Posted on 04/01/2013 12:23:05 PM PDT by abigailsmybaby
ABSTRACT Male and female homosexuality have substantial prevalence in humans. Pedigree and twin studies indicate that homosexuality has substantial heritability in both sexes, yet concordance between identical twins is low and molecular studies have failed to find associated DNA markers. This paradoxical pattern calls for an explanation. We use published data on fetal androgen signaling and gene regulation via nongenetic changes in DNA packaging (epigenetics) to develop a new model for homosexuality. reduced androgen sensitivity in XX fetuses and enhanced sensitivity in XY fetuses, and that this difference is most feasibly caused by numerous sex-specific epigenetic modifications (epi-marks) originating in embryonic stem cells. These epi-marks buffer XX fetuses from masculinization due to excess fetal androgen exposure and similarly buffer XY fetuses from androgen underexposure. Extant data indicates that individual epi-marks influence some but not other sexually dimorphic traits, vary in strength across individuals, and are produced during ontogeny and erased between generations. Those that escape erasure will steer development of the sexual phenotypes they influence in a gonad-discordant direction in opposite sex offspring, mosaically feminizing XY offspring and masculinizing XX offspring. Such sex-specific epi-marks are sexually antagonistic (SA-epi-marks) because they canalize sexual development in the parent that produced them, but contribute to gonad-trait discordances in opposite-sex offspring when unerased. In this model, homosexuality occurs when stronger-than-average SA-epi-marks (influencing sexual preference) from an opposite-sex parent escape erasure and are then paired with a weaker-than-average de novo sex-specific epi-marks produced in opposite-sex offspring. Our model predicts that homosexuality is part of a wider phenomenon in which recently evolved androgen-influenced traits commonly display gonad-trait discordances at substantial frequency, and that the molecular feature underlying most homosexuality is not DNA polymorphism(s), but epi-marks that evolved to canalize sexual dimorphic development that sometimes carryover across generations and contribute to gonad-trait discordances in opposite-sex descendants.
(Excerpt) Read more at jstor.org ...
Thank you! That’s what I thought they were saying. Just needed a little confirmation. I really do appreciate you responding.
Yes, experience has a huge impact on sexuality, which you don’t have to be a wacky Freudian to see. Genes are easier to study, in a controlled manner, anyway. So scientist will continue to think all or most of the answer is in biology rather than psychology/sociology, not to mention fields with no pretence of being scientific.
Visit a prison or unisex boarding school if you don’t believe me.
See post #17. Puts it in a very small nutshell.
Basically they are saying that a man's sexual attraction to women causes epigenetic markers that can pass on to their daughter if it is not properly erased and if it is combined with weak epigenetic markers from the mother telling the daughter to be sexually attracted to men.
Conversly a woman's sexual attraction to men causes epigenetic markers that can pass on to their son if it is not properly erased and if it is combined with weak epigenetic markers from the father telling the son to be sexually attracted to women.
So apparently they are back to male homosexuality being caused by strong mothers and indifferent fathers! /s
Homersexality is a behavior. It is not a race.
Behaviors are complex because God created us complex. There is no one cause.
one of the causes is imprinting:
http://en.wikipedia.org/wiki/Imprinting_(psychology)
After reading it (and I’m no geneticist), it seems as if the conclusion is that homosexuality is not due to a gene, but due to something else carried over from the parent of the same gender with messes up the fetus. Does this mean a future cure would not require advanced gene therapy, and might even be medicinal?
It’s nonsense.
People change all the time - decide they’re “gay”, and those who leave the sodomy life. Some even were normal, then become “gay” and then become normal again.
I’m with you there.
More likely the rise is explicable by the rise in acceptance of gayness in the culture. The more okay we think it is to be gay, the more gays there are. I can’t think that’s a coincidence.
There’s the possibility that removing the stigma merely prompted closet cases to come forward, rather than more people becoming gay because it’s easier to be gay. But then I’d have to think of all these men who lived their entire lives only or mostly having sex with women as *really* gay, and lying to others and themselves the whole time. Which I find hard to swallow.
Not that there are no such things as closet cases. But to me gay is as gay does for the majority of us. Heterosexual copulation is abstracted enough from basic biological mandates as it is, married sex moreso. Heck, people hump holes in trees for satisfaction, for as much as the sexual object means to their satisfaction. It is habit that determines orientation.
That’s a good question. I believe they stated that at some point it could be possible to protect the baby during gestation from androgen signaling misfires. Of course I’m paraphrasing but that’s the way I understood it.
We recently had an article where a mouse gene that controls hair thickness, number of sweat glands, breast size and shape of teeth was replaced with a human gene that does the same thing.
Turns out that mouse gene is virtually identical to the human gene so such things are possible.
Actually, I had no idea we were that advanced already, but there you have it.
Future technology will probably give you something like a glucophage pill that reprograms your DNA everyday ~ so you can metabolize insulin and grow new nerve tissue. Later on they'll get around to a process that makes the fixes more permanent.
The day when gays can blame it on genes is fast coming to an end, yet, if they want to tell us it's all about epigenetics that opens the door to imposing a FIX on them whether they want it or not.
A brighter spot in this means that Cystic Fibrosis and a host of other 'diseases' can be repaired.
DO YOU HAVE A COPY OF THIS IN ENGLISH?.........
It always puzzles me how those who think of people as “born that way” explain suddenly homosexuality upon entering prison. It’s not as if people spontaneously change their race, unless they’re Eddie Murphy with a Hollywood budget. The explanation is, well, that’s different, because there isn’t any alternative. There are alternatives, obviously. But supposey straight men turn gay, anyway. Because apparently the act means more to them than how the sexual object is shaped.
Well, Japanese have been eating soy everything a lot longer than we have........
AT the level of the egg and sperm ~
That is, it's not part of your genes ~ rather it's just part of an epigenetic signal.
That would seem to provide some support for the "born this way" crowd. Not genetically born that way, but due to the effect of epigenetic signals on the developing fetus. So that raises a lot of questions such as: what caused the epigenetic signal in the first place; how many generations does it go back; can there be screening for the signal the way there is screening for genetic markers.
There might also be the question of whether the epigenetic signals are caused by environmental toxins, or maybe even behaviorally induced by the ancestor.
Interesting study. I certainly don't have the expertise to understand it, but it is certainly worth examining.
garbage.
there is no genetic component.
this is just propaganda doublespeak. It is based on disproven and outdated science. Fundamentally dependent on studies already exposed for deception and fraud.
This is just to justify the USSC buying the MYTH OF IMUTABILITY.
Thanks for your service! It’s not you, so rest easy.
Here’s the first line of this abstracts modern English/jargon:
“Male and female homosexuality have substantial prevalence in humans.”
I tried to read the article, but it’s so heavily larded that it is nearly incomprehensible, keeping in mind that it is technical, or as the Duck Dynasty guys say, “This is si-intistic stuff!”
So here’s an excerpt from Orwell’s “Politics and the English Language”:
“Now that I have made this catalogue of swindles and perversions, let me give another example of the kind of writing that they lead to. This time it must of its nature be an imaginary one. I am going to translate a passage of good English into modern English of the worst sort. Here is a well-known verse from Ecclesiastes:
I returned and saw under the sun, that the race is not to the swift, nor the battle to the strong, neither yet bread to the wise, nor yet riches to men of understanding, nor yet favour to men of skill; but time and chance happeneth to them all.
Here it is in modern English:
Objective considerations of contemporary phenomena compel the conclusion that success or failure in competitive activities exhibits no tendency to be commensurate with innate capacity, but that a considerable element of the unpredictable must invariably be taken into account.”
A translation of Rice’s brave first sentence of jargon into good English?
“We’re all gay. More or less.”
Yeah, right.
“Molestation drives most homosexuality.”
Any kind of abuse and trauma can cause it if the events are sexualized.
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