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Licorice Ingredient Ferrets Out Herpes
Science News Magazine ^ | 5-5-2005 | Nathan Seppa

Posted on 05/05/2005 8:47:59 AM PDT by blam

Licorice ingredient ferrets out herpes

Nathan Seppa

A compound in licorice homes in on lab-grown cells infected with a herpes virus and induces them to self-destruct, a new study finds. These results suggest that a drug based on the compound could seek and destroy herpes viruses hiding in people's bodies. Current antiherpes drugs attack the virus only when it's causing symptoms.

The virus in the new study is Kaposi's sarcoma-associated herpesvirus (KSHV), which causes skin and lymph cancers. The researchers suspect that the gene responsible for KSHV's capacity to hide out is latency-associated nuclear antigen (LANA).

Researchers at New York University ran lab tests on white blood cells, some of which were infected with the herpes virus. Exposing the infected cells to the licorice ingredient, glycyrrhizic acid, shuts down LANA. That starts a chain reaction of biochemical changes in the white blood cells, leading to their suicide and the virus' death. The uninfected cells showed no detrimental effects from glycyrrhizic acid, the researchers report in the March Journal of Clinical Investigation.

Despite these results, simply eating licorice is unlikely to purge a herpes virus from a person's system, says study coauthor Ornella Flore. Most of the glycyrrhizic acid in licorice is probably degraded in a person's stomach, she says.

To develop a treatment, Flore suggests, researchers could inject glycyrrhizic acid into animals previously infected with viruses and determine which viruses it can ferret out, how potent the drug is, and—if the results are promising—what dose would be needed in people.


TOPICS: News/Current Events
KEYWORDS: ferrets; health; herpes; ingredient; licorice; out; virus
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1 posted on 05/05/2005 8:47:59 AM PDT by blam
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To: blam

Katie Holms cold sore ping!


2 posted on 05/05/2005 8:50:15 AM PDT by Perdogg (Rumsfeld for President - 2008)
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To: blam
Note to self: Avoid women who smell like licorice.
3 posted on 05/05/2005 8:50:23 AM PDT by Psycho_Bunny (“I know a great deal about the Middle East because I’ve been raising Arabian horses" Patrick Swazey)
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To: blam

Licorice, Ferrets, and Herpes.


There are 3 words you don't see connected very often.


4 posted on 05/05/2005 8:50:27 AM PDT by cripplecreek (I don't suffer from stress. I am a carrier!)
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To: blam

More good news for the Clintons.


5 posted on 05/05/2005 8:50:40 AM PDT by A Balrog of Morgoth (With fire, sword, and stinging whip I drive the Rats in terror before me.)
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To: blam

Herpes BUMP LOL


6 posted on 05/05/2005 8:51:09 AM PDT by DainBramage
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To: blam

I'm glad I don't have herpes.

I hate licorice.


7 posted on 05/05/2005 8:51:40 AM PDT by nuffsenuff
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To: blam

8 posted on 05/05/2005 8:53:15 AM PDT by Paradox ("It is well that war is so terrible, lest we grow too fond of it."- Robert E. Lee)
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To: blam

I'd be interested to see whether this acid works on other virii. At the very least, it should revolutionize the cold-sore prevention industry.


9 posted on 05/05/2005 8:53:39 AM PDT by Little Pig (Is it time for "Cowboys and Muslims" yet?)
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To: blam
Kiss me I'm safe!!!!!!
- Red Licorice Treat

10 posted on 05/05/2005 8:54:39 AM PDT by Slicksadick (Go out on a limb........Its where the fruit is.)
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To: A Balrog of Morgoth

"More good news for the Clintons."

Now that is funny!


11 posted on 05/05/2005 8:54:45 AM PDT by Old Grumpy
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To: Paradox
Herpes hunter. Image Hosted by ImageShack.us
12 posted on 05/05/2005 8:55:47 AM PDT by cripplecreek (I don't suffer from stress. I am a carrier!)
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To: blam

This is fairly good news as far as I am concerned. Not all Herpes viruses are caused by sexual contact. Herpes Zoster which unfortunately I fall prey to a couple of times a year is from the chicken pox virus, which can lay dormant in the body for 20, 30 years or more and then reappear. I happen to be afflicted with an unusual form of the virus...Herpes Zoster Otitis, which attacks only my left ear approximately every six months or so.....It is not a pleasant thing when it occurs.......I am sure you don't want to know the details or symptoms..


13 posted on 05/05/2005 8:57:30 AM PDT by jsh3180
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To: Paradox
How adorable! Makes me want to run right out and buy one of these...


14 posted on 05/05/2005 8:58:35 AM PDT by Graymatter
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To: blam; Constitution Day; aculeus; general_re; Happygal; BlueLancer; hellinahandcart; Tijeras_Slim; ..
.
I closed my eyes, and when I opened them again the rat was dead and the ratman was slipping the money into his pocket and spitting to clear his mouth.

“That’s what they makes likcerish out of,” he said. “Rat’s blood is what the big factories and the chocolate-people use to make lickerish.”

Again the relish, the wet-lipped, lip-smacking relish as he spoke the words, the throaty richness of his voice and the thick syrupy way he pronounced the word lickerish.

“No,” he said, “There’s nothin wrong with a drop of rat’s blood.”

“Don’t talk so absolutely disgusting,” Claud told him.

“Ah! But that’s it, you see. You eaten it many a time. Penny sticks and lickerish bootlaces is all made from rat’s blood.”

“We don’t want to hear about it, thank you.”

“Boiled up, it is, in great cauldrons, bubblin and steamin and men stirrin it with long poles. That’s one of the big secrets of the chocolate-makin factories, and no one knows about it -- no one except the ratters supplyin the stuff.”

.
-- Roald Dahl, The Ratcatcher.


15 posted on 05/05/2005 9:01:08 AM PDT by dighton
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To: A Balrog of Morgoth

Good news for Robin Williams.


16 posted on 05/05/2005 9:03:45 AM PDT by Eric in the Ozarks
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To: judithann

I was wondering if this ingredient may work on other viruses?


17 posted on 05/05/2005 9:05:43 AM PDT by blam
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To: blam

Note to investors: BUY TWIZZLERS STOCK NOW!


18 posted on 05/05/2005 9:14:30 AM PDT by MisterRepublican
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To: jsh3180

For 26 years I have taken 250 mg. each of BHT and BHA daily. Both are food preservatives on the GRAS list. My objective is life extension (works great on lab rats). However, a side benefit is that these fat soluble substances also modify the fatty surface of various viruses thus allowing the immune system to recognize and attack them. Before I began this regimen I had serious problems with a couple of viruses. No symptoms for 26 years. If I am still here in 30 years I will conclude that the life extension experiment was also successful.


19 posted on 05/05/2005 9:22:10 AM PDT by darth
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To: jsh3180
I sympathise with you. I get those lovely little white cankers on my gums every couple of months, and every two or three years, I have a flare up of Mono which will leave me wiped out for three to four weeks. I recently found out that Mono (like chicken pox) is in the herpes family and it will lie dormant in the body for a period of time before reappearing. It's never been as bad as the first time I had it in tenth grade, but its never fun, and the time it takes to feel human again is frustrating.

I like licorice, maybe I'll start snacking on it more.

20 posted on 05/05/2005 9:26:15 AM PDT by RepoGirl (You can ban my rottweiler when you can pry her from my cold dead hands...)
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