I appreciate you posting the transcript - I would rather read than listen to a recording.
There is much in that message I agree with, primarily on what I see as the MAIN issue with regards to the RCC:
“And the question came up, is the Pope in heaven? And you hear all these people say, “Yes, yes, yes.” People have asked me, “Is the Pope in heaven?” And my answer is, “Is the Pope Catholic?” Isn’t that the answer? I think he is, I think the Pope is Catholic. Does he believe Catholic theology? Yes. He is the guardian of Catholic theology. Do you get to heaven by works, by Mary, by Penance, by Baptism, by confession, by Rosary? No. This is another gospel. This is not the true gospel.”
I do not agree with MacArthur (and others) who claim that anti-Christ is the same as “the man of sin” in 2 Thess 2:3. John’s description of anti-Christ is specific: “He is antichrist, that denieth the Father and the Son.” and “For many deceivers are entered into the world, who confess not that Jesus Christ is come in the flesh. This is a deceiver and an antichrist.”
Not every false teacher is anti-Christ, per the apostle John, who is the only NT writer to use this term.
A false church in league with a government - this looks more like “the beast” and has appeared in human history more than once.
“And the question came up, is the Pope in heaven? And you hear all these people say, “Yes, yes, yes.” People have asked me, “Is the Pope in heaven?” And my answer is, “Is the Pope Catholic?” Isn’t that the answer? I think he is, I think the Pope is Catholic. Does he believe Catholic theology? Yes. He is the guardian of Catholic theology. Do you get to heaven by works, by Mary, by Penance, by Baptism, by confession, by Rosary? No. This is another gospel. This is not the true gospel.”
Matt 22: 36 "Teacher, which is the great commandment in the law?" 37 Jesus said to him, "'You shall love the Lord your God with all your heart, with all your soul, and with all your mind.' 38 This is the first and great commandment. 39 And the second is like it: 'You shall love your neighbor as yourself.' 40 On these two commandments hang all the Law and the Prophets."
Entry into heaven is not based on what a person believes or how they think about God. It's how they live their life according to their religion.
Last time I checked, Catholics keep the two great commandments set forth by the Lord in the passage I quoted. To me, this trumps anything Paul wrote in Romans or anywhere else.
MacArthur has nothing I want. He is not a Christian in my estimation based on what his mind has twisted and his tongue spews as 'his truth';. If I believed in an anti-Christ, he would be my nominee. A false prophet at the very least.