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The Biopharmaceutical Industry Provides 75% Of The FDA's Drug Review Budget. Is This A Problem?
Forbes ^ | Jun 28, 2018 | John LaMattina

Posted on 08/24/2021 1:41:51 PM PDT by Vendome

Caroline Chen of ProPublica has written a provocative article challenging the objectivity of the FDA in its approval of new drugs. Entitled: “FDA Repays Industry by Rushing Risky Drugs to Market”, Chen contends that the agency is beholden to the biopharmaceutical industry which pays three quarters of the FDA’s budget used for the drug review process. This is an astounding number. Is any other federal agency supported to this extent by the industry it regulates? Given this level of support, one might assume that the FDA would bend over backwards to meet the needs of its financial backers.

"...this all began about 25 years ago, when the U.S. was facing a “drug lag”. Because of a lack of resources at the FDA, drugs were being approved at a much slower rate here than in Europe. More than half of all drugs approved in the U.S. had been approved in Europe more than a year earlier. "

To solve this problem, Congress enacted the Prescription Drug User Fee Act (PDUFA) of 1992–a mechanism whereby charges were levied on pharmaceutical companies for each new drug application (NDA) filed. The revenues, known as “user fees”, were used to hire 600 new drug reviewers and support staff. These new medical officers, chemists, pharmacologists, and other experts were tasked with clearing the backlog of NDAs awaiting approval. In fact, one of the biggest years of NDA approvals occurred in 1996 when the FDA approved 56 new products

(Excerpt) Read more at forbes.com ...


TOPICS: Business/Economy; Constitution/Conservatism; Culture/Society; News/Current Events
KEYWORDS: go; let; my; people
Fuller quote: "How did we ever get to the point where private industry is providing so much support for a federal agency? Actually, this all began about 25 years ago, when the U.S. was facing a “drug lag”. Because of a lack of resources at the FDA, drugs were being approved at a much slower rate here than in Europe. More than half of all drugs approved in the U.S. had been approved in Europe more than a year earlier. Patients, advocacy groups, pharmaceutical companies, and physicians were all concerned that important new medicines were being denied to Americans."

Demand created the problem and givernment trusted other men not to be self serving fiends...

More from the article: As a concession to agreeing to these “user fees”, the pharmaceutical industry was promised that the FDA would reduce review times of NDAs to 12 months for those that were considered “standard” applications and to 6 months for priority applications that involved significant advances over existing treatments. The PDUFA Act has since been repeatedly renewed with PDUFA VI passing last year. And, as would be expected, “user fees” have gone up over the years, from $208,000 per NDA in 1995 to a whopping $2,421,495 for fiscal year 2018. Keep in mind that the industry didn’t exactly have a choice in this matter. PDUFA was a decision by Congress to make the pharmaceutical industry pay for the work it was generating at the FDA–work being done to get new medicines to Americans. It wouldn’t be surprising to see Congress eventually transfer 100% of the costs of FDA reviews of NDAs to industry.

1 posted on 08/24/2021 1:41:51 PM PDT by Vendome
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2 posted on 08/24/2021 1:44:10 PM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: Vendome
" . . . the agency is beholden to the biopharmaceutical industry which pays three quarters of the FDA’s budget used for the drug review process."

This is crazy. Why aren't they budgeted in the normal way, through tax dollars? Why allow such an obvious potential for conflict of interest?
3 posted on 08/24/2021 1:44:56 PM PDT by Steve_Seattle
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To: Vendome

Propublica.

Leftist/commie as the day is long.


4 posted on 08/24/2021 1:44:58 PM PDT by ifinnegan ( Democrats kill babies and harvest their organs to sell)
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To: Vendome

The problem is the product testing is done under drug company contract.


5 posted on 08/24/2021 1:48:01 PM PDT by Brian Griffin
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To: Steve_Seattle

Government for sale.
Pay to play..... Rule #1


6 posted on 08/24/2021 1:50:41 PM PDT by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
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To: Steve_Seattle

The public was clamoring for drug approvals that made more sense.

Drugs in Europe had long been approved years before they could be approved in the USA and US citizens seeing positive results wanted drugs approved here as well and on the same time line.

The givernment couldn’t approve them fast enough with their budget limitations so they hatched this crazy partnership scheme with the BioPharma Industrial Complex and this is what we got.


7 posted on 08/24/2021 1:51:59 PM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: Brian Griffin

The drug companies are experts at lying and cheating and bribing politicians.

Otherwise they would be out of business.

Think of it as Big Pharma in action.


8 posted on 08/24/2021 1:54:41 PM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: Brian Griffin
The problem is the product testing is done under drug company contract.

Should clinical trials be done with public financing?

9 posted on 08/24/2021 2:13:46 PM PDT by corkoman
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To: Vendome

When submitting a medical device, pharmaceutical, IVD, etc. to the FDA for review the company doing the submission has to pay the FDA for their time. It has been that way for years.

The FDA reviews the data submitted to it, they do not collect the data themselves. Typically if a clinical trial is required those trials are run independently, not under the control of the manufacturer. Again the manufacturer must pay for the clinical trial but does not generate the results.

For example if our department generates a new product it undergoes trials at separate locations, generally at least two institutions are involved. Our department does not interfere with the clinical trials in any way. Then an independent contractor assembles and submits all manufacturing and clinical data, paid for by our company.

Yes, the FDA gets user fees from manufacturers, but imagine if they did not. The taxpayer would foot the bill for private gain.


10 posted on 08/24/2021 2:18:26 PM PDT by packagingguy (Kit)
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To: Vendome

Corporations provide 75% of campaign cash on average for all political candidates and institutions. Where is the news in this?


11 posted on 08/24/2021 2:21:35 PM PDT by entropy12 (President Trump was the best president in my life time of 81 years and counting..)
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To: Vendome

Money’s not all Big Pharma provides, is it...

Guess who works at the FDA?

Former Big Pharmers.

Can you say “revolving door”, boys and girls?

I knew you could!


12 posted on 08/24/2021 2:24:34 PM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: mewzilla

Money’s not all Big Pharma provides, is it...

Guess who works at the FDA?

Former Big Pharmers.

It is the very definition of corporatism or to be more vernacular fascism.


13 posted on 08/24/2021 2:29:07 PM PDT by Flick Lives (We may or may not have reached herd immunity, but we've definitely achieved herd stupidity.)
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To: Flick Lives

Yup.

We are in such deep doo doo.


14 posted on 08/24/2021 2:32:09 PM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: Vendome

Duh! big pharma pays everyone off


15 posted on 08/24/2021 2:53:05 PM PDT by Machavelli (True God)
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To: Machavelli

Follow the science!!

Follow the money!!

Lmao. Our country is utterly corrupt. I’ve come to accept it and honor no previous loyalty.


16 posted on 08/24/2021 3:11:26 PM PDT by americas.best.days... ( Donald John Trump has pulled the sword from the stone.)
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