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Posted on 02/03/2012 4:51:44 PM PST by TennesseeGirl
Clarksburg, MD—Two different research groups have independently made the same important discoveries on how Alzheimer’s disease spreads in the brain, according to a February 2 New York Times story. The groups’ findings have the potential to give us a much more sophisticated understanding of what goes wrong in Alzheimer’s disease and, more importantly, what can be done to prevent or repair damage in the brain.
The Times reported on the research teams of Bradley T. Hyman, MD, Ph.D., at Massachusetts General Hospital in Boston, and Karen E. Duff, Ph.D., of Columbia University Medical Center in New York.
Each research group found that the Alzheimer’s disease protein called tau can apparently spread from one part of the brain to other connected areas by effectively “jumping” from one nerve cell (neuron) to another. This is good news for scientists exploring pathways for treating Alzheimer’s disease, which is now a growing epidemic with the aging of the Baby Boomer generation and the sixth leading cause of death in the U.S. If scientists can determine how tau jumps from neuron to neuron, Alzheimer’s disease can potentially be stopped from spreading. (excerpted) http://www.ahaf.org/aboutahaf/press-room/media/two-new-alzheimers-studies.html
(Excerpt) Read more at ahaf.org ...
Thanks for posting this.
It’d be amazing if this could be prevented.
If scientists can determine how tau jumps from neuron to neuron
I’m not close to being a scientist, but it seems like it would be pretty hard to determine HOW it happens, seem like it would be hard then finding out THAT it happens.
Good work, hope they can find something that helps.
Yet another sad example of targeting symptoms without any clues about the underlying causation. Iron loading in the brain is what kills the neurons in Alzheimer’s. It appears first it the most metabolically active area: hippo campus.
As the hippo campus becomes more and more iron loaded the efficiency of the insulin signaling is eroded and the iron
becomes more loadable in less metabolically active areas of the brain where the insulin signaling is more robust. Iron
loading is an insulin mediated event.
“Iron loading in the brain is what kills the neurons in Alzheimer’s.”
Aluminum used to be the culprit, based on a withdrawn research paper.
What causes iron loading?
Humans are equatorially evolved: we ate mostly meat with plenty of iron and sweated 24/7. 12 hours of quality sweat has the iron loss equivalent of a pint of blood. Since we aren’t sweating out the iron we are obviously retaining it.
The modern lifestyle offers further exacerbations: since 1940 the fda has mandated that all of our baked goods be supplemented with pharmaceutical iron. Since 1969 all formula milk for babies has 30 times as much iron as breast milk.
Humans are equatorially evolved: we ate mostly meat with plenty of iron and sweated 24/7. 12 hours of quality sweat has the iron loss equivalent of a pint of blood. Since we aren’t sweating out the iron we are obviously retaining it.
The modern lifestyle offers further exacerbations: since 1940 the fda has mandated that all of our baked goods be supplemented with pharmaceutical iron. Since 1969 all formula milk for babies has 30 times as much iron as breast milk.
Interesting. What forms of iron cross the blood-brain barrier? What does insulin have to do with it?
A great number of human beings are designed to shed surplus iron load. This arose in the Arctic and Subarctic regions which are quite dusty with iron particles, and every animal you eat is carrying a near toxic load of the stuff.
What about iron in well water?
Some new research out showing lyme disease bacteria causing Alzheimers.......
http://www.jneuroinflammation.com/content/8/1/90/abstract
I read coconut oil helps
Iron is going to be a real doozy, considering oxidation of iron is our preferred method for transporting oxygen, as hemoglobin.
Coconut Oil apparently does have very interesting mitigating effect on a variety of functions of the nervous system.
I wonder if it has anything to do with a capacity for crossing the blood-brain barrier... That last is traced to fat solubility, if I remember correctly.
from what I read, there are components in coconut oil only found in breast milk. I t is supposed to help reverse alzheimers. The article was from a MD who provided the coconut oil for a few months to her husband who was diagnosed with Alzheimers. He is apparently now back to an active lifestyle making speeches.
http://alzheimersweekly.com/content/coconut-oil-alzheimers
Magnesium helps prevent the absorption of iron. Magnesium L-Threonate has been found by researchers at MIT to cross the blood-brain barrier and to improve mental function. It is available for purchase at Swanson’s Vitamins and others.
Yes. I’ve heard about the lyme disease link (theory). It’s intriguing. Also, there’s the school of thought that some alzheimer’s patients have a variant of neurosyphillis. Possibly mutated. Possibly dormant. What I find really puzzling is the number of alzheimer’s researchers who succumb to the disease themselves which leads me to suspect the viral/bacterial component is accurate. http://www.alzheimer-europe.org/Dementia/Other-forms-of-dementia/Infectious-Diseases/Syphilis
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