Posted on 09/03/2021 7:52:10 PM PDT by Fractal Trader
A drug used to treat rheumatoid arthritis has been found to improve survival of hospitalized Covid-19 patients. The discovery comes from a study of over 1,500 Covid-19 patients in 12 countries and is being hailed as a significant breakthrough for treatment options for people who are severely ill with Covid-19.
Early on in the pandemic in February 2020, baricitinib was identified as a promising drug to treat Covid-19 by a company using artificial intelligence (AI) and machine learning to identify potential treatments for diseases. The drug, normally used to treat rheumatoid arthritis, was thought to have possible antivirus properties, but also known to be a strong inhibitor of inflammation. The researchers hoped that these anti-inflammatory properties would reduce the multi-organ damage often sustained by severely ill Covid-19 patients.
“Hospitalized patients with the SARS-CoV-2 infection (which causes Covid-19), often develop an intense hyperinflammatory state that can lead to dysfunction of multiple organs, including acute respiratory distress syndrome, septic shock and death,” said E. Wesley Ely, MD, MPH, Grant Liddle Professor of Medicine at Vanderbilt University Medical Center, one of the leaders of the study. “Despite treatment advances with remdesivir, dexamethasone and tocilizumab, reducing mortality among hospitalized patients remains a crucial unmet need,” added Ely.
(Excerpt) Read more at forbes.com ...
ping
Saves one in 20. Not even a 50/50 odds of it helping. Not statistically significant (a fraud)
Small world.
FTA....
.... The researchers found that baricitinib reduced deaths by 5%, saving 1 in 20 patients who would otherwise have died from Covid-19 within 60 days.
Crucially, the patients who benefitted the most from the drug were the most severely ill, including those on a bipap machine to help them breathe or high flow oxygen. In these more severely ill patients, the researchers found that 1 in 9 patients were saved who would have otherwise died.....
This is a different drug....
Baricitinib, sold under the brand name Olumiant among others, is a drug for the treatment of rheumatoid arthritis in adults whose disease was not well controlled by tumor necrosis factor inhibitors. It acts as an inhibitor of janus kinase, blocking the subtypes JAK1 and JAK2.Wikipedia
~~~~~
I wonder if they have similar properties.
Interesting timing coincidence ....
JAK inhibitors from Pfizer, AbbVie and Lilly hit with dreaded FDA heart safety, cancer warnings
....The FDA is requiring new heart safety and cancer warnings for Xeljanz, AbbVie’s Rinvoq and Lilly’s Olumiant, the agency said Wednesday. All three drugs belong to the same JAK inhibitor class of medicines, and they currently already bear boxed warnings about blood clots and lymphoma.
Thanks to the updated warnings, the FDA is pushing back the drugs’ place in the treatment sequence and is limiting their use in all approved indications to certain patients who have failed on or aren’t appropriate for treatment with TNF blockers. For AbbVie’s star immunology drug Rinvoq, the news prompted one influential analyst to dramatically lower his long-term sales expectations.....
(Remember when HCQ had heart warnings....but, FRAUDci, and the like?)
🤔
I suspect it’s a lot more expensive than Ivermectin.
Okay so the CDC and Pharma violated my trust again and and again with the entire plandemic (understatment of 2021 - trademark pending) and now they have to prove to me this new 'solution' is better than Ivermectin or HCQ. Those two have an excellent safety record and are saving lives around the world.
Release Ivermectin and HCQ and make baricitnib available. Then, patients can read the historic record for Ivermectin & HCQ (you know, not the new lies the FDA and CDC are telling us about these drugs) and we can compare their records to baricitinib.
If the FDA won't let us have safeter drugs like Ivermectin and HCQ, but will give us something with this inferior safety profile then there has to be a reason WHY, and I don't believe it is good.
They used a fake PCR and have denied dying people all treatments - why should I think they suddenly want to help us?
Baricitinib Uses, Side Effects & Warnings - Drugs.com
You may get infections more easily, even serious or fatal infections.
Before or during treatment with baricitinib, tell your doctor if you have signs of infection such as fever, chills, aches, tiredness, cough, skin sores, diarrhea, or burning when you urinate.
Tell your doctor if you've had or been exposed to tuberculosis, or if you recently traveled. Some infections are more common in certain parts of the world, and you may have been exposed during travel.
Tell your doctor if you have ever had:
a chronic infection or weak immune system;
active tuberculosis;
liver disease (especially hepatitis B or C);
kidney disease (or if you are on dialysis);
lung disease;
diabetes;
HIV or AIDS;
a stomach or intestinal problem such as diverticulitis or an ulcer;
a perforation (a hole or tear) in your stomach or intestines;
a blood clot;
cancer;
low white or red blood cell counts; or
if you have recently received or are scheduled to receive any vaccine.
Using baricitinib may increase your risk of developing certain cancers. Ask your doctor about this risk.
Tell your doctor if you are pregnant or breastfeeding.
Rummy Chick brought this up earlier,
Took four paragraphs to find out what it is.
baricitinib
and what good it does.
Saves 1 in 20 or 5%
Compared to Ivermectin
Saves about 70% or so or 14 in 20.
Big friggin whoop.
None of this has ever been about helping or saving anyone - quite the opposite.
It’s not if you are the 1 in 20.
there’s a logic to this - given severe inflammation is one of the killers of COVID19.
Another article about the Pneumonia Vaccine and COVID,
“ In summary, these researchers stated ‘the reduced risk of COVID-19 among PCV13 recipients, transiently attenuated by antibiotic exposure, suggests pneumococci may interact with SARS-CoV-2.’
Recently, a study published by Mayo Clinic researchers also reported a strong association between pneumococcal vaccination and protection against COVID-19.
Published in the journal Nature on February 26, 2021, this exploratory study analyzed immunization records from 137,037 individuals who received SARS-CoV-2 PCR tests.
This study found that polio, Haemophilus influenzae type-B, measles-mumps-rubella, Varicella, PCV13, geriatric Flu vaccine, and hepatitis A/hepatitis B vaccines administered in the past 1, 2, and five years were associated with decreased SARS-CoV-2 infection rates.
Furthermore, age, race/ethnicity, and blood group stratified analyses reveal significantly lower SARS-CoV-2 infection rate among black individuals who have taken the PCV13 vaccine, with a relative risk of 0.45 at the five year time horizon (n: 653, 95% CI (0.32, 0.64), p-value: 6.9e−05).
‘There are prior studies highlighting mechanisms of activation of broad immune signaling pathways by vaccines, which might also be providing protection against SARS-CoV-2. This nonspecific innate response conferring protection to other infections is termed as ‘trained immunity,’ concluded this study.
The Mayo Clinic trained immunity finding may help explain why children are seldom admitted to hospitals for COVID-19.”
Well, knock me over with a feather.
All these doctors and researchers are proving every day that they really know, at most, very little about this disease.
Or hydroxychloriquine or regeron.
Just about anything that can reduce severe inflammation would be helpful in treating the chinahvirus.
‘All these doctors and researchers are proving every day that they really know, at most, very little about this disease.’
exactly, which is why I don’t pay much attention to all of this drivel. It’s noise pollution, IMO.
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