In the thread about casting suggestions for a movie about the Boston Marathon Bombers, I added Clancy Brown (who is often cast as villains or authority figures) to play Janet Napolitano. He's a dead ringer for her and could nail it.
Clancy Brown as Homeland Security Director Janet "I know nothing" Napolitano
Great idea, we can have all butch lesbians played by men in drag.
Actually, I think Clancy Brown would have to butch up a little bit to play Janet.