Over 100,000 Americans Have Volunteered For Covid-19 Vaccine Trial In Less Than Two Weeks

Forbes ^ | 07/21/2020 | Daniel Cassady

[SeekAndFind]

About 138,600 Americans have already volunteered to participate in clinical trials for a Covid-19 vaccine less than two weeks after the launch of a national effort to sign up a total of 120,000 participants to help test four vaccines beginning this fall, according to the National Institute of Allergy and Infectious Diseases.

KEY FACTS

* In an effort to recruit the vast number of volunteers needed to test potential vaccines, NIAID launched the website for the Covid-19 Prevention Network July 8, where volunteers can sign up.

* The Prevention Trials Network was created by combining four already existing clinical trial networks funded by the NIAID.

* There will be over 100 testing sites across the U.S. with the possibility of sites opening internationally as well.

* After registering on the website, volunteers are given a questionnaire that’s designed to evaluate how likely they are to become infected with the virus and whether they are eligible for the clinical trials.

* A potential vaccine developed by Moderna, which recently published the results of a promising 45-person trial, is expected to be the first vaccine tested in a large Phase 3 trial. Other vaccines in line for Phase 3 trials have been developed by AstraZeneca, Inovio and Johnson & Johnson.

KEY BACKGROUND

According to the Covid-19 Prevention Network website, most studies will require volunteers to visit a research site at least 10 times over one or two years where they will be injected with either a potential vaccine or a placebo. Researchers won’t infect volunteers with Covid-19 but rather will give volunteers the vaccine and see if that prevents them from becoming infected.

[HangnJudge]

I am over 65, male, overweight, preconditions, and work in a hospital with 15 COVID cases in it, right now. Struggling with desire to quit. My wife's situation is even more tenuous than mine. Darned toot’n I'd consider a vaccine trial.

[Bommer]

(Disclaimer: May cause sudden rectal bleeding, terminal impudence through sterilization, cancer, heart attacks, homoerotic feelings towards children, enlarged breast for men, no breast for women, sudden projectile vomiting, paralysis, terminal memory loss, suicidal depression)

Ask your doctor (who we paid off) if COVIDist is right for you?

[FamiliarFace]

***From what I understand, the trials at this point occur after the vaccine has been tested on animals and small human subjects to ensure it is being given at a dose that is safe and will work.***

I would be surprised if those animal trials have taken place. In the old days of the 1980s, those lab animal trials took months of prep, sometimes nearly a year.

Also, what did you mean by small humans?

[married21]

I think they are heroes. They volunteered to help. Some people give blood, some people work at food banks, some people do this form of self-sacrificing effort to help. I don’t understand mocking people on this at all.

[ConservaTexan]

These vaccines are being rushed to market. The usual "safeguards" have been removed, suspended or altered. "Informed people" are few and far between in this country. I seriously doubt more than 2% of these volunteers have heard of thalidomide, which was FULLY tested and approved under normal pharmaceutical testing requirements.

I'm sure Bill Gates is thrilled at this news. You don't bother me. Personal injury attorneys are salivating watching these products being rushed and eventually forced on the American people. Just curious, have you volunteered for these new vaccine trials?

[hawkaw]

A small number of humans.

Based on what I have read, the investigators have given the vaccines too animals.

[hawkaw]

My understanding is these vaccines are still having to go through the usual rigorous testing. What has sped up is the companies may do two phases at the same time. Also, what had sped up is creating the vaccines for distribution before the testing has been completed in order to have them ready to go once testing and approval is complete. It’s all part of Trump’s plan that I support.

[cgbg]

The pro-vaccine propagandists are trying to ignore the lack of long-term testing and review since that will not be possible with any new vaccine.

Do you feel lucky?

Well, do ya?

[cnsmom]

If we can’t trust the tests then the vaccine is worthless and risky.

[matt04]

Yep. Sure, let me trust this fast-tracked vaccine so I can get back to normal again, because that is the way the Gov said we had to do things.

[FamiliarFace]

In my earlier years, I was part of a vaccine trial on mice (as a lab tech). IIRC we had to introduce the vaccine at various dosages as well as different timelines, so that when we infected them we could count how effective the vaccine was at those various dosages and various start dates. I recall that it may have even been close to a year before we actually infected these mice, but maybe it was only 6 months worth of prepping the mice. Now this was for a bacteria, not a virus, for that particular trial, but I would assume that viruses may be handled in a similar way. I worry that we haven’t given our test animals enough time in these trials, but I guess that’s not for me to say. I don’t know one way or the other. I’m just saying, I have concerns, and I think they are valid concerns.

Mask wearers say let’s be safe, not sorry. I think testing vaccines certainly falls into that category.

[Fury]

Re: 45 - Thanks for the post. I understand your position better.

I needed to look around to see where you can volunteer.But I found the article and have now volunteered. If selected, I woulds review all information, pro and con, and make an informed decision on whether to continue further.

[LegendHasIt]

A couple of little factoids about Moderna, the Company that is making this ‘vaccine”:

Here are a couple of interesting little factoids:

Moderna has NEVER produced any drugs that have actually made it to market. They closest they have come is a collaboration with Astra Zeneca that is still being tested (AZD8601). And IT must be injected directly into the heart to MAYBE work

Th main business they are in is stock manipulation.

The name Moderna doesn’t have anything to do with the word “modern” as I first assumed... It is for “MODifiEd RNA. They aren’t trying to make drugs... they are working on genetic modification.

I wouldn’t want to call anyone who wants to be a guinea pig for this a fool....

But I can’t think of anything better to call them.

[Monty22002]

How did I know this thread would start with a bunch of freepers bitching and moaning and then turn more reasonable when actual people show up?

[Lou L]

How will they determine if this will prevent them from becoming infected unless they try to infect them? Isn’t that part of testing a vaccine to see how much (dosage wise) is needed to thwart the virus?

I do think that's a problem for this clinical trial. Administering a vaccine and then observing whether or not that patient becomes infected seems like a huge variable to me.

What if one patient on placebo has a "high risk" profile in terms of their personal behavior? What if they frequently use mass transit, frequents gyms, bars, or other high-volume areas, regularly meets friends and acquaintances, and become infected with SARS Cov-2? What if another patient administered with the live vaccine has a low-risk profile; i.e., constantly wearing masks, washes hands religiously, regularly meets with family through Zoom calls, stays at home, etc? Is that a fair comparison?

[FamiliarFace]

Thank you.