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Stem cell transplant 'game changer' for MS patients
BBC ^ | March 18, 2018 | Fergus Walsh

Posted on 03/19/2018 8:28:16 AM PDT by Seizethecarp

Doctors say a stem cell transplant could be a "game changer" for many patients with multiple sclerosis. Results from an international trial show that it was able to stop the disease and improve symptoms. It involves wiping out a patient's immune system using cancer drugs and then rebooting it with a stem cell transplant. Just over 100 patients took part in the trial, in hospitals in Chicago, Sheffield, Uppsala in Sweden and Sao Paulo in Brazil. They all had relapsing remitting MS - where attacks or relapses are followed by periods of remission. The patients received either haematopoietic stem cell transplantation (HSCT) or drug treatment. After one year, only one relapse occurred among the stem cell group compared with 39 in the drug group. After an average follow-up of three years, the transplants had failed in three out of 52 patients (6%), compared with 30 of 50 (60%) in the control group. Those in the transplant group experienced a reduction in disability, whereas symptoms worsened in the drug group. Prof Richard Burt, lead investigator, Northwestern University Chicago, told me: "The data is stunningly in favour of transplant against the best available drugs - the neurological community has been sceptical about this treatment, but these results will change that." The transplant costs around £30,000, about the same as the annual price of some MS drugs. Doctors stress it is not suitable for all MS patients and the process can be gruelling, involving chemotherapy and a few weeks in isolation in hospital. Dr Susan Kohlhaas, director of research at the MS Society, said the stem cell transplant HSCT "will soon be recognised as an established treatment in England - and when that happens our priority will be making sure those who could benefit can actually get it".

(Excerpt) Read more at bbc.com ...


TOPICS: Culture/Society; United Kingdom
KEYWORDS: ms; multiplesclerosis; primaryprogressive; stemcell
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This looks like the real deal, not tabloid dreams, folks!
1 posted on 03/19/2018 8:28:17 AM PDT by Seizethecarp
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To: Seizethecarp

I’m guessing adult stem cells (as the early trials with fetal stem cells produced horrifying results).


2 posted on 03/19/2018 8:31:48 AM PDT by Buckeye McFrog
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To: Buckeye McFrog

An article highlighting actual health benefits has got to be about Adult Stem Cells.
The work done with Embryonic Stem Cells never results in anything good.


3 posted on 03/19/2018 8:33:34 AM PDT by ClearCase_guy (Racism against Whites is a real thing. Let's stop pretending it isn't.)
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To: Seizethecarp

As someone with a close friend suffering from MS, I sure hope they fast track this. Every annual visit to check progression is a nerve-wracking experience for all involved.


4 posted on 03/19/2018 8:35:18 AM PDT by ConservativeWarrior (Fall down 7 times, stand up 8. - Japanese proverb)
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To: Seizethecarp

My mom had something similar done. She’s had the relapsing form for 20+ years.

After the other medicines stopped working, she went to the chemo drugs.

She’s completely in remission now.

It’s amazing. We didn’t think she’d still be around...and she has no symptoms.

:))))

It’s no dream, it’s true A.F.


5 posted on 03/19/2018 8:36:00 AM PDT by 1_Inch_Group (Country Before Party)
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To: Buckeye McFrog

Yes, I think the ghouls who were trying to sell fetal stem cells as some sort of wonder cure have been proven wrong, and adult stem cells are turning out to be far more useful/effective...


6 posted on 03/19/2018 8:36:18 AM PDT by Sicon ("All animals are equal, but some animals are more equal than others." - G. Orwell)
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To: Seizethecarp

First, you have to have the “right” kind of MS, RRMS, relapsing remitting MS for this treatment to apply. There are three other kinds, the last time I looked, which may actually really be different diseases having different underlying mechanisms and would not respond to this “cure”.

A decade ago I was screened for PPMS, primary progressive MS, a late-onset MS that tends to hit older males and is slow moving. It is often diagnosed “only on autopsy.” I have been taking 40 mg of baclofen daily for 10 years to preserve my ability to move without “spasticity,” a symptom that all MS sufferers are familiar with.

https://www.nationalmssociety.org/Symptoms-Diagnosis/MS-Symptoms/Spasticity


7 posted on 03/19/2018 8:40:07 AM PDT by Seizethecarp
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To: Seizethecarp

The patients received either haematopoietic stem cell transplantation (HSCT) or drug treatment.

...

Not that long ago the Democrats and their crooked media told us the only way to get these cures was to kill babies.

Thanks for the article. The results look promising.


8 posted on 03/19/2018 8:40:46 AM PDT by Moonman62 (Make America Great Again!)
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To: Seizethecarp

First, you have to have the “right” kind of MS, RRMS, relapsing remitting MS for this treatment to apply.

...

In general or only for this study?


9 posted on 03/19/2018 8:41:45 AM PDT by Moonman62 (Make America Great Again!)
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To: Buckeye McFrog

Here is the key line from the article for those concerned about the stem cell issue:

“Stem cells taken from the patient’s blood and bone marrow are then re-infused.”

The patient’s OWN stem cells are used!


10 posted on 03/19/2018 8:43:16 AM PDT by Seizethecarp
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To: Seizethecarp

YEP!


11 posted on 03/19/2018 8:45:13 AM PDT by 1_Inch_Group (Country Before Party)
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To: Sicon

The ghouls need baby stem cells for their Ba’al research.

/sarc


12 posted on 03/19/2018 8:49:32 AM PDT by fishtank (The denial of original sin is the root of liberalism.)
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To: Seizethecarp

Hyperbaric oxygen therapy has been shown in clinical trials to be of significant benefit. Of course that has been suppressed as is detailed in the excellent book: “OXYGEN and the BRAIN”.


13 posted on 03/19/2018 8:49:51 AM PDT by Captain7seas (UNexit. Make America Great Again!)
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To: ConservativeWarrior

See POST 13


14 posted on 03/19/2018 8:50:45 AM PDT by Captain7seas (UNexit. Make America Great Again!)
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To: Captain7seas

Thanks. I’ll ask if she’s considered that.

Truly a shame, her MS. Easily the kindest and most thoughtful person I’ve ever met.


15 posted on 03/19/2018 8:53:00 AM PDT by ConservativeWarrior (Fall down 7 times, stand up 8. - Japanese proverb)
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To: Buckeye McFrog

They never really say if it’s adult or embyronic anymore. One can interpret that one of two ways: Either it’s now so obvious that embryonic stem cells are uselss that it goes without saying that they are referring to adult stem cells OR they want to keep alive the impression that embryonic stem cells are great so they avoid saying “adult stem cells”. You decide.


16 posted on 03/19/2018 8:55:01 AM PDT by pepsi_junkie (Russians couldnt have done a better job destroying sacred American institutions than Democrats have)
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To: Seizethecarp

I’ve read about this experimental treatment before. What most article don’t mention is that the protocol is not suitable for everyone with MS. For some the severity of the side effects make it not feasible.

https://www.sciencedaily.com/releases/2016/06/160609222439.htm

My late neurologist was involved in the research and development studies of a drug for the primary progressive form of MS. It was approved for trials by FDA shortly before he died.


17 posted on 03/19/2018 9:08:05 AM PDT by lastchance (Credo.)
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To: pepsi_junkie

Everyone who knows that tee tiny embryo is another PERSON knows that that they set up rejection mechanisms and worse.


18 posted on 03/19/2018 9:10:08 AM PDT by amihow
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To: Seizethecarp

“will soon be recognised as an established treatment in England - and when that happens our priority will be making sure those who could benefit can actually get it”.

If they can survive long enough on the NHS wait lists.


19 posted on 03/19/2018 9:28:53 AM PDT by VanShuyten ("...that all the donkeys were dead. I know nothing as to the fate of the less valuable animals.")
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To: Seizethecarp

good news


20 posted on 03/19/2018 9:39:30 AM PDT by plain talk
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