Posted on 12/19/2004 2:33:30 PM PST by beavus
Researchers at Rockefeller University in the US have made the first tentative steps towards creating a form of artificial life.
Their creations, small synthetic vesicles that can process (express) genes, resemble a crude kind of biological cell.
The parts for their "vesicle bioreactors", as they call them, all come from diverse realms of life.
The soft cell walls are made of fat molecules taken from egg white. The cell contents are an extract of the common gut bug E. coli, stripped of all its genetic material.
This essence of life contains ready-made much of the biological machinery needed to make proteins; the researchers also added an enzyme from a virus to allow the vesicle to translate DNA code.
When they added genes, the cell fluid started to make proteins, just like a normal cell would.
Jelly fish
A gene for green fluorescent protein taken from a species of jellyfish was the first they tried. The glow from the protein showed that the genes were being transcribed.
With a second gene, from the bacterium Staphylococcus aureus, the researchers got their cells to make small pores in their walls.
M. genitalium bacteria Some bacteria can survive with just a few hundred genes These let nutrients in from the surrounding "soup", so that the cells could function, in some instances, for several days.
Albert Libchaber, who heads the project, stresses that these bioreactors are not alive - they're performing simple chemical reactions that can also happen in cell-free biological fluids.
But the research is one strand in a new field called synthetic biology, where the aim is to re-design entire organisms, or recreate them from scratch.
The bio-entrepreneur Craig Venter, who headed the commercial venture to decode the human genome, is currently trying to strip a bacterium down to the minimum set of genes needed for survival.
Synthetic virus
Two years ago, another team showed that polio viruses could assemble themselves from off-the-shelf chemical components mixed in a test-tube.
And several chemists are exploring the kinds of chemical reactions that may have preceded life.
Albert Libchaber's hope is to build up towards a minimal synthetic organism, with a designed cell wall, and a mixture of gene circuits that would let it maintain itself like a living cell.
As these constructs become more lifelike, the rest of us will have to start rethinking the nature of life.
"This is rather philosophical," says Dr Libchaber.
"For me, life is just like a machine - a machine with a computer program. There's no more to it than that. But not everyone shares this point of view," he told the BBC.
He also stresses that there is no danger in the experiments. Not only are his cells artificial, they can function only in the nutrient medium he supplies them.
He said: "If you take our system out of its environment, it just doesn't function."
Details of Libchaber's work with Vincent Noireaux have been published by the journal Proceedings of the National Academy of Sciences.
...Speaking of synthetic, how about those Democrats pretending to be pro-life to help them next election!
Seriously this could be future good news, far better this than embryonic stem cells!
And (from the title)I thought this was about a recount in Ohio...
Looking for trouble today, bud? (grin)
I'm reminded of a story:
A group of scientists were discussing which one of them was going to tell God they didn’t need him anymore. Finally, one volunteered and went to speak to God.
The scientist said to God, ‘Some of us have been thinking and have come to tell you that we really don’t need you anymore. You see, we’ve been coming up with great theories and ideas, we’ve cloned sheep, and we're on the verge of cloning humans. So as you can see, we really don’t need you.’
God nods understandingly and says. ‘I see. Well, no hard feelings. But before you go let's have a contest. What do you think?’
The scientist says, ‘Certainly . . . what kind of contest?’
God said, ‘A man-making contest.’
The scientist said, ‘Sure! No problem.’
The scientist bent down, picked up some dust and said, ‘OK, I’m ready!’
But God replied, ‘No, no, no . . . You make your own dust.’
ping
As the depressed Syrian tow-truck driver would say, "Always."
"For me, life is just like a machine - a machine with a computer program. There's no more to it than that. But not everyone shares this point of view,"
I have no problem with his definition of life. However, I wished he would realize to have computer program requires a "programmer" not just "chance."
What makes you think he doesn't think so?
yep, there's butthead!!
Truer words were never spoken. Now who do you suppose designed the environment?
Yeah. Heh-heh heh heh-heh heh heh. Butthead sucks. Heh heh heh-heh heh.
Who?
An easy game to play but it bores the hell out of my 5 year old granddaughter.
"Ha-la-ha-la-ha-la-ha-la-la".
"who do you suppose designed the environment?"
An easy game to play but it bores the hell out of my 5 year old granddaughter.
Then maybe you should start posting instead of her.
Why's that, she's kicking your ass all by her 5 year old self.
This is the clincher that will always bite them. They won't be able to create life from dead things, as they claim nature did.
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