yes, regularly with a long barreled high standard 12 ga full choked magnum
I, personally, would not attempt a duck beyond 60-70 yards, for ethical reasons, but I would not hesitate for a drone.
I have no desire to shoot airplanes out of the sky, nor will I shoot at a drone that is up around 400 feet or so.
(Well, I may shoot at it, but I have no great hopes of hitting it, and if I do hit it, it would be luck.)
I'm not being obtuse, but I believe in absolute property rights and see no reason why I should allow a flying camera to hover over me and watch what I'm doing.
Period.
I will shoot, shovel and shut up.