My wife was diagnosed with MM in Jan 2020 and went through all of the standard treatments, all of which eventually became ineffective. The cancer ravaged her body, breaking all her long bones (arms and legs), damaging her kidneys to the brink of needing dialysis, etc.
Earlier this year she started on the bi-specific antibodies. The cancer markers (blood tests) took a dive, almost unbelievable response.
However the side effects have been horrific. CRS, ICANS, weakness, fatigue, respiratory trouble, gastrointestinal trouble, headaches, terrible unstoppable cough. It got bad enough she insisted on stopping the treatment, and switch to just monitoring the cancer markers going forward.
So this treatment is fantastic at what it does to the cancer. But when they say in the article: “...serious side effects were common in both groups...” they sure ain’t kidding.