Posted on 12/31/2020 12:56:46 PM PST by aimhigh
While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to treat hospitalized patients. One of these treatments, remdesivir, is the first and only antiviral agent of its kind that the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19.
Research at the University of Cincinnati, however, contends that this antiviral drug is being used too indiscriminately when treating patients hospitalized with the virus. The study is published in the journal Fundamental & Clinical Pharmacology.
. . .
In the UC study, lead author Bingfang Yan, a pharmaceutical scientist, and his UC graduate students Yue Shen and William Eades, found that the drug permanently stops the activity of an enzyme called CES-2, which is found in the intestine, liver and kidney and is needed for the breakdown of many medications.
"This enzyme normally breaks down and activates medicines in certain antivirals or inactivates other medicines such in certain anticoagulants," says Yan, professor at the James L. Winkle College of Pharmacy. On the other hand, he says this breakdown increases the toxicity of many more medications such as with heart medicines and anticancer drugs.
An antiviral is a drug against viruses and an anticoagulant is a drug that hinders the clotting of blood. What further complicates the issue, Yan says, is that when delivered through an IV, remdesivir does not treat the virus unless the body has additional specific enzymes, which are not found in all patients. It can also cause other antiviral drugs, such as those used for HIV/AIDs and hepatitis C, to not work properly.
Drug-drug interactions.
I believe Fauci endorsed remdesivir.
Bingfang Yan. There’s someone who immediately engenders trust with Chinavirus.
Can’t help it. I’m a little concerned that the lead researcher’s name is Bing Fang Yang. Just a passing thought.
Agreed. 2 of the 3 researchers are Chinese nationals. Bot feeling inspired by that fact.
Why the reliance on an 80 year old Doctor who hasn’t carried a PATIENT caseload in 30-40 years, or longer?
He is a PUPPET of the State.
GO AWAY Fauci.
I am told that in my area this is the only So called Covid drug that is being used in the local hospital.
If you dug into the studies then they showed that this drug did not work.
No wonder people are dying. That is by design. And they also have to be able to scare people into taking the vaccine.
eli lilly bamlanivimab shows some promise but there is a narrow window to use it.
Remdesivir saved my boyfriend’s life.
“Emergency Use Authorization” to start using a new treatment cannot be given if there is already a safe and effective treatment, hence the hostility by the research community to any idea that an existing drug will work.
https://www.fda.gov/vaccines-blood-biologics/vaccines/emergency-use-authorization-vaccines-explained
Oh yes, We believe this 100%
Bullshitte
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