Posted on 10/16/2006 10:03:23 AM PDT by presidio9
The federal government is moving aggressively to create the first national banking system for umbilical cord blood, which contains the same potentially lifesaving stem cells as bone marrow but with a distinct advantage.
They don't require that the donor and recipient share the same group of genes essential to getting a transplant to take. As a result, they are less likely to be rejected by the recipient.
"We can find donors for everyone. When I say everyone, upward of 90 percent," Dr. John Wagner said.
The number sounds comforting, but it masks a harsh reality. Wagner can screen 6 million people worldwide in search of a perfect bone marrow match for one of his leukemia patients. Yet, finding that match is often impossible.
"Sixty percent, if not more, can't go on because they can't find a donor," said Wagner, who works at the University of Minnesota Cancer Center.
Nevertheless, prospects may improve in coming years for the 15,000 blood cancer patients each year who can't find suitable transplants.
Last year, the Institute of Medicine took note of the promise of cord blood in a report that called for more federal funding to increase supply and to make it easier for doctors to find the best match for their patients.
The federal government is taking steps to fulfill those recommendations.
The Health Resources and Services Administration recently awarded contracts totaling nearly $10 million to coordinate cord blood donations and to monitor the outcome of transplants.
And, any day now, the agency will award about $14 million to public cord blood banks around the country. The goal: Increase the supply of cord blood donations from 50,000 to 150,000.
The increased supply is particularly important for minority patients. Most bone marrow donors are white, so bone marrow donations mostly help white recipients.
"The problem has been lack of access, lack of diverse specimens and just a gross lack of capacity," said Rep. Chris Smith, R-N.J., who co-sponsored the legislation that authorized the funding. "The utilization rates for cord blood are going to skyrocket."
The New York Blood Center is one of the public banks competing for the money. The center has perhaps the largest collection of cord blood units in the world about 35,000 units. Most of the nearly two dozen public banks rely on private donations to operate.
"In our case, since we've built up such a large inventory, it's just about break-even," said Dr. Robert Jones, the center's president.
But, for smaller cord blood banks, it's often tougher to make ends meet, he said.
"Now, they'll have the dollars to get started or to expand their inventory," he said.
Jones said that processing a unit of cord blood costs between $1,000 and $2,000, depending on how it is collected and stored, and the location of the bank itself. The federal funding won't pay the full collection cost, but the subsidy should be enough to substantially expand the cord blood supply, Jones said.
Jones doesn't anticipate that collecting thousands of new donations will pose a problem. Many women would be glad to donate their child's umbilical cord to a public bank, but have no way of doing so. Their opportunity for donation will surely expand as new banks open and others expand. His company, for example, has three new hospitals coming online as collection points in the next year.
Overall, Congress authorized spending up to $15 million a year on cord blood collections over the next four years. An additional $19 million has already been appropriated.
Besides expanding collections, the government will fund the development of an information center for cord blood donations. The center will allow doctors to make one phone call to find the best match for a patient, regardless of where in the country the blood is stored. That money was awarded last month to the National Marrow Donor Program in Minneapolis.
Also, the Medical College of Wisconsin won a contract worth more than $6 million to analyze the outcomes of blood stem cell transplants.
"For us to understand how good cord blood is compared to marrow, we need to have a central data base that collects data on every one, every marrow recipient, every cord blood recipient," Wagner said. "This will allow us to really understand how well cord blood works for every individual type of disease, for every different population of patients."
Wagner, who served on the medical team that performed the first cord blood transplant in the world for a leukemia patient, said scientists are just now learning about the potential benefits of cord blood stem cells.
So far, only about 8,000 cord blood transplants have been performed worldwide, he estimated, but that number is growing quickly. Scientists are also learning new ways to use the cord blood stem cells. For instance, doctors are combining cord blood units to allow for the treatment of adults. Primarily, cord blood transplants have been reserved for children because the amount of stem cells in a single donation isn't enough to help an adult, he said.
Also, scientists are moving beyond using cord blood merely as a way to rescue the bone marrow. Wagner said that scientists have isolated cord blood stem cells that can kill leukemia. Now, they're testing those cells in the treatment of other diseases, such as diabetes and lupus.
"We now find all these novel uses that are just now being explored," Wagner said. "It will take more time for us to prove how effective they are, but there are very unusual types of cells in cord blood that make us particularly excited about it as a new source of cells for many more types of therapy than we ever imagined in the past."
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Umbilical cords?? Don`t they use those things to make sausages?
Assuming what is written is true, then I really don't have a problem with it as the govm't is controlling other individual items such as SSNs, etc. I really don't think there would be much of a market for umbilical cords that anyone could harvest, IMHO.
You know what I want to know -- if the "stuff" in that cord is so vital, wouldn't it make MORE sense to give it to the child to which it actually belongs (i.e. the newborn)?
Just seems like it's taking something from someone who can't consent to it being taken. The placenta and cord is made up of the baby's blood and DNA.
*shrug*
I see both sides -- the advantages are astounding. Historically though, midwives let the cord stay attached to the newborn until it stops pulsing -- as in all the blood meant for the baby is in the baby (and I believe this is the "cord blood" that is referred to).
Just have to wonder what the consequences might be. Or perhaps what they've already been as a result of unnecessary medical intervention in birth (and yes, I DO know there is PLENTY of necessary medical intervention - having had twins via c-section. I'm referring ONLY to unnecessary intervention in normal, healthy situations).
No thanks (clamping).
http://www.cordclamp.com/
http://www.cordclamp.com/HyperbaricLect-2.htm
Don't all good little liberaltarians support embryonic stem-cell research?
lol, perhaps you are a bit uninformed about what libertarians believe in.... I think most of us believe government should not be funding research at all - embyronic or not.
My son was born in Dec 2001. My husband had a brother who died from Leukemia at age 6 and the doctor suggested banking the cord from our son for future need becasue it was an obvious exact match for his stem cells. We did and it is very inexpensive. It initially cost under $200 and it is $50 a year thereafter.
Tom Cruise eats 'em...
Hmmm...your comment just turned my stomach for two reasons:
1. My sister-in-law just gave birth to a baby boy this morning (their 4th kid!), and
2. I was planning on grilling some brats for dinner tonight (thats brats is in bratwurst, not brats as in little rug-rats!)
I may have to rethink that now! LOL
Well, they can have mine but it's 57 years old and kind of gnarly. (Now, where'd I put the damn thing?)
I swear I looked back at my post twice, and I failed to see where I said anything about government funding. I was talking about the current ban on embryonic stem cell research. It extends into the private sector donchaknow, and liberaltarians are against it.
Step one: Cut umbilical chord....
Step Two: Stuff umbilical chord with cat food...
Step 3: Cook it...
Step four: Serve and enjoy!
If it is worth so much money, why do they not pay the donor or give them a credit for medical care?
The ban doesn't block private funding of it, which is why I infered you were speaking of public funding.
You know what happens when you assume, don't you? People who care about human life are against ALL embryonic stem cell research. Funding has nothing to do with it.
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