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Early Ovarian Surgery Linked to Dementia
Washington Post (AP) ^ | August 29, 2007 | MALCOLM RITTER

Posted on 08/29/2007 10:43:34 PM PDT by dayglored

Early Ovarian Surgery Linked to Dementia

Women who have their ovaries removed before menopause run a heightened risk of developing dementia or other mental problems later in life _ unless they take estrogen until age 50, a new study suggests.

Experts said the research needs to be confirmed by further study, but the findings suggest another issue for premenopausal women and their doctors to discuss as they consider ovary removal....

Hormone therapy has been linked to a greater risk of dementia and heart attacks when given to women after age 65. But recent research indicates that when given before menopause or just afterward, it doesn't raise heart attack risk and may protect against dementia....

Ovaries produce estrogen. Rocca said the likeliest explanation of the study results is that removing ovaries causes a sudden deficiency of that hormone, which in turn affects the brain....

(Excerpt) Read more at washingtonpost.com ...


TOPICS: Culture/Society
KEYWORDS: dementia; estrogen; ovaries; surgery
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I'm going to forego the too-easy jokes about estrogen and dementia, because this really is a serious health and quality-of-life issue for a lot of women. I'm 55, and a lot of my female friends and family have gone through menopause in recent years, and are dealing with hormone-related health stuff left and right. So I post this for the interest of our female FReepers and those who live with 'em and love 'em.
1 posted on 08/29/2007 10:43:36 PM PDT by dayglored
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To: dayglored

Oh great. This is what I get to look forward to now.

I better warn my husband. LOL.

Well, maybe I’ll suffer only half-dementia, as I did go back on the estrogen within the last year.


2 posted on 08/29/2007 10:52:12 PM PDT by Shelayne (I will continue to pray for President Bush and my country, as I am commanded to do by my Lord.)
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To: Shelayne
> Oh great. This is what I get to look forward to now.

Sorry about that, Chief.

> I better warn my husband. LOL.

That's only fair...

> Well, maybe I’ll suffer only half-dementia, as I did go back on the estrogen within the last year.

It seems like a tricky tightrope to walk -- as they describe it, the same actions and treatments produce very different results at different ages that are not that far apart, statistically. Best of luck!!

3 posted on 08/29/2007 10:58:37 PM PDT by dayglored (Listen, strange women lying in ponds distributing swords is no basis for a system of government!)
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To: dayglored
Ovaries produce estrogen. Rocca said the likeliest explanation of the study results is that removing ovaries causes a sudden deficiency of that hormone, which in turn affects the brain...

Deep.

Ovaries produce progesterone as well, and progesterone has "protective" effects on the brain. More detail and I'll loose the WAPO audience.

4 posted on 08/29/2007 11:02:44 PM PDT by Rudder
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To: Rudder
> ...Ovaries produce progesterone as well, and progesterone has "protective" effects on the brain...

I get the feeling it's a pretty complicated system that we only vaguely understand.

Or maybe it's just that -I- only vaguely understand it.

Being a testosterone-based life-form, I'm pleased to report that -my- hormones and gonads have little or no effect on my brain. Oh, wait, let me rephrase that...

5 posted on 08/29/2007 11:09:20 PM PDT by dayglored (Listen, strange women lying in ponds distributing swords is no basis for a system of government!)
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To: dayglored
Being a testosterone-based life-form, I'm pleased to report that -my- hormones and gonads have little or no effect on my brain. Oh, wait, let me rephrase that...

NOOOO, your hormones don't have any effect, they just control your brain.

6 posted on 08/29/2007 11:32:01 PM PDT by notpoliticallycorewrecked (California : home of the fruits, nuts and flakes.)
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To: dayglored

Very interesting.

My mother had a complete hysterectomy at about 40. Mild dementia for a couple of decades, and severe for the last lustrum.

It would be nice to think I might escape it due only to genetics as BOTH my parents have suffered with it.

Thanks for posting.


7 posted on 08/29/2007 11:32:21 PM PDT by LegendHasIt
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To: LegendHasIt

So, when does this dementia kick in? I had a hysto almost 30 years ago. I need an excuse....!


8 posted on 08/30/2007 12:18:43 AM PDT by blu (All grammar and punctuation rules are *OFF* for the "24" thread.)
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To: blu

Well, could be just coincidence.... but it took her about 40 years for it to be really noticeable. Probably won’t work as a good excuse for you. ;-)


9 posted on 08/30/2007 12:39:57 AM PDT by LegendHasIt
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To: dayglored

With two jobs, a drained bank account, hot flashes and a cycle that rivals Jurassic Park, I’m lining up for both a hysto AND dementia. Sounds great. I can’t get pregnant AND I won’t care about the bills.


10 posted on 08/30/2007 12:42:24 AM PDT by Hi Heels (Cleverly disguised as a responsible adult)
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To: dayglored

Well this helps explain my ex-wife.LOL


11 posted on 08/30/2007 12:48:38 AM PDT by diverteach
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To: dayglored
I'm going to forego the too-easy jokes about estrogen and dementia, because this really is a serious health and quality-of-life issue for a lot of women

Well if YOU'RE going to forego the too-easy jokes, SOMEbody has to step up to the plate and make one:
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12 posted on 08/30/2007 4:28:07 AM PDT by mkjessup (Jan 20, 2009 - "We Don't Know. Where Rudy Went. Just Glad He's Not. The President. Burma Shave.")
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To: Hi Heels

Best surgery I ever had...mine was 10 years ago I’m now 59...I was put on the estrogen patch...pills, and shots were tried..the gastro intestinal (acid reflux and constipation to the point the bowel shuts down) side effects were to much for me..so I’ve been off the hormones 9 yeas and not major problems except some dryness. No mood swings, few hot flashes any more. I have a long history of reacting badly to meds.


13 posted on 08/30/2007 4:33:53 AM PDT by GailA (I'm proud to admit I'm a quilt-aholic....Run Fred Run!)
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To: dayglored

I haven’t noticed any appreciable dementia in any of my patients over 50 years old that had ovariohysterectomies at less than one year of age.


14 posted on 08/30/2007 4:55:47 AM PDT by vetvetdoug
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To: vetvetdoug

Can any of these patients tell you their phone number?


15 posted on 08/30/2007 5:24:21 AM PDT by Rudder
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To: dayglored
From the people who brought you....

Breast cancer decline attributed to drop in HRT

16 posted on 08/30/2007 5:27:28 AM PDT by mewzilla (Property must be secured or liberty cannot exist. John Adams)
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To: vetvetdoug; dayglored
I haven’t noticed any appreciable dementia in any of my patients over 50 years old that had ovariohysterectomies at less than one year of age.

How many of your patients ever reach 50?

17 posted on 08/30/2007 6:22:56 AM PDT by Paleo Conservative
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To: Paleo Conservative
How many of your patients ever reach 50?

None.....

18 posted on 08/30/2007 6:35:20 AM PDT by vetvetdoug
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To: vetvetdoug
How many of your patients ever reach 50?

None.....

Not even when counting in "doggy" years? ;^) Let's see, last time I heard anything about the conversion of human years into dog years the figure was 1 human year would equal 7 dog years. Do they still use that as a measuring device? Using that equasion my terrier mix is close to 42 years old...wish I'd had his energy back when I was 42.

19 posted on 08/30/2007 6:52:10 AM PDT by Sally'sConcerns (http://www.fda.gov/emaillist.html - Class I (life threatening) recalls email alert sign-up)
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To: diverteach
Well this helps explain my ex-wife.

Might explain Hillary too
20 posted on 08/30/2007 10:33:15 AM PDT by G8 Diplomat (TERM LIMITS! NOW!)
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