Free Republic
Browse · Search
Topics · Post Article

Skip to comments.

Human Fat Cells Host CCP Virus, ‘Dramatic Inflammatory Response’: Preprint Study
epoch times ^ | 12 Decenber A.D. 2021 | Melanie Sun

Posted on 12/12/2021 4:48:38 PM PST by lightman

Edited on 12/12/2021 4:53:43 PM PST by Admin Moderator. [history]

Human fat cells can be directly infected with the CCP (Chinese Communist Party) virus, providing an additional site for the virus to replicate, according to a group of Stanford researchers who set out to determine the COVID-19 risk posed directly by obesity.

According to the researchers mainly based at Stanford’s School of Medicine, studies have shown that fat cells can act as a reservoir for RNA viruses like influenza A and HIV. Their new research, which was released in an October preprint and is awaiting peer-review, suggests that the same is occurring with the CCP virus, which causes the disease COVID-19.

Overweight and obese individuals are known to be at higher risk of COVID-19 infection, severe illness, and death. However, the direct contribution of fatty tissue, also known as adipose tissue, to severe disease is still not well understood given the long list of comorbidities associated with obesity and COVID-19, like hypertension and metabolic disease.

According to the study, researchers confirmed they found SARS-CoV-2, another name for the virus, directly infecting fatty tissue surrounding various organs in autopsies of European COVID-19 patients who had recently died.

The findings also describe, for the first time, experiments observing a “dramatic inflammatory response” in components of the fatty tissue consistent with that reported in patients with severe COVID-19 symptoms.

For the experiment, adipose tissue was taken from bariatric and cardiothoracic surgery patients and immediately exposed to SARS-CoV-2. Researchers observed different responses between components of the adipose tissue, which is made up of mature fat cells (also called adipocytes), pre-adipocytes (which turn into adipocytes), and various types of immune cells.

In these lab exposures, SARS-CoV-2 was also found to replicate in adipocytes, and although not much inflammation was observed directly in these cells, their infection drove a strong inflammatory response in a subset of infected macrophage immune cells as well as, to a lesser extent, pre-adipocytes, which did not become infected.

The findings, if approved by peer-review despite a lack of samples from lean control subjects and related issues, would provide some evidence that infected fatty tissue likely contribute to the secretion of substances that boost the inflammatory reactions contributing to severe COVID-19.

“Whatever happens in fat doesn’t stay in fat,” Philipp Scherer, who studies fat cells at UT Southwestern Medical Center in Dallas but was not involved in the research, told The New York Times of the implications of the findings. “It affects the neighboring tissues as well.”

Scherer added that the indications from the lab research still need to be compared with the responses occurring directly in fatty tissue as arranged in the human body (in vivo studies).

Study co-author Dr. Catherine Blish from the Stanford University School of Medicine told the New York Times that the results show that processes in human fatty tissue “could well be contributing to severe disease.”

“We’re seeing the same inflammatory cytokines that I see in the blood of the really sick patients being produced in response to infection of those tissues,” she said.

Scientists had hope with this research that they might be able to find better ways to help treat overweight COVID-19 patients.

Authors say that the observations suggest that lysozyme therapy could help reduce SARS-CoV-2 levels in adipose tissue, a step towards reducing severe disease. Lysozyme is a natural enzyme found in secretions such as tears, saliva, and milk that weakens cell-walls.

Obese patients are an ongoing a concern for medical staff, given their increased rates of requiring ventilator use, and doubled risk of admission to the ICU among younger obese patients under 60.

“Collectively, our data implies that infection in adipose tissue may partially explain the link between obesity and severe COVID-19,” the authors wrote. “More efforts to understand the complexity and contributions of this tissue to COVID-19 pathogenesis are warranted.”

TOPICS: Culture/Society; News/Current Events
KEYWORDS: bodyfat; cells; chinavirus; comorbidity; coupflu; covid; covid1984; obesity; research; virus
More evidence that lockdowns KILL.
1 posted on 12/12/2021 4:48:38 PM PST by lightman
[ Post Reply | Private Reply | View Replies]

To: lightman

8m18s in for BBC’s conclusion - no surprise for guessing what it is:

AUDIO: 9min: 12 Dec: BBC World Service “More or Less”: Does catching covid give you more immunity than being vaccinated?
Presenter: Tim Harford
Immunity to Covid-19. We’ve all been hoping to develop it ever since the virus emerged two years ago. Since then, a race to vaccinate the world has begun in earnest, with many countries rolling out booster shots in response to the rise of the Omicron variant. Health officials and scientists agree that vaccines are the safest way to develop immunity to the disease.

But when US Congresswoman Nancy Mace took to Fox News recently, citing a study showing a whooping 27 times better immunity from natural infection than vaccination, we thought we’d better investigate. How did this study arrive at this number, and is it a fair representation of its findings?

2 posted on 12/12/2021 4:53:34 PM PST by MAGAthon (y)
[ Post Reply | Private Reply | To 1 | View Replies]

To: lightman

“Obese patients are an ongoing a concern for medical staff, given their increased rates of requiring ventilator use, and doubled risk of admission to the ICU among younger obese patients under 60.”

If this thing were really about health, our authorities would be fat shaming 24/7 and would have been doing so for a while.

3 posted on 12/12/2021 5:06:01 PM PST by cdcdawg (Let's Go, Brandon!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: lightman

not sure if one can blame fatty livers or fatty hearts on lockdowns ;)

To add to the speculation about fat’s involvement:

” White women with high body mass indexes (BMIs) had more fat around their hearts than black women with the same BMI. Meanwhile, black women with large waistlines had more fat around their hearts than white women with similar amounts of belly bulge.

“In other words, a high BMI was more dangerous for white women, and carrying a spare tire was more dangerous for black women, says senior author Samar El Khoudary, PhD, associate professor of epidemiology at Pitt Public Health.

“Additionally, the study identified another danger specific to black women with large waistlines: Their cardiovascular fat tended to be even closer to their hearts than the type accumulated by white women with high BMIs. The closer fat is to the organ, says El Khoudary, the more it can damage heart tissue with its inflammatory proteins.”

4 posted on 12/12/2021 5:27:03 PM PST by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
[ Post Reply | Private Reply | To 1 | View Replies]

To: lightman

Great. My fat and I have been such fast friends for so very long, and now it’s revolting?

5 posted on 12/12/2021 5:33:03 PM PST by null and void (Newspapers, The Prints of Lies)
[ Post Reply | Private Reply | To 1 | View Replies]

To: lightman

Obesity kills and it’s been an evil thing for it to be mainstreamed as acceptable. Big boned or plump when old is different but we have pre-teens thinking it’s cool to be “thick” with very little if any activity.

All part of the long game of the communists I think. MTV made “thick” and “baby got back” a fad.

6 posted on 12/12/2021 6:25:57 PM PST by Pollard (PureBlood --
[ Post Reply | Private Reply | To 1 | View Replies]

To: lightman

“Human Fat Cells Host CCP Virus”
and sugar feeds it.

7 posted on 12/12/2021 7:28:45 PM PST by conserv8 (Always something hungry for something out there. Be careful.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: conserv8

Cut dem carbs!

8 posted on 12/12/2021 7:43:09 PM PST by lightman (I am a binary Trinitarian. Deal with it!)
[ Post Reply | Private Reply | To 7 | View Replies]

To: lightman


9 posted on 12/12/2021 9:05:38 PM PST by sauropod (Meanie Butt Daddy - No you can't)
[ Post Reply | Private Reply | To 1 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794 is powered by software copyright 2000-2008 John Robinson