Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

Early Antibody Testing Indicates Far More COVID-19 Cases, Lower Mortality Rate
NBC News Los Angeles affiliate ^ | April 20, 2020

Posted on 04/20/2020 7:20:23 PM PDT by grundle

Although there is a decrease in the number of deaths, the study indicates that there could be hundreds of thousands of people who could be infected without knowing it.

Preliminary results from an antibody testing program indicates the number of COVID-19 infections in Los Angeles County far exceeds the number of confirmed cases, with potentially more than 400,000 residents having been infected at some point, USC researchers and county health officials announced Monday.

The good news from the antibody study, researchers said, is that the mortality rate from the illness is much lower than currently estimated. The bad news is that there are potentially hundreds of thousands of residents who are unknowingly infected with the illness and not showing any symptoms, but are still capable of spreading it to others.

The numbers prove that “we are very early in the epidemic,” said USC professor Neeraj Sood of the USC Price School for Public Policy.

County public health director Barbara Ferrer said the figures also show that with thousands of residents likely infected and capable to transmitting the virus, social-distancing requirements need to remain in place.

As of Monday, the number of COVID-19 cases confirmed by testing stood at 13,816 -- a fraction of the maximum estimate of 442,000 cases indicated by the antibody study. Researchers are testing for antibodies in adults over time in an effort to determine the scope and spread of the coronavirus pandemic across the county. The testing began in early April with a representative sample of 863 residents.

A rapid antibody test was used for the study, which was conducted at six drive-through test sites. The researchers plan to test new groups of participants every few weeks to gauge the pandemic's trajectory.

Based on the first round of testing, the research team estimated that roughly 4.1% of the county's adult population has developed antibodies to the virus -- an indication they are or were infected at some point. Adjusting for the statistical margin of error implies that approximately 221,000 to 442,000 adults in the county have had the infection.

That estimate is 28 to 55 times higher than the 7,994 confirmed cases of COVID-19 reported to the county by the time of the study in early April. “We haven't known the true extent of COVID-19 infections in our community because we have only tested people with symptoms, and the availability of tests has been limited,” Sood, the lead investigator on the study, said. “The estimates also suggest that we might have to recalibrate disease prediction models and rethink public health strategies.”

The results have important implications for public health efforts to control the local epidemic.

“These results indicate that many persons may have been unknowingly infected and at risk of transmitting the virus to others,” Ferrer said. “These findings underscore the importance of expanded polymerase chain reaction (PCR) testing to diagnose those with infection so they can be isolated and quarantined, while also maintaining the broad social distancing interventions.”

The antibody test is helpful for identifying past infection, but a PCR test is required to diagnose current infection.

More than 600 people have died of the virus countywide. “Though the results indicate a lower risk of death among those with infection than was previously thought, the number of COVID-related deaths each day continues to mount, highlighting the need for continued vigorous prevention and control efforts,” said Dr. Paul Simon, chief science officer at L.A.

County Department of Public Health, who co-led the study.

The study's results have not yet been peer reviewed by other scientists. The test's accuracy was assessed at a lab at Stanford University, using blood samples that were positive and negative for COVID-19.

The study was supported with funding from the USC Schwarzenegger Institute, USC Lusk Center, USC President's Office, Jedel Foundation, LRW Group, Soap Box Sample, and several individual donors.


TOPICS: Miscellaneous
KEYWORDS:
This is good news. Since the infection rate is that much higher, it means that the fatality rate is that much lower.
1 posted on 04/20/2020 7:20:23 PM PDT by grundle
[ Post Reply | Private Reply | View Replies]

To: grundle

There was a nasty one going around mid-Missouri in January. Worst I and everybody I know ever had. Took two months to clear out your lungs.

I’d bet dollars to doughnuts it was Cornavirus.


2 posted on 04/20/2020 7:22:54 PM PDT by E. Pluribus Unum ("The duty of a true patriot is to protect his country from its government." - Thomas Paine)
[ Post Reply | Private Reply | To 1 | View Replies]

To: grundle

Up to 442,000 people in L.A. County may have already had coronavirus, antibody study estimates
https://ktla.com/news/local-news/up-to-442000-people-in-l-a-county-may-have-already-had-coronavirus-antibody-study-estimates/

by: Nouran Salahieh, Jennifer McGraw
Posted: Apr 20, 2020 / 02:03 PM PDT / Updated: Apr 20, 2020 / 07:18 PM PDT


3 posted on 04/20/2020 7:39:17 PM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: E. Pluribus Unum

I’m in PA.

Mine hit lightening fast on January 13 and stayed in my left lung until around February 9.

Nasty $hit but not worth shutting down the nation.


4 posted on 04/20/2020 7:40:12 PM PDT by lightman (I am a binary Trinitarian. Deal with it!)
[ Post Reply | Private Reply | To 2 | View Replies]

To: grundle

What is the false positive rate for this test?


5 posted on 04/20/2020 7:49:45 PM PDT by TChad (The MSM, having nuked its own credibility, is now bombing the rubble.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: TChad

Bttt


6 posted on 04/20/2020 7:51:09 PM PDT by Guenevere (Press On!)
[ Post Reply | Private Reply | To 5 | View Replies]

To: grundle

They have been consistently saying at the press briefings there is no approved accurate covid antibody test available yet.


7 posted on 04/20/2020 7:57:35 PM PDT by dynoman (Objectivity is the essence of intelligence. - Marilyn vos Savant)
[ Post Reply | Private Reply | To 1 | View Replies]

To: TChad

Yeah, we don’t have an approved test yet. The accuracy of current tests is a problem, and why none have been approved. I wonder where they got the tests.


8 posted on 04/20/2020 7:59:09 PM PDT by dynoman (Objectivity is the essence of intelligence. - Marilyn vos Savant)
[ Post Reply | Private Reply | To 5 | View Replies]

To: E. Pluribus Unum

I heard someone in Springfield say that exact thing.
Went around his office and took weeks to get over.


9 posted on 04/20/2020 8:07:30 PM PDT by GnuThere
[ Post Reply | Private Reply | To 2 | View Replies]

To: GnuThere

We think my wife had it in mid February....took a month to get over...

I think it went thru Florida in February and March..maybe earlier

Orlando gets six million visitors a month...well they use to

The economy will never recover with CDC guidelines..

Testing will only scare people..

The depression is around the corner..

There are a million in the oil industry headed for the bread lines..


10 posted on 04/20/2020 8:20:40 PM PDT by Hojczyk
[ Post Reply | Private Reply | To 9 | View Replies]

To: grundle

“That estimate is 28 to 55 times higher”

Santa Clara county study by Stanford showed 50-85 times higher.

These same sort of results are coming in from from various places.


11 posted on 04/20/2020 8:40:53 PM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
[ Post Reply | Private Reply | To 1 | View Replies]

To: E. Pluribus Unum

My older son had similar back in January. 99% sure he had it too.


12 posted on 04/20/2020 8:45:06 PM PDT by JaguarXKE (Liberalism is a cancer on our nation.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: Hojczyk

Oh would you shut up chicken little


13 posted on 04/20/2020 11:11:27 PM PDT by Hoosier-Daddy ("Washington, DC. You will never find a more wretched hive of scum and villainy. We must be cautious")
[ Post Reply | Private Reply | To 10 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson