Our farthest flying spacecraft uses solar panels for power. As it gets farther away from our sun, there is less energy available as the distance from our sun increases.
To reach nearest solar system for us, the spacecraft will need to derive energy from the nearest sun. However the gap between the 2 suns is so great that the spacecraft simply dies from entering the vast dark space between the two suns. If we can’t even send a spacecraft to the nearest solar system, forget about ever reaching much farther away solar systems and their planets to discover life.
This assumes we would only have solar arrays, and not arrays powered by high-energy particles other than photons from the sun.