NYPD detectives or Manhattan DA investigators cannot arrest Trump in Fl. He would need to be taken into custody by state or local LEOs and then an extradition hearing would be held in court. Trump would likely take it up the ladder to Fl SC. If they uphold extradition then DeSantis could deny it as he has that power. He loses either way. If he upholds exteadition no Trumper will ever vote for him. If he denies it he loses the GOPe, the Never Trumpers, and many independents.
The Governor has no discretion when presented with a facially correct request for extradition, and while the person sought may seek a writ of habeas corpus, the Florida Court may not interfere with the extradition, unless, while considering the writ (Florida Statutes, Title XLVII, CRIMINAL PROCEDURE AND CORRECTIONS, Sec.941.10 Rights of accused person; application for writ of habeas corpus ... )(2)... a court finds that the person in custody is not the same person named in the warrant, or that the person is not a fugitive from justice, or otherwise subject to extradition under s. 941.06, or that there is no criminal charge or criminal proceeding pending against the person in the demanding state, or that the documents are not on their face in order, the person named in the warrant shall be held in custody at all times and shall not be eligible for release on bail.
Given that Trump would not be eligible for bail, while litigating a writ of habeas corpus, I doubt he will take his case to the Florida Supreme Court.