this is good news... and i needed a little god news this morning. pre-vascular is the key.
Posted on 10/29/2007 7:34:10 AM PDT by syriacus
Cold Spring Harbor Laboratory (CSHL) researchers led by Daniel Nolan and Assistant Professor Vivek Mittal have found that bone marrow (BM) derived endothelial progenitor cells (EPCs) play a critical role in the early stages of tumor progression and that eliminating EPCs stops cancer growth.
Using sophisticated high-resolution microscopy and flow cytometry, they zeroed in on the earliest stages of cancer progression and identified the role of EPCs in generating blood vessels that allow cancers to grow. "If we selectively blocked the EPCs, tumors were unable to make blood vessels and could not sustain their own growth," said Vivek Mittal, CSHL Assistant Professor.
(Excerpt) Read more at sciencedaily.com ...
"The new results show that EPCs are only present in the earliest stages of tumor progression, before the formation of blood vessels. "We found that the role of EPCs is to direct the formation and organization of the vascular structure that ultimately feeds the tumor as it grows," said CSHL researcher Daniel Nolan."
this is good news... and i needed a little god news this morning. pre-vascular is the key.
I hope you get more good news today!
thx...
There is also a link to a full text version. (which seems to be working and which has images).
Other interesting applications of the flow cytometer include Operation Desert Storm where small portable flow cytometers were mounted on HUMVEE's and sent out before advancing ground troops to scour the air for the biological warfare agent anthrax.
Would you agree that the primary use for this discovery is in the area of regrowth following treatment? It’s seems the percentage of pre-vascular tumors found at initial diagnosis wouldn’t be very high.
knowing next to nothing about it, i agree with you. but i am also hoping it will help them find the first/new ones someday, cause when it gets into the the blood/attachments to the vascular system it spreads where ever. if they could spot the markers before then it would be wonderful.
bmflr
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