There’s the filibuster threat. Don’t know if that can be done away with prior to a USSC nomination.
There’s the Reid Nuclear Rule, too. Plus a Mike Pence as President of the Senate.
Of course it can be done, but likely McConnell won't. The Senate can do so with a 51 vote majority (or likely 50 + Pence). But it is a political matter, not a legal one. The GOP does not want a justice tainted by the perception they were shoved through without "proper deliberation."