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Anthrax Sent Through Mail Gained Potency by the Letter
New York Times ^ | Tuesday, May 7, 2002 | By WILLIAM J. BROAD and DAVID JOHNSTON

Posted on 05/06/2002 11:22:38 PM PDT by JohnHuang2

May 7, 2002

Anthrax Sent Through Mail Gained Potency by the Letter

By WILLIAM J. BROAD and DAVID JOHNSTON

Deepening the mystery of the biological attacks that terrified the nation last fall, federal investigators have discovered that the anthrax sent through the mail, in general, grew more potent from one letter to the next, with the spores in the final letter to be opened — the one sent to Senator Patrick J. Leahy of Vermont — the deadliest of all.

The finding has surprised and worried investigators, who say it poses a new riddle: was the culprit an amateur making gradual improvements through experimentation, a malevolent professional intentionally ratcheting up the potency of the germ powder, or someone else entirely?

It also suggests that after more than six months of painstaking effort, government experts investigating the anthrax strikes are still at sea. Part of the problem, they admit, is a lack of advisers skilled in the subtleties of germ weapons.

The discovery of the progressive potential deadliness of the anthrax is the latest conclusion of scientific testing that investigators are hoping will help crack a case that has baffled the F.B.I. since the first anthrax fatality: that of Robert Stevens, a photo editor at a Florida supermarket tabloid, who died on Oct. 5.

With five anthrax deaths linked to the contaminated mailings, the F.B.I. inquiry has consumed millions of hours of interviews, neighborhood sweeps and other detective work. For example, F.B.I. laboratory analysts matched the serrated ends of the strips of cellophane tape used to seal the anthrax letters. That meant that whoever sealed the letters, without leaving any fingerprints, tore off successive strips of tape from the same roll, officials said.

But investigators acknowledge that they still have no idea who is behind the tainted letters. So they are increasingly turning to science to unravel the mystery. Tests being conducted at several private laboratories may reveal the precise biological signature of the anthrax used in the mailings, helping to narrow the search for the laboratory from which it came.

Analyses of the anthrax sample and the chemicals used to coat it could leave telltale clues to the techniques and equipment used to manufacture the germ material.

Investigators previously believed that the anthrax sent to Mr. Leahy, the Democrat who is chairman of the Senate Judiciary Committee, and Tom Daschle, the Senate majority leader, were identical in strength. Each letter was mailed from Trenton on Oct. 9, 2001. Each had the same photocopied message inside.

But it turns out that the Leahy anthrax is finer, its spores having a smaller range of particle sizes, officials familiar with the federal investigation said.

"It could be that the final steps of the processing were done in steps," a senior government official said. "You take it so far, and take off a bunch. You go further, and take off another bunch."

Despite the increasing sophistication of the anthrax, investigators say they still judge that the deadly powder could have been made in any of thousands of biological laboratories, though getting the right starter germs would have been difficult.

An aide to Senator Daschle opened the letter on Oct. 15, and officials quickly warned that its anthrax was of high quality compared with earlier mailings, to news media offices in New York. The Leahy letter was impounded, along with all other Congressional mail, and was not discovered until Nov. 16. Investigators made painstaking safety and forensic preparations before opening it in early December.

The analysis of the contents of the Leahy letter is proceeding slowly, the investigators say, because they are learning the science as they go along and want to make sure that none of the scarce, lightweight but extremely valuable evidence is lost, corrupted or misinterpreted. They are getting help, they say, from scores of scientists across the nation.

"We'll have to take this into court," the law enforcement official said of the evidence. "We had to assure ourselves that we had a quality program."

A senior Bush administration official expressed sympathy for the F.B.I. because the inquiry had grown so scientifically complex and knowledgeable advisers are so few.

"They're having to review a lot of the initial takes on things," the official said. "There's an evolving picture. The bureau has gone back to scratch to invent the science."

It is sometimes hard even to do reappraisals. In the Florida case, no letter or residual powder was ever recovered, leaving many questions about the anthrax there.

Federal officials said the first wave of well-documented attacks with mailed anthrax — in letters from Trenton postmarked Sept. 18 to NBC News and The New York Post — was relatively crude. The powder was heavily contaminated, they said, with what biologists call vegetative cells — anthrax bacteria before processing in the laboratory turns them into hardened spores. Vegetative cells in dry anthrax powder are generally dead and therefore harmless, experts said.

By contrast, the tiny spores live in a dormant state. Individual ones are light enough to float easily in the air and, if inhaled, small enough to reach deep into human lungs, eventually germinating into bacteria and causing the respiratory form of the disease, which can be fatal. They can also cause the less dangerous cutaneous form if rubbed into the skin.

Last October, alarm bells rang when the Daschle powder was found to be nearly pure spores. The danger was driven home when nasal swabs came back positive for 28 people in the Senate Hart building, where the letter was opened.

The F.B.I. in early November characterized the Daschle powder as "much more refined, more potent, and more easily dispersed" than the New York media anthrax. The mailer's letters hinted at the danger. The media ones warned the openers to take penicillin. But the Daschle letter said flatly, "You Die Now."

As federal experts investigated the residual Daschle sample, they found the picture becoming fuzzier. On one hand, the concentration of the anthrax was extraordinarily high — roughly equal to that made in the abandoned American germ weapons program, a trillion spores per gram.

But federal experts now say the particles turned out to have a large size range. While single spores predominated, the experts said, some Daschle clusters ranged up to 40 microns wide — far too big to penetrate human lungs. A micron is one-millionth of a meter, and a human hair is 75 to 100 microns wide. The big clusters suggested the powder was far less than weapons grade.

Private experts disagree on just how much less. Ken Alibek, a former Soviet germ official who is now president of Advanced Biosystems, a consulting company in Manassas, Va., called the Daschle anthrax mediocre.

"It was not done with a regular industrial process," Dr. Alibek said in an interview. "Maybe it's homemade."

Recipes that antigovernment militia groups circulate at gun shows might suffice to make the deadly powder, he said.

But William C. Patrick III, a scientist who made germ weapons for the American military and is now a private consultant on biological defense, rated the Daschle anthrax as 7 on a scale of 10.

"It's relatively high grade," Mr. Patrick said, "but not weapons grade."

In addition to particle size, federal experts are investigating whether the anthrax powders have electrostatic charges that affect dispersal and chemical coatings meant to increase potency and shelf life.

Federal investigators saw the Leahy anthrax as an opportunity to clear up ambiguities and deepen the analysis. Since no powder had been lost in the letter's opening, they had more to work with. Still, the amount, typical of the tainted letters, was remarkably small — just 0.871 grams. A pat of butter weighs 10 grams.

Last week, government officials said the most recent analyses showed that the Daschle and Leahy powders were quite different, the latter finer and more uniform.

"You can characterize the Leahy as having a smaller particle range," one official said.

In general, he added, the ability of federal investigators to do deeper analyses because of the relatively large amounts of powder in the Leahy letter is producing "real interesting results."

A biologist aiding in the investigation said the increasing potency of anthrax in the letters might suggest that the attacker was a thief who stole several samples.

"Maybe he didn't pocket one vial but two or three, if we're assuming this was an opportunist," this scientist said.

Dr. Alibek raised another possible factor. The F.B.I., he said, needed to weigh the possibility that post office sorting machinery might have had an effect. "It could be an additional process of milling," he said, "like a mortar and pestle."

Experts said the Daschle and Leahy letters, starting at the same place in New Jersey on the same date and ending up at the same destination in Washington, appear to have taken similar if not identical postal routes. Dr. Alibek agreed but said the same sorter could apply more pressure to one letter than another. He added that the overall grade contrasts were probably caused by "different batches of the product, one more sophisticated than the other."

Investigators have also been studying the envelopes, officials say, and have found that the paper had very large pores — up to 50 microns wide. That is bigger than the largest Daschle anthrax clusters and suggests how the powder could easily escape individual letters to contaminate the general mails.

"It had to be one of the most porous materials," an official said of the attack envelopes compared with standard ones. "Whether that was by chance or design, I have no idea."


TOPICS: Anthrax Scare; Front Page News; News/Current Events
KEYWORDS: anthrax; anthraxscarelist; antraz; injury; letters
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To: Mitchell
Got the impression he was a mentally imbalanced person with access to a top secret biological program. Those guys go through a backgound check so he must have been a U.S. citizen. No details .... sorry.

The source was very high up in law enforcement in NY and left the state right after 911. If had I lived in NYC I would be gone as well.

21 posted on 05/07/2002 7:53:03 AM PDT by ex-Texan
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To: browardchad
The more the envelopes are handled in highspeed automation equipment, the more likely the existing pores will be expanded - you handle a piece of mail enough times and the fibers in the envelope or other cover will start to break down. The misrouted pieces had the most finely ground anthrax and the biggest pores. These envelopes started out "standard" for "postage affixed" envelopes which are purchased at the post office. You may buy them one at a time unless you buy them from a machine where they come in packs of 5 or 10 (I believe that's 5 or 10, but they have been sold in other units to minimize change requirements on the vending machine).
22 posted on 05/07/2002 8:24:08 AM PDT by muawiyah
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To: Mitchell; Alamo-Girl
Your# 20)
Did the story include the nationality of the person? Or anything else that would shed some light on this?

Right!...........and exactly WHAT COUNTRY/NATION is he/she/it being 'held' in?

23 posted on 05/07/2002 8:24:32 AM PDT by maestro
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To: JohnHuang2; EternalHope; expatriot; Mitchell
Wouldn't progressively smaller particle sizes be consistent with pouring a sample from a container that had been in shipment. For example a sealed film container could easily slip through customs. In shipment the powder should settle with more densely packed particles (smaller?) on the bottom. If the particle size is progressively smaller as the anthrax contents are poured from a container and that progression matches the progression from the tape dispenser used to seal the envelopes then one could assume a common container whose contents had settled would be evident.?
24 posted on 05/07/2002 8:35:03 AM PDT by Ranger
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To: ex-Texan
The source was very high up in law enforcement in NY and left the state right after 911.

That negates your source right there -- New Yorkers in law enforcement, and particularly those in NYC, have not left the state; they're mad as hell, and have been working their butts off since 9/11. Sounds like your source is a bureaucrat, who typically knows nothing, but likes to pretend they do.

25 posted on 05/07/2002 9:14:37 AM PDT by browardchad
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To: Mitchell; Nogbad; expatriot
The tape analysis indicates the same roll of tape was used to seal the envelopes.

While interesting, the tape analysis doesn't in any way constrain the timeline for filling the envelopes. It just means the tape wasn't used for anything else.

26 posted on 05/07/2002 9:36:43 AM PDT by keri
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To: expatriot
The tape analysis however indicates that the packaging was done at the same time and does not coincide with a timeline of the production if it was indeed staggered.

Yes! The above is entirely consistent with someone:
- acquiring samples from different sources
- testing the samples for effectiveness
- developing a unified attack plan
- preparing the letter "bombs" at one time
- then traveling to various locales to mail the letters

It seems quite preposterous to assume a single individual
figured out how to weaponize anthrax in a few days between
the first mailing and the last.
27 posted on 05/07/2002 9:53:13 AM PDT by My Identity
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To: EternalHope; expatriot; keri; Nogbad; Mitchell
the anthrax in each letter was sorted into progressively smaller and more consistent spore sizes. Why they did this is a mystery, but it certainly ought to give us some clues into the manufacturing process they used

I don't think they "did this". See my post 4 above.

OBL had no team of brilliant biochemists.
OBL had no leading-edge biochem lab facilities.
OBL had no manufacturing process.

What OBL had was money and time. They successfully acquired (probably bought, possibly stole) a half-dozen different samples from a half-dozen different sources. They test them on animals in their Afghan camps. They package it up as best they can (envelopes and tape). They send the weak stuff to the media. They send the strong stuff to the pols. End of story.

More interesting is the "why" behind the attacks.
28 posted on 05/07/2002 10:12:15 AM PDT by My Identity
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To: Ranger
Wouldn't progressively smaller particle sizes be consistent with pouring a sample from a container that had been in shipment.

Interesting thought.

The anthrax used would have been in a sealed "glove box" with all the components already in the box (tape, envelopes w/letters already written, anthrax container, etc.). The anthrax would probably have been scooped out of the container rather than poured. If the container had been jiggled for an extended period of time, then it might be possible that the heavier particles would have settled to the bottom.

29 posted on 05/07/2002 10:16:06 AM PDT by EternalHope
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To: expatriot
I disagree with the theory of refinement in the mail.

I agree with your disagreement. Leahy's sample was practically perfect. No detritus. Single spores. Free floating. Further, Leahy's letter was misrouted and sat in a pile of other letters for over a month, was it not? The fact that it came out so perfect suggests that Postal Service handling had no effect on the material.
30 posted on 05/07/2002 10:19:54 AM PDT by My Identity
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To: Ranger; Mitchell; Nogbad; Shermy; muawiyah
"Wouldn't progressively smaller particle sizes be consistent with pouring a sample from a container that had been in shipment?"

Excellent point. Larger, less dense, particles would "float" on the top. Smaller, more dense, particles would be found at the bottom of the container.

So, we have three competing theories which would tend to explain the quality differentials in the various mailings:

1. "Settling", as in all envelopes being filled in sequence from a single container.

2. "Samples", as if each envelope was filled with materials from separate manufacturing sources.

3. "Handling", as if the Daschle and Leahy envelopes were differentiated by the way the post office handled them.

In the latter case, I imagine it is more likely that such handling would degrade, rather than improve, the quality of the anthrax. Fully weaponized spores are de-ionized, while some processing/sorting equipment might tend to transfer an electrostatic charge -- which would cause the "clumping" described in the Daschle letter.

In any event, tracing all the tape to a single roll suggests that all the envelopes were probably filled in a single operation.

We know more today than we knew yesterday.

31 posted on 05/07/2002 10:43:58 AM PDT by okie01
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To: JohnHuang2
It also suggests that after more than six months of painstaking effort, government experts investigating the anthrax strikes are still at sea. Part of the problem, they admit, is a lack of advisers skilled in the subtleties of germ weapons.

Anyone who really believes that the FBI is in charge of the anthrax investigation needs his head examined. USAMRIID and Dugway have been set up to do that for ten years -- basically since it emerged that Saddam Hussein had abandoned his high-profile nuclear program and refocused his WMD effort on anthrax. The US government just contracted for 25 million doses of a new, experimental anthrax vaccine to treat the civilian population after a major release or multiple simultaneous releases in our cities. Yet we are supposed to believe that Bush has been content to let a bunch of stumblebums at the FBI fumble the ball for seven months. Truth is, there is nothing to figure out -- there hasn't been for months. The FBI's role is now strictly limited to beating off the press (in both senses of the term) while Bush figures out what to do about the situation.

32 posted on 05/07/2002 10:43:59 AM PDT by The Great Satan
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To: EternalHope; Ranger
Wouldn't progressively smaller particle sizes be consistent with pouring a sample

Nope. There are three data points:
1 - The NY Media samples:
    - pm 9-18-01
    - crude anthrax material, lots of detritus
    - warned to take penicillin
2 - Dashcle letter:
    - pure anthrax, but crudely processed (no detritus, but clusters from 1-40 microns)
    - known by mailer to be more deadly (You Die Now) suggesting it was pre-tested
3 - Leahy letter:
    - pure anthrax, but finely processed (no detritus, but clusters from 1-3 microns 1-2 spores)
    - known by mailer to be more deadly (You Die Now) suggesting it was pre-tested

Instead, consider individual sample bottles (from different sources) each poured individually into separate envelopes and sealed.
33 posted on 05/07/2002 10:52:19 AM PDT by My Identity
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To: okie01
three competing theories:

1. "Settling"
2. "Samples"
3. "Handling"


Nice overview okie!.

I think the "Settling" scenario is not viable for at least 2 reasons:
1 - The mailings were consistent: crude anthrax to media outlets. Weaponized anthrax to pols.
2 - There was no cross contamination between the 3 data points.
The NY media samples had lots of debris. "Settling" implies that there would have been at least a little debris in the two DC samples.

I think the "Handling" scenario is not viable for several reasons:
1 - as pointed out by others, handling would have a reverse effect, more clumping, not less.
2 - It is preposterous to think that sending a letter through the mail would randomly produce perfect, weaponized powder.
3 - The Leahy sample, even after extensive handling and sitting, came out perfect. This suggests that handling had little or no effect at all.

For this and other reasons, I am a "Samples" proponent.

In any event, tracing all the tape to a single roll suggests that all the envelopes were probably filled in a single operation.

Exactly! The mailings were not targets of opportunity, but part of a larger scheme.
34 posted on 05/07/2002 11:08:38 AM PDT by My Identity
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To: EternalHope; expatriot; keri; Nogbad; Mitchell; Ranger; My Identity; okie01; The Great Satan...
Successively smaller sample sizes
would conform to my previous hypothesis
that the mailings were
in part
an experiment.

The Donor wished to test the effectiveness
in a real-world situation
of various grades of anthrax.

35 posted on 05/07/2002 11:13:45 AM PDT by Nogbad
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To: Nogbad
The Donor wished to test the effectiveness
in a real-world situation
of various grades of anthrax.

Since the cover notes sent with the anthrax samples identified the sampels as anthrax -- negating any potential lethality -- your theory is complete bunk.

36 posted on 05/07/2002 11:16:53 AM PDT by The Great Satan
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To: The Great Satan
The US government just contracted for 25 million doses of a new, experimental anthrax vaccine to treat the civilian population after a major release or multiple simultaneous releases in our cities. Yet we are supposed to believe that Bush has been content to let a bunch of stumblebums at the FBI fumble the ball for seven months. Truth is, there is nothing to figure out -- there hasn't been for months. The FBI's role is now strictly limited to beating off the press...

Exactly! And the press, ever consistent, bought into the "Lone RW Nut" theory hook, line and sinker.

The Leahy anthrax is perfect. It has been described by weapons experts as the "Keys to the Kingdom." It is a very serious threat. However, based on available info, I don't believe OBL has any left (or very little).
37 posted on 05/07/2002 11:17:27 AM PDT by My Identity
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To: Nogbad
The Donor wished to test the effectiveness in a real-world situation of various grades of anthrax.

Nah! Why bother giving the feds more opportunity to catch you?
Why risk showing the Feds that you don't know what you are doing.
Why detract from the strategic impact of the attack?
38 posted on 05/07/2002 11:26:19 AM PDT by My Identity
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To: My Identity
However, based on available info, I don't believe OBL has any left (or very little).

Saddam would never have supplied al-Qaeda with anything more than small samples of anthrax; to do otherwise would be to risk an unauthorized mass dispersal, leading to massive nuclear retaliation against Iraq. That is not the plan. If he has pre-positioned stocks here for a large scale attack, my best guess would be a scheme were the supplies are in a left-luggage locker with a combination lock, or something equivalent. This would provide absolute security against uncontrolled release, while making it a straightforward matter to launch a retaliatory strike if the deterrent fails and we do attempt to kill Saddam or remove him from power.

39 posted on 05/07/2002 11:34:18 AM PDT by The Great Satan
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To: JohnHuang2; keri; The Great Satan; Mitchell; tymesup; Alamo-Girl; Shermy; aristeides; nimdoc...
OK. Here is the question.

Which is more likely?

1. The terrorists begged, bought,or stole
   a number of samples of anthrax
   then filled the letters.

2. The envelopes all were filled
   at the same time, at one location,
   i.e. the place where the anthrax was made,
   then passed back to the terrorists.

40 posted on 05/07/2002 11:45:38 AM PDT by Nogbad
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