Posted on 04/17/2019 11:43:36 AM PDT by LibWhacker
Yale scientists say experiment opens new frontier in brain research 35 minutes ago Re-vitalised brains of dead pigs said to be ‘cellularly active’. Photograph: Damien Meyer/AFP/Getty
Re-vitalised brains of dead pigs said to be ‘cellularly active’. Photograph: Damien Meyer/AFP/Getty
An experiment has breathed life into the brains of pigs four hours after death. Scientists in the US restored circulation and cellular activity in 32 pig brains obtained from a meat-packing plant.
While there was no evidence of re-awakening awareness or consciousness, the re-vitalised brains were said to be “cellularly active”.
The study has implications that challenge long-held assumptions about the finality of death, and opens up a new frontier in brain research.
Lead scientist Prof Nenad Sestan, from Yale University, said: “The intact brain of a large mammal retains a previously under-appreciated capacity for restoration of circulation and certain molecular and cellular activities multiple hours after circulatory arrest.”
Cellular brain death is usually considered to be swift and irreversible.
Once the supply of oxygen and blood are cut off, the brain’s electrical activity and signs of awareness vanish within seconds.
A cascade of destruction then occurs leading to widespread degeneration from which there is no turning back.
However, Prof Sestan and his team noticed that small brain tissue samples routinely showed signs of cellular life returning, even when harvested hours after death.
To investigate further, they turned their attention to whole, intact brains from pigs processed for food production.
Chemical blood
In a ground-breaking experiment, a specially designed “chemical blood” preservative was circulated through the brains of dead animals that had been slaughtered four hours earlier.
The solution, warmed to normal body temperature, was perfused through the brains’ blood vessels for six hours.
During this time the scientists observed a reduction in cell death and the restored functionality of certain nerve, blood vessel and glial cells.
Glial cells are important brain “support cells” that hold neurons in place, feed them with nutrients and oxygen, provide insulation, and clean up the carcasses of dead cells.
The revived activity even included some synaptic function, the transmission of signals between neurons.
Details of the study are published in the latest issue of Nature journal.
Co-author Dr Zvonimir Vrselja, also from Yale, said: “At no point did we observe the kind of organised electrical activity associated with perception, awareness, or consciousness.
“Clinically defined, this is not a living brain, but it is a cellularly active brain.”
Lessons learned from the study could in future help doctors find ways to salvage brain function in stroke patients, or test the effectiveness of treatments designed to aid cellular recovery after injury, say the scientists.
The “BrainEx” system developed at Yale could also provide a powerful research tool.
Andrea Beckel-Mitchener, from the US National Institute of of Mental Health, which co-funded the research, said: “This line of research holds hope for advancing understanding and treatment of brain disorders and could lead to a whole new way of studying the post-mortem human brain.”
Any future studies involving human tissue or the possible revival of global electrical activity in “dead” animal brains would have to undergo strict ethical supervision, the team stressed.
However, it was unclear that the technique would work in a recently deceased human brain.
The chemical solution lacked many components found naturally in human blood, such as immune system cells.
Dr Stephen Latham, director of Yale University’s Interdisciplinary Center for Bioethics, said: “Restoration of consciousness was never a goal of this research.
“The researchers were prepared to intervene with the use of anaesthetics and temperature-reduction to stop organised global electrical activity if it were to emerge.
“Everyone agreed in advance that experiments involving revived global activity couldn’t go forward without clear ethical standards and institutional oversight mechanisms.”– PA
It’s the reincarnation of Jihadists..
Frankenswine!
Ezekiel and the dry bones.
There it is...
:D
(By the way, has anyone heard if AOC has expressed any opinions about swinish flatulence yet?)
“What if brain death was like wiping a hard drive ...”
Like wiping it with a cloth?
But will it work on snowflakes?
I’ve seen this movie...
Does that reference refer to the rebirth of Israel, or physical death? The molecules of most of the dead in that valley have long ago been dispersed.
Be VERY afraid.
Me either - but my body is...
Years later he is revived but no longer has a soul. And without a soul, he becomes a relentless killer......
:)
Yeah, I was only kidding. I’m starting to lean in the direction that, to use an analogy, our entire body, including the brain, is what we call, in IT, a “think client”. Our personality and our personhood is really “in the cloud”, but temporarily resides in RAM, also called the brain, kinda like a cloud based app. So all that is really happening in thees experiments is they are firing up a bad computer and getting the little rectangle on the screen to flash. There is nothing in memory and the computer is not really functioning.
***Re-vitalised brains of dead pigs said to be ‘cellularly active’.***
Nothing new. My ancestors, going way back refused to vote as it would put them on Jury duty lists.
Since their deaths, they have never missed an election always rising from the dead and voting Democrat.
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