Posted on 03/22/2020 1:19:20 PM PDT by FarRockaway2
[Editor's note: Lack of FDA approval does not prohibit off-label use of drugs for other threapeutic purposes, but would inhibit widespred use.]
You are being lied to about the drugs that heal COVID19.
America's FDA, and National Institute of Allergy and Infectious Diseases Director Dr. Anthony Fauci, are dragging their feet on approving a drug that provides very strong positive effect on COVID19.
Fauci, speaking from the White House, said on the matter of approving Hydroxychloroquine and azithromycin:
(Excerpt) Read more at americanthinker.com ...
It takes Fauci to task for saying there needed to be, "a randomized clinical trial" then suggests he's wrong that there haven't been any by citing an article which clearly says, "Gautret et al. (2020) writing Hydroxychloroquine and azithromycin as a treatment of COVID‐19: results of an open‐label non‐randomized clinical trial.
It goes on like that acting like Fauci was saying there was no science done, which is not what he said at all. It's just dumb.
There is nothing quiet about it. Everyone is doing it.
an open label non randomized clinical trial does not meet the threshold for scientific evidence that one treatment is better than another and is therefore anecdotal. Notice i did not say no data or that the data that exists is not promising
OMG this is so STUPID!
Hydroxychloroquine is an approved drug.
No one has to "approve" it for use to treat COVID-19, its use for this purpose is standard everywhere in the United States. I prescribed it for this purpose yesterday.
Hydroxychloroquine is an approved drug, and it has been approved for many, many years.
No approval to use it for COVID-19 is required.
Yep, and Economy Schonomy.
Wikipedia: "Hydroxychloroquine was approved for medical use in the United States in 1955.[2] It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[6] The wholesale cost in the developing world is about US$4.65 per month"
Drugs only get approved once. This drug has been approved by the FDA FOR SIXTY FIVE YEARS.
I have been a Trump supporters since early on.
A few times, i will admit, i was baffled by how he approached something but every time it turned out he was right.
It’s been awhile since i have been baffled.
That is until now.
I am not sure why he is not pushing the Malaria drug???
Chloroquine poisoning being reported in Nigeria from "self-dosing".
My understanding of the Chloroquine and Hydroxychloroquine is that it interferes with the ability of the virus to replicate. When that happens the bodies own defenses can take care of the virus.
Since I KNOW that I don't have to worry about malaria I can cross that those of my list.
My father got malaria in North Africa when we was in the U.S. Army.
He was a strong, fit young man and he recovered. But malaria negatively affected his heart (which it usually does) and my father died at only 58...heart trouble.
I would bet if you did half the dose normally used for Malaria and just a zinc supplement like Cold-Eeze it would knock down the symptoms for the vast majority who are actually Corona Positive.
To some extent, the Doctors hoarding tells us this is like the Face Mask lie, intended to cut the rush to grab up these supplies which is mostly fine but shouldn’t have been done with a lie.
In the end, this is going to be the way to fight the flu in years to come.
Lemme splain.....
...........
“Despite its small sample size”
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That means 20 people were treated, that’s all folks, 20.
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When all of you gloom and doomers become doctors you will find out that treatment surveys of 20 patients are not very credible.
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They may be absolutely correct.
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Until the sample size is in the hundreds, better, in the thousands, and sampled from widely different areas and ages, and gender, the results are in fact important, but still anecdotal.
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Everybody needs to get off Fauci’s case. He is working at the edge of exhaustion with all his fellow professionals and they deserve out absolute respect.
Its not the only peer-reviewed science paper. Its just one of them.
Let me ask you, in your opinion, how many human beings will get hydroxychloroquine who are hospitalized for COVID19 if
a) its under present “compassionate use” “off lable”
or in the case
b) FDA approved specifically for COVID19
?
No. It does not.
It takes him to task for calling the evidence supporting hydroxychloroquine anecdotal.
It cites several peer reviewed journal articles including Nature, two official government guidelines, then says that is definitely not anecdotal.
And that is entirely true.
What is a reasonable estimate for the fastest possible double blind clinical study of hydroxychloroquine on COVID19 patients? Does anyone believe that will be done in a month?
Please recognize that such a study means giving half the patients...nothing that helps.
But the gaussian function tells us that in 1 month it is highly probable that we will have on the order of a million infected in the USA. Somewhere around 1 to 1.3 million, likely every hospital bed in the country will be full. And there will be no doctors available to see the next patient. Realistic numbers estimate many millions of infected Americans again looking simply at the realities of the exponential climb. That isn’t doom-saying - its math.
So while you wait for 4 weeks? 5? 10? for your double blind study, you are going to have one million plus infected, 200,000 in need of care, filled up hospitals, and 20,000 dead.
Please note that there are already multiple papers of measurements of the effectiveness of this drug, and thousands of papers defining the safety.
So you have a drug that is known-safe, known to have some anti-viral properties, is supported by multiple peer reviewed papers, and 20,000 people headed into the grave, and the response is “No. You should not give it except to a tiny number of people, and half of that number should receive a sugar pill, and we should wait weeks in this condition to see the results before we allow many people to have the drug.”
Sorry. That’s not saving lives. That’s worshipping rules in a time of crisis where the rules are not sufficiently helping at life saving.
the reason you put so much effort into double-blind is that in peacetime when you want to get the maximum amount of information and optimize the best dosing and eliminate noise in the data, you have this luxury. But this is Pearl harbor. we are being bombed out of existence. You have act and react on the schedule of the exponential function - not on the schedule of some fastidious ideal that only has application when you don’t have a nuclear bomb going off in your living room.
for. COVID19.
Again: how many doses are going to happen if its FDA approved FOR COVID19, and how many will happen if it remains on the compassionate use only classification?
New York State also.
Your immune system kills them. However your immune system needs time. Your body has to randomly produce antibodies in response to the virus. Once one antibody is able to attach to a virus immune cells can then destroy the virus and the antibody that attaches is now ramped up by the immune system. If your immune system can do that faster than the virus can cause damage you have a mild course. If not you can die.
The 2 medications mentioned seem to interfere with various parts of the virus lifecycle and/or our inflammatory response that leads down the path to ARDS(acute respiratory distress syndrome). With diminished replication and your inflammatory response under control your immune system has time to destroy and clear the virus from your system.
There is a nice review of the immune system cira 2000 in the NEJM.
The Immune System - Part 1
The Immune System - Part 2
Sorry that it requires a subscription.
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