It’s a denial of the Annunciation in a crass way. There’s no reading into it.
You read "denial of the annunciation" into it.
To my own eyes, the billboard is sacrilegious, quite crass at the least, but were they really trying to convey "denial of the annunciation"?
Why jump so hard at the WORST possible interpretation of what idea they were trying to convey? Ask yourself that.
Has there been any explanation from the creators of the offending work, just what they were trying to say? You're probably the wrong guy to ask that question of, for you seem to have your own mind completely made up.