Posted on 11/05/2021 8:40:55 AM PDT by SeekAndFind
Thursday was a rough day for Moderna shares after the company released revenue figures and FY guidance that deeply disappointed Wall Street expectations (potentially destroying the reputation of financier Steve Weiss, arguably Moderna's biggest promoter on Wall Street, in the process). But on Friday, Pfizer - Moderna's biggest rival - rubbed Moderna's nose in it by announcing a revolutionary new oral COVID antiviral similar to the Merck 'miracle pill' that won approval from UK regulators yesterday.
The news sent Pfizer's stock surging, while Moderna and Merck shares tumbled, during premarket trade. Pfizer shares were trading up 11%+:
The key takeaway from the Pfizer announcement is this: Pfizer said studies showed its COVID-19 pill reduced hospitalizations and deaths in high-risk patients by 89%. That's even higher than the 50% reduction in hospitalizations and deaths shown by the Merck pill. Again, like Merck, Pfizer said that it was no longer taking new patients in a clinical trial of the treatment "due to the overwhelming efficacy" of the drug, which it now plans to submit its findings to the FDA for emergency authorization (just like Merck is doing). Yesterday, Merck won approval for its new COVID antiviral, molnupiravir, from regulators in the UK, and it's pushing to wrack up as many EUAs as possible from regulators from all over.
Pfizer is already planning to seek approval emergency approval from the US government because, according to the numbers, its drug is even more effective than molnuiravir. According to the headline numbers, Pfizer's new antiviral is even more effective than the rival pill from Merck. Pfizer’s pill, which will be sold under the brand name Paxlovid, cut the risk of hospitalization or death by 89% when taken within three days after symptoms emerge (the number for Merck's drug was it needed to be taken within 5 days of infection).
“The results are really beyond our wildest dreams,” said Annaliesa Anderson, a Pfizer executive who led the drug’s development. She expressed hope that Paxlovid “can have a big impact on helping all our lives go back to normal again and seeing the end of the pandemic.”
It's expected the new drug will be made available in the US at least but in limited quantities at first.
Criticisms have also been made about the cost of molnupiravir, and Pfizer CEO Albert Bourla already affirmed on CNBC that a course of the drug will cost insurers or customers around $700 (though the firm says it intends to sell the drug at a "discounted" prices to "poorer countries".
Per the NYT:
The U.S. government has been in negotiations with Pfizer for enough pills for 1.7 million courses of treatment, with an additional option for 3.3 million, according to a senior administration official. That is about the same quantity that the United States has ordered from Merck. The government expects to pay about $700 per treatment course for both drugs, the official said.
Both the Pfizer and Merck pills are both geared toward patients regarded as high-risk, including those above the age of 60 or with conditions like obesity that make them more susceptible to severe consequences from COVID.
But while experts again touted the drug's safety profile, several scientists have spoken out about potential safety risks tied to molnupiravir, the Merck drug.
Another important question: what does this mean now for President Biden's increasingly coercive vaccine mandate?
Very different chemical structures. Most likely, work by using the same mechanism of protease inhibition. Ivermectin would seem to be less toxic (no nitrogen structural blocks), the new pill probably inhibits protease at lower concentrations. Hopefully, side effects from the pill are not significant. Difference in cost should be substantial, which may explain negative publicity campaign against ivermectin. Would be interesting to compare both drugs in direct experiments, both in vitro and in vivo.
It will be marketed as that, but I had the impression this was the pill which induced RNA mutations.
but I had the impression this was the pill which induced RNA mutations.…
😱😱
They’re determined, aren’t they?
All you need to know is that Pfizer is state of the art in bribing politicians around the world.
They could be peddling sugar pills—would not matter.
Is our water supply safe?
It is a protease inhibitor like Ivermectin
>>What does it cost?<<
What’s in it? Ingredients please.
Pfizermectin?
*****************
No — Phizroxychloroquine.
It’s all about the money because Ivermectin is safe and works.
It was tested on “high-risk” covid patients. 27/385 (7%) of people in the control group were hospitalized and 7 (1.8%) died, compared to 3/389 (0.8%) hospitalizations in the treatment group and no deaths. So it might have presented 24 hospitalizations and 7 deaths.
It seems like covid wasn’t necessarily a death sentence to start with even in these high-risk people but the drug might be useful.
But then what’s the point of injection mandates? Doctors should be free (and encouraged) to treat cases with whatever effective medications are available.
Thanks for the info. Yes, I agree, the elderly probably, should co sider taking it if they have serious conditions, but they shouldn’t be forced to if they feel that they are OK with the very minor chance of dying from Covid. But, they should be offered the chance to take ivermectin as well, either with the vaccines or without,and started on it immediately upon getting covid in addition to giving them the covid meds that are bei g used in the hospitals for,covid. Where they are sick and elder,y, the docs should be throwing the whole enchilada at the virus, including using off label meds lik ivrrmectin. There is nothing wrong with using combos to fight off covid, but the left are such scumbags, who only want compliance. They refuse to allow ivermectin even though it is proving very effective overseas, and even here In The US (just ask the 130 congress-critters who took it when al. Of us are denied it)
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