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Locked on 05/23/2020 1:16:19 PM PDT by Jim Robinson, reason:
duplicate http://www.freerepublic.com/focus/f-news/3847897/posts |
Posted on 05/23/2020 11:26:42 AM PDT by LRoggy
BACKGROUND
Although several therapeutic agents have been evaluated for the treatment of coronavirus disease 2019 (Covid-19), none have yet been shown to be efficacious.
METHODS
We conducted a double-blind, randomized, placebo-controlled trial of intravenous remdesivir in adults hospitalized with Covid-19 with evidence of lower respiratory tract involvement. Patients were randomly assigned to receive either remdesivir (200 mg loading dose on day 1, followed by 100 mg daily for up to 9 additional days) or placebo for up to 10 days. The primary outcome was the time to recovery, defined by either discharge from the hospital or hospitalization for infection-control purposes only.
RESULTS
A total of 1063 patients underwent randomization. The data and safety monitoring board recommended early unblinding of the results on the basis of findings from an analysis that showed shortened time to recovery in the remdesivir group. Preliminary results from the 1059 patients (538 assigned to remdesivir and 521 to placebo) with data available after randomization indicated that those who received remdesivir had a median recovery time of 11 days (95% confidence interval [CI], 9 to 12), as compared with 15 days (95% CI, 13 to 19) in those who received placebo (rate ratio for recovery, 1.32; 95% CI, 1.12 to 1.55; P<0.001). The Kaplan-Meier estimates of mortality by 14 days were 7.1% with remdesivir and 11.9% with placebo (hazard ratio for death, 0.70; 95% CI, 0.47 to 1.04). Serious adverse events were reported for 114 of the 541 patients in the remdesivir group who underwent randomization (21.1%) and 141 of the 522 patients in the placebo group who underwent randomization (27.0%).
(Excerpt) Read more at nejm.org ...
Old Fart Power!!
Been taking D3, Zinc Sulfate and C every day for 6 weeks and i work in a very high risk environment.
OK so far...
Today i learned how to make my own Quinine.
Maybe this weekend i’ll make some....
https://www.youtube.com/watch?v=-W5wPNrCdJ4&list=PLiOdaKiVwGz0iflZ1JGiLn9mh14rKWZrI&index=46&t=0s
HEY!
I’m looking at you don’t let those eyes of yours wander son...
The politicization of coronavirus treatments is the single weirdest thing about the whole pandemic. That Red Team is rooting for one particular treatment, and Blue Team is scoffing at it, neither side with a ton to go on scientifically, is a new low for our nation.
The political nature of this drug because Trump said it is bizarre, but that is the media we have (and hate). I have said it many times - I hope both drugs/treatments work and hope they find even more. Any treatment with a good rate of effectiveness would be huge.
With that said, the doctors who have been using the HCQ treatment have convinced me that it is effective with little side effects. I don’t care what the media says. They have no incentive to lie about what they have been doing and no dog in the political fight - they are treating real people.
If I catch this and get sick I am demanding the HCQ treatment (with zinc sulfate and a Z-pak).
However, I would be happy if Remdesivir or another drug worked too. The more the merrier!
This drug far from bombed. It made a significant difference in both recovery time and death rate. It is not a cure but is a piece of the puzzle
did you read? 27% serious side effects in the placebo group
Amen
What's that?
Did you mean HCQ? Or is there an HCL (hydrochloric acid) treatment?
When you’ve lived through the HIV fiasco, this is nothing.
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