[MarMema]

Wow. I am so glad to be on your ping list.

[neverdem]

Super-sticky 'ultra-bad' cholesterol revealed in people at high risk of heart disease

Intestinal cell defense mechanism against bacteria

Terrorist 'pre-crime' detector field tested in United States

The Washington Diet - Following the government’s nutritional advice can make you fat and sick.

FReepmail me if you want on or off my health and science ping list.

[GloriaJane]

My body doesn’t like Ibuprofen. I have two crazy symptoms when ever I try to take it. One, I feel my temperament change. About an hour after taking an Ibuprofen I become angry, agitated, and feel like I could beat my way out of a wet paper bag. I snap at anyone who even looks my way. And that’s not like me!

But I feel it. I feel it coming on. I feel myself changing from my normal ho hum temperament into a crazy screaming she witch from h e double L.

The second symptom is that the next day my bladder makes me go a tiny bit a thousand times a day and my urethra hurts really really bad when I urinate. And there is blood in my urine if I take Ibuprofen for more then one day.

[concentric circles]

Thanks for posting the entire article. So many people seem to automatically hit the excerpt button without checking the "Excerpt Only" list.

[madison10]

Told my DH and he said: Sure it helps prostate issues, but it’ll put a hole in your stomach.” :o

[Salvation]

Hmmmm

[WVNan]

Problem is....the stuff will eat your stomach up. Nearly killed me when I took it for pain. My stomach has never really recovered.

[Myrddin]

Good thing I paid attention in O-chem and biochem classes. The article makes good sense. I put down 800 mg of ibuprofen daily. It keeps the rheumatoid arthritis in my spine at bay and reduces inflammation in my shoulder joints so I can maintain full mobility. Presumably, all the good work it is doing is fully "consuming" the dose. I always eat a ZoneBar with the dose so my stomach isn't empty. Additional benefits in suppressing prostate cancer is a definite plus.

[Myrddin]

The cycle was repeated, so that you end up with a net conversion of R to S. Lloyd explains that the significance of the finding is that while AMACR is doing the chiral conversion of ibuprofen, it is not able to promote cancer growth. In addition, the net conversion of R-ibuprofen to the active S-ibuprofen means that all of the drug can be used for its inflammatory effect.

This may lower the cost of ibuprofen as well. You don't have to be concerned about packaging purified S-ibuprofen. The racemized mix of R and S versions has a beneficial effect when the R version is being converted to the S version. You still get all the inflammation relieving value of the S version. Folks who want the cancer restraining version as purified R-ibuprofen can pay a little extra for that step. There is no justification for purifying the S-ibuprofen version now.