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Scientists Transplant Genome of Bacteria
NY Times ^ | June 29, 2007 | NICHOLAS WADE

Posted on 06/29/2007 9:53:49 PM PDT by neverdem

Scientists at the institute directed by J. Craig Venter, a pioneer in sequencing the human genome, are reporting that they have successfully transplanted the genome of one species of bacteria into another, an achievement they see as a major step toward creating synthetic forms of life.

Other scientists who did not participate in the research praised the achievement, published yesterday on the Web site of the journal Science. But some expressed skepticism that it was as significant as Dr. Venter said.

His goal is to make cells that might take carbon dioxide out of the atmosphere and produce methane, used as a feedstock for other fuels. Such an achievement might reduce dependency on fossil fuels and strike a blow at global warming.

“We look forward to having the first fuels from synthetic biology certainly within the decade and possibly in half that time,” he said.

Richard Ebright, a molecular biologist at Rutgers University, said the transplantation technique, which leads to the transferred genome’s taking over the host cell, was “a landmark accomplishment.”

“It represents the complete reprogramming of an organism using only a chemical entity,” Dr. Ebright said.

Leroy Hood, a pioneer of the closely related field of systems biology, said Dr. Venter’s report was “a really marvelous kind of technical feat” but just one of a long series of steps required before synthetic chromosomes could be put to use in living cells.

“It’s a really worthy accomplishment, but I hope it doesn’t get hyped to be more than it is,” Dr. Hood said.

One reason for Dr. Venter’s optimism is that he says his institute is close to synthesizing from simple chemicals an entire genome, 580,000 DNA units in length, of a small bacterium, Mycoplasma genitalium. If that genome can be made to take over a bacterium using the...

(Excerpt) Read more at nytimes.com ...


TOPICS: Business/Economy; Culture/Society; News/Current Events
KEYWORDS: deoxyribonucleicacid; dna; geneticengineering; science
Genome Transplantation in Bacteria: Changing One Species to Another


1 posted on 06/29/2007 9:53:50 PM PDT by neverdem
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To: neverdem
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2 posted on 06/29/2007 9:56:46 PM PDT by martin_fierro (< |:)~)
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To: neverdem

Human/Animal chimeras are coming. Soon.

How are our “bio-ethicists” going to deal with that problem?


3 posted on 06/29/2007 10:00:31 PM PDT by gridlock (Quack ... (thump) Quack ... (thump) Quack ... (thump) Quack ... (thump)......)
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To: neverdem

Mycoplasma genitalium.

The species with the smallest genome size in this class is Mycoplasma genitalium (580 kb), which was originally isolated from urethral specimens of patients with non-gonoccocal urethritis and has since been shown to exist in parasitic association with ciliated epithelial cells of primate genital and respiratory tracts .
http://www.tigr.org/tdb/CMR/gmg/htmls/Background.html

what was that 15 or so years ago about the “simian green monkey”?


4 posted on 06/29/2007 10:10:19 PM PDT by Vn_survivor_67-68
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To: neverdem

This is great! Bacteria that convert a comparatively weak greenhouse gas (CO2) into a much stronger greenhouse gas (CH4) methane.


5 posted on 06/30/2007 12:16:09 AM PDT by Mogollon
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