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Human Gland Probably Evolved From Gills
King's College London via ScienceDaily ^ | 2004-12-07 | Anonymous

Posted on 12/21/2004 4:13:57 PM PST by beavus

The human parathyroid gland, which regulates the level of calcium in the blood, probably evolved from the gills of fish, according to researchers from King's College London.

Writing in the latest edition of Proceedings of the National Academy of Sciences, Professor Anthony Graham and Dr Masataka Okabe suggest that the gills of ancestral marine creatures, which were used to regulate calcium levels, were internalised rather than lost when land-living, four-limbed animals – the tetrapods – evolved.

Many physiological processes such as muscle contraction, blood coagulation and signalling by nerve cells, require specific levels of calcium in the body. In humans, calcium levels are regulated by the parathyroid gland, which secretes parathyroid hormone if the calcium concentration in the blood falls too low. This hormone then causes the release of calcium from bone, and increases its reuptake in the kidney, raising the calcium levels back to normal.

Fish don't have parathyroid glands. Instead they increase their internal calcium concentration by using their gills to take up calcium from the surrounding water.

'As the tetrapod parathyroid gland and the gills of fish both contribute to the regulation of extracellular calcium levels, it is reasonable to suggest that the parathyroid gland evolved from a transformation of the gills when animals made the transition from the aquatic to the terrestrial environment,' said Professor Graham.

'This interpretation would also explain why the parathyroid gland is positioned in the neck. If the gland had emerged from scratch when tetrapods evolved it could, as an endocrine organ, have been placed anywhere in the body and still exert its effect.'

The researchers supported their theory by carrying out experiments that show that the parathyroid glands of mice and chickens and the gills of zebrafish and dogfish contain many similarities.

Both gills and parathyroid gland develop from the same type of tissue in the embryo, called the pharyngeal pouch endoderm; both structures express a gene called Gcm-2, and both need this gene to develop correctly.

Furthermore, the researchers found a gene for parathyroid hormone in fish, and they discovered that this gene is expressed in the gills.

'The parathyroid gland and the gills of fish are related structures and likely share a common evolutionary history,' said Professor Graham. 'Our work will have great resonance to all those people who have seen Haeckels' pictures, which show that we all go through a fish stage in our development. This new research suggests that in fact, our gills are still sitting in our throats – disguised as our parathyroid glands.'


TOPICS: Miscellaneous
KEYWORDS: crevolist; kooks; nuttiness; ohsure; please; wierdscience
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To: beavus

Okay, I'll play. My spleen is a remnant of the air bladder. Thats why I can live without if I get in a car accident.


161 posted on 12/21/2004 9:35:08 PM PST by Nachoman
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To: Jim Robinson

God created reusable code. That's an excellent way to describe what seems to have happened.

Faith and reason should not conflict.


162 posted on 12/21/2004 9:43:10 PM PST by DaGman
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To: RightWhale
Will one day our brains evolve into something useful in a higher creature?

Naw. We will make one on a tiny chip of silicon. :-)

163 posted on 12/21/2004 9:45:44 PM PST by RadioAstronomer
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To: beavus

yec intrep


164 posted on 12/21/2004 10:32:35 PM PST by LiteKeeper (Secularization of America is happening)
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To: F16Fighter; buffyt
First they tell me ameeeeeebas

Then apes.....

Most recently gills?????

And now BANANAS??????

So I guess we are slimeeey hairy and....sheeeeesh never mind.
165 posted on 12/21/2004 11:55:46 PM PST by fivekid ( STOP THE WORLD!!!!! I wanna get off.........)
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To: Gondring
I have to constantly remind myself and others of this when talking to laymen, who might take the shorthand literally.

I understand the shorthand but I really believe it goes deeper than just the shorthand and reflects the reality of the thought process. Isn't this shorthand just too heavily relied upon because the thought that it implies is imbedded in the process?

166 posted on 12/22/2004 12:52:26 AM PST by Bellflower (A NEW DAY IS COMING!)
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To: Jorge
My you have a short memory. Let me remind you of your words, very insulting to Christ:

Thank you from and x-evolutionist. I am embarassed to say I once believed this sort of nonsense. Until Christ turned the light on for me!

I don't think I'm stretching here to say that you are accusing Him of being a poofist. And poofism IS absurd.

167 posted on 12/22/2004 3:23:15 AM PST by beavus
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To: shubi

I think the chicken/egg question is valid.
To believe their system, an evolutionist must have every bit as much faith as the creationist does in his, I think.
I'm really not here to try to convince anyone anything, but it is a fun debate.


168 posted on 12/22/2004 3:26:11 AM PST by somemoreequalthanothers
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To: Polybius

I understand the process you are explaining.

It has nothing to do with my big picture, which is that humans would not evolve or exist without a parental oversight already in place.


169 posted on 12/22/2004 3:29:08 AM PST by somemoreequalthanothers
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To: Jorge
You the one characterizing Christ of "believing or professing absurdities" and in your previous post accused Him of being a "deceiver".

I of course did no such thing. I merely characterized your description of Him.

And you post this inflamatory nonsense simply because my stated beliefs in Christ don't agree with your positions on evolution.

What's good for the goose. You have no trouble arrogating His name for your own views at the expense of others, but oh boy, if someone else does the same...

There is a word for that.

170 posted on 12/22/2004 3:29:51 AM PST by beavus
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To: Jorge
Read what your great "father" of evolution believed;

Is your whole LIFE motivated by fallacies? The facts of nature have nothing to do with what anyone, including Darwin, did or did not say.

171 posted on 12/22/2004 3:36:14 AM PST by beavus
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To: Gondring
The question was why it wouldn't evolve to NOT fit.

No, the creationist's point wasn't that sensible. It really was what I said.

172 posted on 12/22/2004 3:38:26 AM PST by beavus
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To: Gondring
Because the deer would survive, and then could reproduce and pass on its genes. Seems self-evident to me.

Deer would survive better if they evolved to fit into the lions mouth? Oooooookay.

173 posted on 12/22/2004 3:39:46 AM PST by beavus
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To: Gondring

that's old cheek and throat pouches originally holding a bubble of air


174 posted on 12/22/2004 3:44:33 AM PST by chemainus
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To: RightWhale

no...you are evolving into a computer and robotics...notice robots smarter that you and I at their task, needing no food or water or shelter or clothing are exploring Mars for you...this is the future of the human race


175 posted on 12/22/2004 3:46:02 AM PST by chemainus
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To: Culture_Values_Morality

no you and apes came from a common ancestor...we all come from fish ( and earlier creatures to be fair)...want to get a surprise ? run your tongue high up your cheek ( on the inside idiot!! *hehehe*) in the direction of your cheekbone...feel the little flaps ar notches ? thise are your vestigial gills....


sorry but now you know we are from slime (-;


176 posted on 12/22/2004 3:48:46 AM PST by chemainus
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To: Abcdefg
I don't think so.

Wow, what an elegant argument.
177 posted on 12/22/2004 3:49:27 AM PST by clyde asbury (Khan, I'm laughing at the superior intellect.)
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To: Bellflower
I wondered what internalised meant until I realized he meant internalized.

Post 101? I can't find the word "internalised". Did you intend to comment on the "I Dream of Jeannie" hypothesis of human development?

It's funny how evos seem to think that creatures change through some kind of will of their own. I really think that you have to read this into their thought processes.

I can't speak for what all people think, but evolutionary biologists know that isn't true. However, there is no shortage of confused lay thinking about evolutionary theory, and even the language of biologists is misleading in its causality (as you say). The closest to the truth your description reads is that creatures' behavior affects their survival, but that is not a useful trait in describing which creatures survive to reproduce, since the trait is essentially ubiquitous.

178 posted on 12/22/2004 3:49:39 AM PST by beavus
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To: F16Fighter

only in my dreams !!!!


( research is in biochemistry; maybe we can brew up something to help with the dreams)


179 posted on 12/22/2004 3:49:45 AM PST by chemainus
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To: Bellflower
Is there food in the womb? No, they receive nutrients from the same place they receive air through there [sic] mothers [sic] blood.

No sh*t.
180 posted on 12/22/2004 3:53:36 AM PST by clyde asbury (Khan, I'm laughing at the superior intellect.)
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