No, but it does preclude your idea that Mary was sanctified at the Annunciation.
Nor does it imply that Mary was made perfect because of the grace of God bestowed on her.
If Mary was made perfect, there is no other way it could have happened but by the grace of God. Agree?
If the moon were made of green cheese, it would taste like gouda. Agreed?
Why do you wish me to hypothesize about something which cannot be?