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New Weapon in Fight Against 'Superbugs'
WSJ ^ | June 30, 2014 8:47 p.m. ET | By Ann Lukits

Posted on 07/02/2014 9:48:19 AM PDT by Red Badger

Some harmful bacteria are increasingly resistant to treatment with antibiotics. A discovery might be able to help the antibiotics treat the disease.

A soil sample from a national park in eastern Canada has produced a compound that appears to reverse antibiotic resistance in dangerous bacteria.

Scientists at McMaster University in Ontario discovered that the compound almost instantly turned off a gene in several harmful bacteria that makes them highly resistant to treatment with a class of antibiotics used to fight so-called superbug infections. The compound, called aspergillomarasmine A, or AMA, was extracted from a common fungus found in soil and mold.

Antibiotic resistance is a growing public-health threat. Common germs such as Escherichia coli, or E. coli, are becoming harder to treat because they increasingly don't respond to antibiotics. Some two million people in the U.S. are infected each year by antibiotic-resistant bacteria and 23,000 die as a result, according to the Centers for Disease Control and Prevention. The World Health Organization has called antibiotic resistance a threat to global public health.

The Canadian team was able to disarm a gene—New Delhi Metallo-beta-Lactamase-1, or NDM-1—that has become "public enemy No. 1" since its discovery in 2009, says Gerard Wright, director of McMaster's Michael G. DeGroote Institute for Infectious Disease Research and lead researcher on the study. The report appears on the cover of this week's issue of the journal Nature.

(Excerpt) Read more at online.wsj.com ...


TOPICS: Business/Economy; Canada; Culture/Society; Government
KEYWORDS: antibiotic; disease; fungus; medicine; resistant; superbug

Some harmful bacteria are increasingly resistant to treatment with antibiotics. This common fungus found in soil might be able to help the antibiotics combat diseases. Corbis

1 posted on 07/02/2014 9:48:19 AM PDT by Red Badger
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To: Red Badger
Amazing! Science rocks.
2 posted on 07/02/2014 9:50:07 AM PDT by ConservingFreedom (A goverrnment strong enough to impose your standards is strong enough to ban them.)
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To: Red Badger

This is good news. You can also use colloidal silver and oil of oregano. Both strong antibiotics. They also don’t have a problem with resisitance building up.


3 posted on 07/02/2014 9:55:09 AM PDT by Georgia Girl 2 (The only purpose o f a pistol is to fight your way back to the rifle you should never have dropped.)
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To: Red Badger

Must be an aspergillus fungus. I remember growing aspergillus in microbiology in high school.

And probably in my gym locker too ...


4 posted on 07/02/2014 9:57:51 AM PDT by IronJack
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To: Georgia Girl 2

Colloidal Silver?....Okay as long as you like the color blue...............


5 posted on 07/02/2014 9:58:14 AM PDT by Red Badger (I've posted a total of 2,752 threads and 85,005 replies. ..)
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To: Red Badger
re: New Weapon in Fight Against ‘Superbugs’

Damn! I have to start reading more careful. I read SuperBAGS instead of ‘Superbugs’. Then proceeded to read the article thinking I was going to see a way to rid us of Hillary Clinton or maybe Michelle Obama. What a disappointment. Just damn.

6 posted on 07/02/2014 10:00:04 AM PDT by Tupelo
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To: Red Badger

Well I didn’t say drink a gallon of it. LOL!!!


7 posted on 07/02/2014 10:00:16 AM PDT by Georgia Girl 2 (The only purpose o f a pistol is to fight your way back to the rifle you should never have dropped.)
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To: Georgia Girl 2

I could play Papa Smurf for Halloween for the rest of my life..............

8 posted on 07/02/2014 10:01:17 AM PDT by Red Badger (I've posted a total of 2,752 threads and 85,005 replies. ..)
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To: Red Badger

I knew that pic was coming. LOL!!!!


9 posted on 07/02/2014 10:05:21 AM PDT by Georgia Girl 2 (The only purpose o f a pistol is to fight your way back to the rifle you should never have dropped.)
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To: Red Badger

“Colloidal Silver?....Okay as long as you like the color blue...............”

That’s a greatly exaggerated concern when you examine the quality and quantity of the “colloidal silver” consumed in the rare cases where argyria has occurred.


10 posted on 07/02/2014 10:06:53 AM PDT by Magic Fingers (Political correctness mutates in order to remain virulent.)
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To: Red Badger
Does this mean obamamania has been eradicated?
11 posted on 07/02/2014 10:09:03 AM PDT by no-to-illegals (Scrutinize our government and Secure the Blessing of Freedom and Justice)
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To: no-to-illegals

Well, no, but it is in remission..................


12 posted on 07/02/2014 10:10:03 AM PDT by Red Badger (I've posted a total of 2,752 threads and 85,005 replies. ..)
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To: Red Badger

What about that evil woman? ... mooch ... Prayers said for its eradication too.


13 posted on 07/02/2014 10:11:52 AM PDT by no-to-illegals (Scrutinize our government and Secure the Blessing of Freedom and Justice)
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