I felt the same way when we took our vacation out West. While I loved the West, the wide open space gave me the willies. I also live back in the hills although I’m not as remote as you are. I still have to live fairly close to work but the day I retire I plan to sell this old farm and head to the mountains where there are no people, if there is still a place.
I’m close to the Great Smokey Mountains and told my husband that I’d like to sell the farm and move back to the mountains. He wants to move to Wyoming. That would drive me nuts unless it was in the mountains. I’m descended from a long line of Appalachian hill folk.
The last great “nobody” place is in the deep hills of WV, just south of the western end of MD.
It is SO beautiful there it will break your heart.
Then, come back. It's awful cold in Wyoming.