformatics research.

The 2019-nCoV genome does not contain remarkable genomic properties which need explaining, and for which we’d look to some kind of bioengineering as a cause.

2019-nCoV continues to give every appearance of being a wild coronavirus that jumped from bats to humans by way of an animal intermediary in the Huanan seafood market in Wuhan in late 2019.

(Excerpt) Read more at theprepared.com ...


TOPICS: Culture/Society; Foreign Affairs; News/Current Events
KEYWORDS: 2019ncov; coronavirus; deepstatevirus; gaslight; hiv; militarygrade; pandemic; weaponized
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To: Black Agnes
These aren’t molecular modelers…..They’re looking at the 2D representation of this protein…..The 3D is convincing…..All but one of these insertions are in the ‘fingertip’ region of this protein….. And the idea that you’d have any number of significant insertions and end up with a gain of function mutant is dodgy itself.

https://twitter.com/trvrb/status/1223666856923291648

BTW – the authors of this preprint posted this today:

Prashant Pradhan • 6 hours ago

This is a preliminary study. Considering the grave situation, it was shared in BioRxiv as soon as possible to have creative discussion on the fast evolution of SARS-like corona viruses. It was not our intention to feed into the conspiracy theories and no such claims are made here. While we appreciate the criticisms and comments provided by scientific colleagues at BioRxiv forum and elsewhere, the story has been differently interpreted and shared by social media and news platforms. We have positively received all criticisms and comments. To avoid further misinterpretation and confusions world-over, we have decided to withdraw the current version of the preprint and will get back with a revised version after reanalysis, addressing the comments and concerns. Thank you to all who contributed in this open-review process.

: Authors of the Manuscript

Scientists, especially the younger ones, use ‘unscientific’ terms all the time. Once us old farts die off, who knows what will appear in professional journals...it will be the end of the world, i’m sure.

“This virus is like totally woke and lit, I can't even, and be salty AF when you trolls and your white privilege peer review clap back, because like brah - duh?” Said no one ever in a serious scientific paper. YMMV : ),

221 posted on 02/01/2020 4:11:41 PM PST by MD Expat in PA (No. I am not a doctor nor have I ever played one on TV. The MD in my screen name stands for Maryland)
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To: Spktyr

Are HIV meds currently used for anything else?


222 posted on 02/01/2020 4:11:52 PM PST by HollyB
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To: MD Expat in PA

If you don’t think the Chicoms control sci-tech these days you’ve not been paying attention.

someone pulled their chain.

i can tell you that in the back channel stuff everyone is freaking out still.


223 posted on 02/01/2020 4:13:55 PM PST by Black Agnes
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To: Swordmaker
A few of years ago, a study of scientific and scholarly papers was done of papers published in various peer-reviewed journals was undertaken and it discovered that an amazingly high percentage of them were bogus, and the peer-reviews were bogus as well!

I recall that some of these investigators succeeded in getting some totally made up papers accepted by journals that were completely bogus, and even got them peer-reviewed and published, before they revealed the absurdities of their papers.

Yes. But the latter ones I recall were in “soft sciences” - sociology journals and were purposely bogus to make a point.

https://phys.org/news/2018-10-real-fake-hoodwinks-journals.html

But it is also a problem in other journals as you pointed out and as discussed here:

https://www.enago.com/academy/retractions-due-to-fake-peer-reviews/

The bottom line is that especially for us non-scientists, we should be skeptical of articles in the MSM with headlines like “A recent study proves…”

224 posted on 02/01/2020 4:26:59 PM PST by MD Expat in PA (No. I am not a doctor nor have I ever played one on TV. The MD in my screen name stands for Maryland)
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To: Black Agnes
If you don’t think the Chicoms control sci-tech these days you’ve not been paying attention. someone pulled their chain.

No. The people who pulled their chain in the comments section of their preprint, are not Chicoms but scientists who questioned and tried to replicate their results using the same methods or had looked at the same data and came to much different conclusions.

i can tell you that in the back channel stuff everyone is freaking out still.

And what sort of "back channel stuff" do you have access to that othera, especially scientists in the field do not?

225 posted on 02/01/2020 4:35:08 PM PST by MD Expat in PA (No. I am not a doctor nor have I ever played one on TV. The MD in my screen name stands for Maryland)
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To: HollyB

Yes! Ritonavir is used to treat hepatitis C and lopinavir is used to treat human papilloma virus, to name some on-label uses.


226 posted on 02/01/2020 4:38:39 PM PST by Spktyr (Overwhelmingly superior firepower and the willingness to use it is the only proven peace solution.)
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To: Bommer
From 2003 - Cloaked similarity between HIV-1 and SARS-CoV suggests an anti-SARS strategy

https://link.springer.com/article/10.1186/1471-2180-3-20

227 posted on 02/01/2020 4:41:06 PM PST by MD Expat in PA (No. I am not a doctor nor have I ever played one on TV. The MD in my screen name stands for Maryland)
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To: Swordmaker
“Author’s note: I have a Ph.D. in bioinformatics, and am a principal data scientist at a major pharmaceutical company. This paper isn’t directly in my wheelhouse, but it’s pretty close.”

Translation: he’s a computer nerd with a special emphasis in biology data, not anything having to do with virology. He’s blowing smoke screens about his expertise and his alphabet soup behind his name.

It should be noted that the authors of this preprint paper are also in bioinformatics but unlike Ari Allyn-Feuer, do not apparently have PhD’s.

https://en.wikipedia.org/wiki/Bioinformatics

228 posted on 02/01/2020 4:56:08 PM PST by MD Expat in PA (No. I am not a doctor nor have I ever played one on TV. The MD in my screen name stands for Maryland)
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To: Swordmaker

OK, you 2% of reported cases, me 4% of reported cases. Anything lower that 3% I donate $10 on your behalf, above 3% you do the same on my behalf. 3% exactly $5 from both of us.

Decision point is when the epidemic is declared over. (By WHO?)

I sure hope you win, even though I am currently on a fixed zero income!


229 posted on 02/01/2020 5:06:27 PM PST by null and void (The government wants to disarm us after 243 yrs 'cuz they plan to do things we would shoot them for!)
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To: Spktyr

Thanks !


230 posted on 02/01/2020 5:23:55 PM PST by HollyB
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To: MD Expat in PA
Yes. But the latter ones I recall were in “soft sciences” - sociology journals and were purposely bogus to make a point.

I always want to be skeptical of any published research in the squishy "sciences". . . too easy to squish and squeeze the dust, the language, and hence the conclusions, especially lately.

Now, it’s spilled over into harder sciences. Alas and alack. Woe to all of us as "scientists" fudge or even create data out of nothing to create what they need to push an agenda. I see it in everything from archaeology to astronomy to medicine to nuclear physics to climate "science." (I put that last on in quotation marks because it has become more of a cult-like religion than anything resembling science.) we will all be worse for the destruction of the scientific method.

231 posted on 02/01/2020 5:36:02 PM PST by Swordmaker (My pistol self-identifies as an iPad, so you must accept it in gun-free zones, you hoplophobe bigot!)
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To: null and void
OK, you 2% of reported cases, me 4% of reported cases. Anything lower that 3% I donate $10 on your behalf, above 3% you do the same on my behalf. 3% exactly $5 from both of us.

Decision point is when the epidemic is declared over. (By WHO?)

I sure hope you win, even though I am currently on a fixed zero income!

Done.

232 posted on 02/01/2020 5:40:43 PM PST by Swordmaker (My pistol self-identifies as an iPad, so you must accept it in gun-free zones, you hoplophobe bigot!)
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To: PIF

“Sword, there are rumors that the Chinese are doing what they did in ‘89 by cremating the bodies and, presumably, flushing the ashes down the sewers to hide the true numbers from their public for obvious reasons.”

now we’re speculating about things based on rumors ... btw,what are they telling the families and relatives of those who they cremated and flushed?


233 posted on 02/01/2020 7:20:37 PM PST by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: catnipman

tw,what are they telling the families and relatives of those who they cremated and flushed?


Same as in 89. Nothing. U imagine that the CCP is sort of like a US political party?


234 posted on 02/02/2020 2:20:56 AM PST by PIF (They came for me and mine ... now its your turn)
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To: UCANSEE2

I’m not technically qualified to answer that question - are you?
Seems like some folks with the qualifications are leaning to not engineered and the one crew who said it was is being called wrong...time will tell.


235 posted on 02/02/2020 3:30:40 AM PST by trebb (Don't howl about illegal leeches, or Trump in general, while not donating to FR - it's hypocritical.)
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To: trebb
Thank you for the response.

I’m not technically qualified to answer that question - are you?

No.

Seems like some folks with the qualifications are leaning to not engineered and the one crew who said it was is being called wrong...time will tell.True. Allow me to lay out some possibilities.

A new virus can occur from natural mutation.

A new virus can occur from manipulated mutation (the old method).

A new virus can occur from engineering (gene editing).

A new virus can occur from engineering and can then undergo manipulated mutation.

A new virus can occur from engineering and can then undergo natural mutation.

So, only the first one is totally a 'no human intervention involved'. Just because 'they' state that the virus does show that the latest mutation was 'engineered' doesn't mean it wasn't originally produced in a lab and then mutated to it's current form. Maybe they didn't plan on it mutating to it's current form. Maybe it's like the glue on POSTIT notes. It's not what the engineers at 3M were TRYING to manufacture.

BOTTOM LINE: Saying it wasn't engineered to be a bio-weapon with the current characteristics doesn't mean it wasn't produced through human experimentation.

236 posted on 02/02/2020 6:47:46 AM PST by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: UCANSEE2

I agree - the trouble is asserting what we cannot know...I wouldn’t be surprised to find out the Chicoms were “playing” with nature and screwed up...if that is the case, i hope we find out for sure and President Trump uses the leverage to twist their nipples until the scream in agony.


237 posted on 02/02/2020 7:40:44 AM PST by trebb (Don't howl about illegal leeches, or Trump in general, while not donating to FR - it's hypocritical.)
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To: Swordmaker; proust

I got a data set and have been running numbers, if I take today’s confirmed cases and today’s deaths it looks like after the 6th day the percentages stabilize near 2.15%

I expected a lag in the deaths vs confirmed cases, it might still be there, but the calculations don’t show it stabilizing very well yet.

Will work on the recovered numbers next. That looks pretty grim, almost 17,000 confirmed cased and only 525 recovered.

Hopefully either the Thai or the Indian treatment protocols will start boosting those numbers.

Still hoping you win...


238 posted on 02/02/2020 5:28:26 PM PST by null and void (The democrats just can't get over the fact that they lost an election they themselves rigged!)
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To: trebb

I think this is twisting the chicoms nipples. trump just needs to watch.


239 posted on 02/02/2020 5:45:07 PM PST by Black Agnes
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To: null and void
Will work on the recovered numbers next. That looks pretty grim, almost 17,000 confirmed cased and only 525 recovered.

Still no data on what they are defining as "recovered."

240 posted on 02/02/2020 6:17:46 PM PST by Swordmaker (My pistol self-identifies as an iPad, so you must accept it in gun-free zones, you hoplophobe bigot!)
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