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Study shows dramatic decline in effectiveness of all three COVID-19 vaccines over time
LA Times via Yahoo ^ | November 4, 2021 | by Melissa Healy

Posted on 11/05/2021 11:17:00 AM PDT by Oldeconomybuyer

As the Delta variant became the dominant strain of coronavirus across the United States, all three COVID-19 vaccines available to Americans lost some of their protective power, with vaccine efficacy among a large group of veterans dropping between 35% and 85%, according to a new study.

Researchers who scoured the records of nearly 800,000 U.S. veterans found that in early March, just as the Delta variant was gaining a toehold across American communities, the three vaccines were roughly equal in their ability to prevent infections.

But over the next six months, that changed dramatically.

By the end of September, Moderna’s two-dose COVID-19 vaccine, measured as 89% effective in March, was only 58% effective.

The effectiveness of shots made by Pfizer and BioNTech vaccine, which also employed two doses, fell from 87% to 45% in the same period.

And most strikingly, the protective power of Johnson & Johnson's single-dose vaccine plunged from 86% to just 13% over those six months.

The findings were published Thursday in the journal Science.

The three vaccines held up better in their ability to prevent COVID-19 deaths, but by July — as the Delta variant began to drive a three-month surge of infections and deaths — the shots' effectiveness on that score also revealed wide gaps.

(Excerpt) Read more at news.yahoo.com ...


TOPICS: Culture/Society; Government; News/Current Events; Politics/Elections
KEYWORDS: china; covid; faucivirus; fearporn; kungflu; notarealvaccine; va666ine; vaccine; vaccines; vaxholes; vaxzis; virus
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1 posted on 11/05/2021 11:17:00 AM PDT by Oldeconomybuyer
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To: Oldeconomybuyer
Will Joe Biden follow the science, as laid out in Science magazine?
2 posted on 11/05/2021 11:21:22 AM PDT by Pearls Before Swine (FJB/LGB (Let's Go, Brandon!))
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A strong argument for two or perhaps three boosters a year.


3 posted on 11/05/2021 11:21:50 AM PDT by JonPreston (Q: Never have so many, been so wrong, so often)
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To: Oldeconomybuyer

A couple UK studies indicate efficacy is even lower......


4 posted on 11/05/2021 11:21:55 AM PDT by cranked
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To: Oldeconomybuyer

No wonder there was a jump in cases of covid.....add in all those coming over the border......all data is outdated and was from the get go.


5 posted on 11/05/2021 11:22:57 AM PDT by caww ( )
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To: cranked

If the vaccines work, why aren’t they working?

Same for masks.


6 posted on 11/05/2021 11:23:44 AM PDT by Oldeconomybuyer (The problem with socialism is that you eventually run out of other people's money.)
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To: Oldeconomybuyer

Now you know why the CDC tested natural immunity only against people vaccinated in the most recent two months.


7 posted on 11/05/2021 11:24:25 AM PDT by alternatives? (The only reason to have an army is to defend your borders,)
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To: Oldeconomybuyer
Ya know I wonder? Could injecting graphine oxide many particles spliced with virus DNA like this vaccine just trigger a reaction across the board with the immune system which then Peter's out? Immune responses are not temporary. Something else is going on.

Sounds more to me like the vaccine is the disease and it takes your body six months to get rid of it. That's why you need boosters every six months. They have to keep giving you a disease to look for the immune response for the disease. It's a self perpetuating con job.

8 posted on 11/05/2021 11:24:40 AM PDT by blackdog (Jab Dodger. )
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To: Oldeconomybuyer

Dang, that manufactured kungflu virus that China unleashed onto the world sure is formidable.


9 posted on 11/05/2021 11:24:42 AM PDT by Kevmo (I’m immune from Covid since I don’t watch TV.🤗)
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To: Oldeconomybuyer

Yup. Slow murder is a bitch aint it? Hence, the booster shot!


10 posted on 11/05/2021 11:24:50 AM PDT by max americana (FIRED LEFTARD employees at our office every election since 2008 and enjoyed seeing them cry.)
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To: Oldeconomybuyer

I read about it in the paper, heard it on the radio long ago. They call it “Planned Obselence.”


11 posted on 11/05/2021 11:26:22 AM PDT by granite (The heart of the wise inclines to the right, but the heart of the fool to the left.Ecclesiastes 10:2)
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To: Oldeconomybuyer

12 posted on 11/05/2021 11:28:52 AM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: Oldeconomybuyer

Bump for later


13 posted on 11/05/2021 11:29:09 AM PDT by 4Liberty (Let's go Brandon 👏 ...👏 ...👏👏👏 https://youtu.be/qr_F_XQrukM?t=1)
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To: granite

What happened to the dialog that ‘Delta is code phrase for the adverse vaccine effects’


14 posted on 11/05/2021 11:29:17 AM PDT by George from New England
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To: Oldeconomybuyer

I guess even reporters are becoming more honest as the clot-injection comes for them.


15 posted on 11/05/2021 11:31:35 AM PDT by WMarshal ("Those who would give up essential liberty, to purchase a little temporary safety, deserve neither.")
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To: Oldeconomybuyer

Covid: How long does vaccine based immunity last? by Sebastian Rushworth, M.D.

It’s unfortunate that the drug companies decided to end their trials early, by giving active covid vaccine to the members of the placebo group after just a few months. It means that there is no long term follow-up of the covid vaccines from randomized trials, and there never will be.
This means that we are instead forced to rely entirely on observational data as we try to understand how safe and effective the vaccines are over the longer term.

That is why a recent study out of Sweden is so very interesting. It is currently available as a pre-print and can be found here. The purpose of the study was to determine how effective the vaccines are at protecting against covid over the longer term (i.e. after more than a few months). This was a registry based study, so it’s not surprising that it is coming out of Sweden. Sweden is generally acknowledged as being better than any other country at collecting and sorting large quantities of population data and using it to produce these types of studies.

The authors of the study began by identifying all people residing in Sweden who had been fully vaccinated against covid-19 by late May 2021. At that time, three different vaccines were being used in Sweden: Moderna, Pfizer, and AstraZeneca. The vaccinated people were then matched individually against people of the same age and gender, and living in the same municipality, who hadn’t been vaccinated. In total, 1,684,958 individuals were included in the study. They were followed until October to see if they developed covid-19.

So, what did the study show?

As would be expected, the vaccines were very effective at preventing symptomatic covid around two months out from vaccination.

This is what the randomized trials showed, and it’s the reason the vaccines were approved for use. Overall, the reduction in relative risk at 31-60 days out from vaccination was 89%.

However, after those first two months, there was a rapid decline in efficacy. At four to six months, the vaccines were only reducing the relative risk of infection by 48%!

This is pretty interesting when we consider that governments had initially set the bar for approving the vaccines at a 50% relative risk reduction. So, if the trials had been required to run for six months before presenting results instead of only running for two months, then the vaccines would have been considered too ineffective to be worth bothering with, an would never have been approved.

Well, that’s not quite true. One vaccine did still provide a better than 50% relative risk reduction at six months - the Moderna vaccine. At four to six months, the relative risk reduction with the Moderna vaccine was 71%. Pfizer was at the same time point only offering a 47% reduction in risk, and AstraZeneca was at that point not doing anything whatsoever to lower risk.

It makes sense that the Moderna vaccine would offer better protection than the Pfizer vaccine. Although the vaccines are virtually identical, the dose in the Moderna vaccine is three times higher. This is likely the reason why Moderna has been associated with much higher rates of myocarditis, which is why it is no longer approved for use in people under the age of 30 here in Sweden.

So, if governments hadn’t been so hasty to get the vaccines out, and had demanded six months of follow-up rather than two, only the Moderna vaccine would ever have been approved in the first place.

When we go further out than six months, things get even more depressing. By the nine month mark, the Pfizer vaccine is no longer offering any protection whatsoever against symptomatic covid-19. Unfortunately, nine month out data isn’t offered for the Moderna vaccine due to the small number of people for whom that information is currently available, but at six months out, the Moderna vaccine’s ability to prevent symptomatic covid-19 had dropped to only 59%. So there is a continuous decline in effectiveness at each time point measured even for the Moderna vaccine, without any sign of leveling off.

What about if we look at sub-groups, such as the elderly, who are by far the most at risk from covid-19, and therefore potentially have most to gain from vaccination?

People over the age of 80 initially show a good response to the vaccine, with a 73% reduction in relative risk of disease at one to two months out from vaccination. However this drops to only 50% at two to four months, and by six months there is no benefit whatsoever. Even for the middle aged (50-64 years), who have better functioning immune systems and who should therefore respond more strongly to the vaccines, the vaccines are completely ineffective at preventing symptomatic disease by the four to six months mark.

The only group for whom the vaccines are more than 50% effective by the four month mark is people under the age of 50 (for whom effectiveness at four to six months is 51%).

Of course, how good the vaccines are at preventing symptomatic disease isn’t really what matters, if by symptomatic disease we usually mean something more akin to the common cold than to the Spanish flu. What really matters is how good the vaccines are at preventing serious disease. So, let’s look at that.

At one to two months out from vaccination, the vaccines provided a 91% reduction in risk of hospitalization or death. By four to six months, that had dropped to 74%. And from six months out, the reduction was down to 42%, although the difference between the vaccinated and unvaccinated group was no longer statistically significant. In other words, at the six month time point it was no longer possible to detect a statistically significant effect of vaccination on risk of hospitalization or death.

As I see it, there are two possible explanations for the rapidly declining effectiveness of the vaccines. The first is that it’s due to the limited immunity produced by the vaccines themselves, and the second is that it’s due to the continued evolution of the virus and in particular the rise of the delta variant.

If the second reason is true, then there is no reason whatsoever to give people boosters, because the boosters won’t do anything to improve immunity.

If the first reason is true, then there is a case to be made for boosters, although it feels pretty absurd to give everyone a booster every four months to protect against a virus that for most people is little more than a cold, that 99,8% of infected people will survive, and for which there is now massive natural population immunity, thanks to all the people who have already had covid.

Unlike the short-term protection offered by the vaccines, the protection generated by infection has been shown to be both durable and broad, in spite of junk science claims to the contrary produced by the CDC. There is however a pretty good case to be made for regular boosting of the multi-morbid elderly every four months, preferentially with the Moderna vaccine.

At one to two months out from vaccination, the vaccines provided a 91% reduction in risk of hospitalization or death. By four to six months, that had dropped to 74%. And from six months out, the reduction was down to 42%, although the difference between the vaccinated and unvaccinated group was no longer statistically significant. In other words, at the six month time point it was no longer possible to detect a statistically significant effect of vaccination on risk of hospitalization or death.

As I see it, there are two possible explanations for the rapidly declining effectiveness of the vaccines. The first is that it’s due to the limited immunity produced by the vaccines themselves, and the second is that it’s due to the continued evolution of the virus and in particular the rise of the delta variant. If the second reason is true, then there is no reason whatsoever to give people boosters, because the boosters won’t do anything to improve immunity.

https://sebastianrushworth.com/2021/11/05/covid-how-long-does-vaccine-based-immunity-last/


16 posted on 11/05/2021 11:32:15 AM PDT by Grampa Dave (Ramp it up!: Reclaim America Movement Party! (RAMP!!!!!)
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To: Oldeconomybuyer

The real news is that the LA Times is reporting this news.


17 posted on 11/05/2021 11:33:01 AM PDT by rightwingcrazy (;-,)
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To: cranked

Swedish study across 840,000 was worse still.


18 posted on 11/05/2021 11:33:25 AM PDT by Uncle Miltie (Who is John Galt?)
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To: Oldeconomybuyer

As someone who had the China Virus and completely recovered, I’m glad I have natural immunity.


19 posted on 11/05/2021 11:33:25 AM PDT by Signalman
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To: Oldeconomybuyer

How else could they control your freedom unless you need a current booster every 6 months…???

No booster, no freedom. Compliance.


20 posted on 11/05/2021 11:34:26 AM PDT by aMorePerfectUnion (Fraud vitiates everything ᡕᠵ᠊ᡃ࡚ࠢ࠘ ⸝່ࠡࠣ᠊߯᠆ࠣ࠘ᡁࠣ࠘᠊᠊ࠢ࠘𐡏⁻ )
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