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Ebola patient receives experimental treatment in Dallas hospital
Dallas Morning News ^ | 12:47 pm on October 6, 2014 | Sherry Jacobson

Posted on 10/06/2014 11:08:08 AM PDT by palmer

Thomas Eric Duncan, the Liberian national who is fighting a severe Ebola infection in Dallas, is getting an experimental treatment, the hospital announced Monday.

The drug is an investigational medication, brincidofovir, for Ebola Virus Disease.

Chimerix, Inc., a biopharmaceutical company today announced that brincidofovir has been provided for potential use in patients with Ebola Virus Disease. ...

(Excerpt) Read more at thescoopblog.dallasnews.com ...


TOPICS: Business/Economy; Government; US: Texas
KEYWORDS: brincidofovir; chimerix; ebola; ebolatreatment; thomasduncan; uspatientzero
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To: Black Agnes

I wonder if this is going to be a $100 drug like lamivudine or a $100,000 drug like some other specialized antivirals.


21 posted on 10/06/2014 11:26:35 AM PDT by steve86 (Prophecies of Maelmhaedhoc OÂ’Morgair (Latin form: Malachy))
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To: steve86

It’s a ‘new’ drug and probably still has 7 years left on patent.

So I’ll go with $100,000 per dose Alex.

Meanwhile, the Africans will just use lamivudine. Till WHO finds a way to shut down their shipments.


22 posted on 10/06/2014 11:27:41 AM PDT by Black Agnes
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To: steve86

I guess if it was being developed to treat adenovirus infections it must be projected to be quite inexpensive.


23 posted on 10/06/2014 11:29:04 AM PDT by steve86 (Prophecies of Maelmhaedhoc OÂ’Morgair (Latin form: Malachy))
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...
Ping…

A link to this thread has been posted on the Ebola Surveillance Thread

24 posted on 10/06/2014 11:31:04 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: dan on the right

I stand corrected. Did more research. CDC is out of ZMapp. The manufacturer is trying to make more asap; but none available now. Unclear when. Only had a couple of doses. Not proven; but did seem to work with two early cases.


25 posted on 10/06/2014 11:31:11 AM PDT by dan on the right
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To: palmer

I thought this yard bird was dead. Treatments must really work well.


26 posted on 10/06/2014 11:31:42 AM PDT by Lion Den Dan
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To: Black Agnes

Thanks for the info. I didn’t read the article either, I only posted it.


27 posted on 10/06/2014 11:33:00 AM PDT by palmer (This comment is not approved or cleared by FDA)
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To: GrandJediMasterYoda
How about we try the “experimental treatment” of impeaching Obama, enforcing border LAWS, and banning all flights from West Africa?

With you 100%.

28 posted on 10/06/2014 11:33:03 AM PDT by Logical me
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To: Lion Den Dan

I thought he dead too. If this works, I will be amazed.


29 posted on 10/06/2014 11:34:06 AM PDT by palmer (This comment is not approved or cleared by FDA)
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To: Vinnie

I would triple that number. A one-night stay is pretty darned expensive, not to mention the care this guy’s apparently getting. I thought he was dead.


30 posted on 10/06/2014 11:34:36 AM PDT by combat_boots (The Lion of Judah cometh. Hallelujah. Gloria Patri, Filio et Spiritui Sancto!)
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To: palmer
Wow. It appears this guy was right and his gamble to get to an American hospital and world class treatment worked!

With open borders and no restrictions on travel from these Ebola countries, expects thousands more of these cases...

31 posted on 10/06/2014 11:34:42 AM PDT by Gritty (Obama wants to wage war by measuring it out in teaspoons - Ralph Peters)
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To: palmer
I have no idea how people manage to fight it off.

Only a guess, but they may have been exposed to degraded fomites in the wild at some point and built some sort of resistance--if that would work.

32 posted on 10/06/2014 11:36:30 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: Gritty

There were dozens of Liberians on just one flight from Brussels to Newark (the puking guy flight). There are “dozens” who have failed the medical check in Monrovia. We are screwed. Personally I don’t feel like there is a big threat of breakout, but innocents will die and we will spend billions.


33 posted on 10/06/2014 11:37:36 AM PDT by palmer (This comment is not approved or cleared by FDA)
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To: Black Agnes

34 posted on 10/06/2014 11:37:49 AM PDT by 11th_VA
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To: 11th_VA

LOL.


35 posted on 10/06/2014 11:38:39 AM PDT by Black Agnes
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To: Smokin' Joe

Seems like a good theory to me. The science text say you either get rapidly worse (after onset of major symptoms) or rapidly recover. That’s why I believe Duncan is not going to make it even with this treatment.


36 posted on 10/06/2014 11:39:20 AM PDT by palmer (This comment is not approved or cleared by FDA)
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To: Vinnie

What do you think the dollar amount is for his treatment so far?
$150,000 ? bet that’s not far off.”

I would expect that it is way, way, way more than that. You have to know that they are throwing the kitchen sink at him to keep him alive and stop the deterioration of his internal organs. Of course, like all other information coming out about this crisis, we will never truly know the truth.


37 posted on 10/06/2014 11:42:02 AM PDT by Grams A (The Sun will rise in the East in the morning and God is still on his throne.)
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To: palmer

We’ll see. This seems to be a hail mary since he was reportedly already on the ventilator.

The drugs seem to work best when given between days 1 and X of symptoms but after day X don’t make any difference.

I wonder if this hail mary is to try to stave off the inevitable misdiagnosis lawsuit from the family that we all know is coming.


38 posted on 10/06/2014 11:42:17 AM PDT by Black Agnes
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To: Black Agnes
That’s structurally related to the one being used by this Liberian doctor with amazing recovery rates:

Seems like it's about time to hear from the Liberian doctor again. Has he treated another set of 15 patients with lamivudine? What is the updated success rate? Are any of his associates experimenting with it as well?

39 posted on 10/06/2014 11:44:20 AM PDT by steve86 (Prophecies of Maelmhaedhoc OÂ’Morgair (Latin form: Malachy))
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To: palmer
One of the doctors in Africa had said "If they bleed, they die."

I'm not sure whether Duncan was bleeding internally or not.

I reckon we'll find out...

40 posted on 10/06/2014 11:44:53 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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