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THis story doesn't make sense to me.
1 posted on 06/05/2019 10:33:08 AM PDT by RummyChick
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To: RummyChick

Yes
Why would a drug company hide a poten market


2 posted on 06/05/2019 10:35:36 AM PDT by Rocko Jack
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To: RummyChick

Agreed - they would have another Viagra (which was originally for heart conditions) on their hands if this is true. I suspect that they might be investigating this but it’s under the correlation is not causation category.


3 posted on 06/05/2019 10:37:05 AM PDT by JMS
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To: RummyChick
"THis story doesn't make sense to me."

Exactly. There's more going on here.

If they could get the drug labeled for use in treating Alzheimer's (in addition to RA), their sales would increase. Why would a drug company hold back on that is that was the only issue in play?

4 posted on 06/05/2019 10:37:31 AM PDT by rxsid (HOW CAN A NATURAL BORN CITIZEN'S STATUS BE "GOVERNED" BY GREAT BRITAIN? - Leo Donofrio (2009))
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To: RummyChick

I think I agree with Pfizer here.

Any company would jump at a chance to make billions off of a working Alzheimer’s drug.

There’ve been several widely publicized drugs that hit the market for testing that promptly failed (and hurt the company financially in the process) that Pfizer taking a conservative approach may have been prudent.


7 posted on 06/05/2019 10:38:34 AM PDT by Skywise
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To: RummyChick

Note the date...

!UW.yye1fxo
>>> 7 Feb 2018 - 10:06:12 PM <<<
What if cures already exist?
What about the billions (public/private/govt) provided to fund cure dev?


9 posted on 06/05/2019 10:39:45 AM PDT by Cletus.D.Yokel (No dolphins were harmed in the making of this post. They enjoyed the rough handling.)
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To: RummyChick

It is very simple.

If they would have said anything, the FDA would have forbidden them to make such claims.


10 posted on 06/05/2019 10:40:01 AM PDT by Innovative
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To: RummyChick

Remember, the media love salacious headlines - EVIL DRUG COMPANY DOES XXX

The US FDA would come down on Pfizer ike a ton of bricks if they claimed their drug treated an “unrelated” disease. Liability potential would be outrageous also. They certainly would NOT be allowed to market the drug for Alzheimers unless years of studies were conducted.


12 posted on 06/05/2019 10:40:47 AM PDT by PGR88
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To: RummyChick

Probably just an indicator that they are working with the government to contaminate the water supply with inflammatories thereby causing Alzheimer’s in selected populations. Apparently dumbing down the education system is not doing enough for the central planners’ taste.


14 posted on 06/05/2019 10:42:34 AM PDT by fruser1
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To: RummyChick

More likely there was some indication but test trials would have been so expensive they wouldn’t recover the cost.
At Intel, we abandoned many designs as analysis said little return on investment.

We had several designs in the works which were trending so badly, we just said “no more”


16 posted on 06/05/2019 10:43:22 AM PDT by Zathras
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To: RummyChick
Even if the patent was going to run out on Embrel itself, the trials could have resulted in a slightly modified, re-purposed drug for which a new patent would apply.

Doing absolutely nothing until the patent for Embrel ran out means they've given up whatever advantage they would have had to develop a new drug first.

Doesn't make sense.

17 posted on 06/05/2019 10:43:32 AM PDT by Bruce Campbells Chin
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To: RummyChick
They don't dare make such a claim without good data.

19 posted on 06/05/2019 10:46:21 AM PDT by BitWielder1 (I'd rather have Unequal Wealth than Equal Poverty.)
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To: RummyChick

Well, if the formulation is the PEDIATRIC vial package shown, I can think of one reason why patients who take PEDIATRIC Embrel might be 65% less likely to get alzheimer’s than the general population... ;-)


22 posted on 06/05/2019 10:49:54 AM PDT by dangus
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To: RummyChick

I know pharmas are about $$$$$$$.

I’ve also read of cases, as with Lyme’s Disease, where medical/insurance boards block effective treatments with available regimens (long-term doxy), because a vaccine is on the way (providing $$$$$ pharma income),


23 posted on 06/05/2019 10:51:04 AM PDT by polymuser (It's discouraging to think how many people are shocked by honesty and how few by deceit. Noel Coward)
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To: RummyChick
"One of the world's biggest drug firms deliberately buried data showing one of its arthritis medications could slash the risk of Alzheimer's."

What does "buried the data" mean? Does the fact they chose not to publicize certain data mean they "buried" it? They could easily have made the business decision that the data wasn't solid enough to justify spending millions and millions to research the drug for this new purpose. Especially if there are already other, more promising, drugs for this undergoing clinical trials.

27 posted on 06/05/2019 10:53:22 AM PDT by circlecity
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To: RummyChick
THis story doesn't make sense to me.

Makes sense to me. A couple of ways.

First off, people would be asking to get the medication to help prevent Alzheimer's and perhaps doctors would be tempted to prescribe it for that purpose. It wasn't developed for that purpose.

Secondly, Pfizer might have planned (just my guess) to develop a version of the drug for Alzheimer's and other purposes. That way, they would have TWO drugs in the market, making perhaps twice as much or more.

Thirdly, it they had acknowledged the secondary benefits from Embrel, who's to say that other drug makers might not have jumped at the opportunity and beaten Pfizer to market with the anti-Alzheimer's medicine?

Just my guesses, and I'm pretty sure the shareholders would have gotten on Pfizer's case if they had allowed other drug makers to beat them to market with such a product.
28 posted on 06/05/2019 10:55:35 AM PDT by adorno
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To: RummyChick

Just taking a wild guess here:

They feared that if word got out off-label use of their drug for this purpose would skyrocket. Then later, if some horrible risk was discovered, they’d be on the hook for untold billions in liabilities.


30 posted on 06/05/2019 10:57:22 AM PDT by Buckeye McFrog (Patrick Henry would have been an anti-vaxxer.)
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To: RummyChick
If I had to guess I'd say it had something to do with the labyrinthian regulations regarding drug production and marketing, and the real probability of lawsuits costing billions of dollars if something being used in an ad hoc manner didn't work or caused some real harm.

Cancer would probably be cured by now, if we didn't have an FDA.

33 posted on 06/05/2019 10:59:35 AM PDT by Mr Ramsbotham ("God is a spirit, and man His means of walking on the earth.")
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To: RummyChick

Actually what they found is that people who remembered to take their Enbrel daily were 64% less likely to have alzheimer’s

;)


50 posted on 06/05/2019 11:19:23 AM PDT by edwinland
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To: RummyChick
This analysis is based on what is called "happenstance data".

If the two groups (Alzheimer's and non-Alzheimers) were not controlled for all other variables (for instance, age) then the results are meaningless.

This is the problem called "hidden variables" or "confounding factors".

52 posted on 06/05/2019 11:21:16 AM PDT by sima_yi ( Reporting live from the far North)
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To: RummyChick

Evidence the drug might work was found in 2015. Patent was going to run out in 2018. Thanks to big government, the cost would be too great in time and money to do clinical trials.The low ratio of benefits to costs to the company would have made the decision to do the trials irrational.


56 posted on 06/05/2019 11:25:36 AM PDT by mjp ((pro-{God, reality, reason, egoism, individualism, natural rights, limited government, capitalism}))
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