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Scientists hail dexamethasone as 'major breakthrough' in treating COVID-19 [and it's cheap!]
www.reuters.com ^ | 06-16-2020 | Kate Kelland, Alistair Smout

Posted on 06/16/2020 7:01:52 AM PDT by Red Badger

Dexamethasone, a cheap and widely used steroid, has become the first drug shown to be able to save lives among COVID-19 patients in what scientists hailed as a “major breakthrough”.

Results of trials announced on Tuesday showed dexamethasone, which is used to reduce inflammation in other diseases, reduced death rates by around a third among the most severely ill COVID-19 patients admitted to hospital.

The results suggest the drug should immediately become standard care in patients with severe cases of the pandemic disease, said the researchers who led the trials.

“This is a result that shows that if patients who have COVID-19 and are on ventilators or are on oxygen are given dexamethasone, it will save lives, and it will do so at a remarkably low cost,” said Martin Landray, an Oxford University professor co-leading the trial, known as the RECOVERY trial.

“It’s going to be very hard for any drug really to replace this, given that for less than 50 pounds ($63.26), you can treat eight patients and save a life,” he told reporters in an online briefing.

(Excerpt) Read more at reuters.com ...


TOPICS: Business/Economy; Culture/Society; Foreign Affairs; Government
KEYWORDS: ards; chinavirustreatment; cytokinestorm; dexamethasone; hcqzpaczinc; steroid
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To: BushCountry; LouieFisk
Now if we can prevent ... governors from sticking Covid positive patients in nursing homes there will be no serious second wave.

Strip their sovereign immunity for violating 18 USC § 241 and 18 USC § 242, open the floodgates for a thousand wrongful death civil lawsuits, and no future governor will risk everything he or she owns and their coveted civil service pension.

While we're at it criminal charges are in order.

LouieFisk found this gem:

There’s what’s called “depraved heart” murder - from Findlaw cuz I don’t trust my memory right now:

“Often the intent to kill (or malice aforethought) element of murder can be satisfied by showing that the defendant showed extreme indifference to human life. These are also known as “depraved heart” murders.

Acting with extreme recklessness and knowing that act is dangerous to human life (i.e., firing through the floor of your third-story apartment) and ending a human life may satisfy this intent element, even if the person never intended to kill anyone. This has been argued in fatal DUI cases in which the driver was far too intoxicated to form any intent.”

It seems to me that forcing nursing homes to accept patients who are infected or still infectious, while safe alternatives were available, would be an act of a "depraved heart".

Bring federal depraved heart murder charges against any governor who ordered infectious patients into facilities with the very most vulnerable people, and any minion who executed those orders.

41 posted on 06/16/2020 7:56:24 AM PDT by null and void (2020 is one big Babylon Bee article)
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To: gas_dr

I had severe lung congestion and shot of the hydrodcortisone—I believe it was—reduced the inflammation inside of 3 hours. Astounding.


42 posted on 06/16/2020 8:07:37 AM PDT by chiller (Davey Crockett said: "Be sure you're right. Then go ahead'. I'm going ahead.)
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To: the OlLine Rebel

1. Do we know if Lupus patients or others that take the drug for malaria prevention are less susceptible to Covid? A really simple question that could have answered quickly.

2. Are the tens of thousands medical workers and others taking it preventatively less susceptible?

3. What non-bias study has been done with HCQ and Zithromax (Z-pack) along with Zinc if needed (not a cure, but preventative)?

4. How many studies been totally discredited within days of being released. The scientific community has lost all of it’s creditability.


43 posted on 06/16/2020 8:19:53 AM PDT by BushCountry (thinks he needs a gal whose name doesn't end in ".jpg")
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To: Red Badger

Oh my. Here we go again.


44 posted on 06/16/2020 8:24:41 AM PDT by Sequoyah101 (We are governed by the consent of the governed and we are fools for allowing it.)
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To: Guenevere; gas_dr
HCQ with zinc is an excellent prophylaxis

I work in physical rehab. 2 of my co-workers obtained HCQ easily through Rx. We can't obtain zinc! Shelves are bare, and zinc is the key.

45 posted on 06/16/2020 8:27:31 AM PDT by spankalib
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To: Mr Ramsbotham

You are correct. However ARDS is not pneumonia. That gets confused in the news. And is often misreported. Your experience makes you far more educated than the standard idiot covering medical news

The stitches on the fast ball is this study compares the efficacy of dexamethasone in particular with other steroids. Dex is more powerful and hence not used a lot precisely because of the immunosuppressant fear. Surviving sepsis campaign chose hydrocortisone as its steroid of choice and I suppose has been extrapolated to all critical situations.

This particular article is poorly reported on by the lay press and the actual study has a lot of medical nuance in it.


46 posted on 06/16/2020 8:33:10 AM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: spankalib

Its pretty easy to get zinc — I got a ton of it online.


47 posted on 06/16/2020 8:50:44 AM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: Red Badger

Dexamethasone reduced deaths by one-third in ventilated patients
...............
and by one fifth in other patients receiving oxygen only
.............
There was no benefit among those patients who did not require respiratory support.


48 posted on 06/16/2020 8:53:17 AM PDT by gandalftb
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To: BushCountry
1. Do we know if Lupus patients or others that take the drug for malaria prevention are less susceptible to Covid?

Yes.

That was the first clue pointing to HQC as a preventative and later a treatment for COVID-19.

3. What non-bias study has been done with HCQ and Zithromax (Z-pack) along with Zinc if needed (not a cure, but preventative)?

To the best of my knowledge, none, nor have any studies looked at Vitamins D and C in conjunction with the synergistic HCQ, azithromax and zinc cocktail.

4. How many studies been totally discredited within days of being released. The scientific community has lost all of it’s credibility.

I've long since lost count.

At least they've preserved their Agenda street cred...

49 posted on 06/16/2020 8:53:42 AM PDT by null and void (2020 is one big Babylon Bee article)
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To: FamiliarFace
How does the pharmacist know if you haven’t recently been diagnosed with lupus or rheumatoid arthritis?

He/she doesn't.

But the insurance companies will be all over the doctors for falsified medical records, state boards as well, I bet, especially in blue states.

50 posted on 06/16/2020 8:56:16 AM PDT by null and void (2020 is one big Babylon Bee article)
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To: nikos1121

the hydroxychloroquine might be equally as effective in higher doses than what is given.

~~~~~~~~~~~~~~~~~~~~~~~~~~~

Seems the hydroxy works best with those not criticially ill. Maybe this steroid helps those who are more critical? Steroids are tricky things.


51 posted on 06/16/2020 9:07:49 AM PDT by little jeremiah (Courage is not simply one of the virtues, but the form of every virtue at the testing point.)
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To: null and void

Even after the FDA announcement yesterday, that hydroxy is fine to use for chicomvirus?


52 posted on 06/16/2020 9:08:44 AM PDT by little jeremiah (Courage is not simply one of the virtues, but the form of every virtue at the testing point.)
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To: null and void

That is why you pay for it privately. I believe it is a relatively cheap medication. From what I understand. No insurance, cash basis, no one knows....kind of like what we always here from the left — a decision between a doctor and a patient is sacrosanct


53 posted on 06/16/2020 9:13:30 AM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: little jeremiah

What does a democrat governor care? The democrats need a devastated economy and a pile of bodies to stand on, the higher the pile the better, to get rid of Orange Man Bad!

For traitors contemplating the possibility of the noose, it quite literally is a mater of life and death.


54 posted on 06/16/2020 9:23:07 AM PDT by null and void (2020 is one big Babylon Bee article)
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To: gas_dr; little jeremiah; bitt
***Dex is more powerful and hence not used a lot precisely because of the immunosuppressant fear***

This was one of my first doubts when reading this; COVID is not just a cytokine inflammatory attack; it also involves a viral pathogen. My limited understanding is that steroids tend to strengthen or encourage pathogens in general.

That raises my other issue - that dexamethasone is an immunosuppressant; isn't that the opposite effect of what is desired? I can see this as a followup to an effective antiviral / antibiotic treatment, but as an initial attack on a potentially deadly disease - I am doubtful.

***This particular article is poorly reported on by the lay press and the actual study has a lot of medical nuance in it***

Indeed, I think this is part of the continuing attack on HCQ and Azithromycin. I was in the hospital last week and had a chance to talk to the infectious disease specialist... asked him if he prescribed HCQ (etc) for COVID; he said 'absolutely'! We both shared the shock that there were people who would let people die needlessly if it served political ends. A new age. 🤨

55 posted on 06/16/2020 9:29:12 AM PDT by Bob Ireland (The Democrap Party is the enemy of freedom.They use all the seductions and deceits of the Bolshevics)
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To: the OlLine Rebel

Lol

Did you forget the sarcasm tag? Or not particularly well read on the subject?


56 posted on 06/16/2020 9:29:23 AM PDT by zek157
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To: gas_dr

The pharmacists in my benighted state are under DIRECT orders to not dispense HCQ under penalty of license revocation.

Said order given by Gov Sisolak, who was caught hoarding HCQ for himself, his family and every convicted felon in prison.

Read that again. HCQ for incarcerated felons, but not for honest, hard working taxpayers!

If you were a pharmacist, would you dispense? I know, I know you know the order is at very best questionable and would never stand up in court, but do you want to spend years going before democrat judges and fighting in in higher and higher courts, while racking up immense legals bills with your career blocked to you and no viable source of income?


57 posted on 06/16/2020 9:33:01 AM PDT by null and void (2020 is one big Babylon Bee article)
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To: Red Badger

No telling how many years it will take to get approved for this use.


58 posted on 06/16/2020 9:44:54 AM PDT by LouieFisk
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To: LouieFisk

I believe it already is approved for lung and other respiratory problems................


59 posted on 06/16/2020 9:46:37 AM PDT by Red Badger (Always trust God............but wash your hands......................)
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To: Bob Ireland; gas_dr

Thanks for the detailed information.


60 posted on 06/16/2020 9:46:50 AM PDT by little jeremiah (Courage is not simply one of the virtues, but the form of every virtue at the testing point.)
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