Posted on 12/21/2025 9:00:14 PM PST by ConservativeMind
A blood biomarker yet to be used in cardiac arrest care can give a clearer picture of the extent of brain damage after a cardiac arrest. This has been shown in a large international multicenter study.
A simple blood test that can very accurately predict the chance of survival with good recovery will be of great significance for patients in intensive care after a cardiac arrest.
This assertion comes from the researchers behind a large multicenter study in which four brain damage biomarkers in the blood were compared to ascertain how reliably they could estimate the extent of brain damage among unconscious patients after cardiac arrest.
The results show that the two brain biomarkers routinely used in care for different types of brain damage—neuron-specific enolase and S-100 protein—have significant limitations regarding the prognosis assessment for brain damage after cardiac arrest.
The study confirms previous preliminary results by comparing four biomarkers using an analysis method that can be applied in clinical settings.
"We saw that the biomarker neurofilament light, NFL, correctly identifies 92% of all patient outcomes at six months after the cardiac arrest," says Marion Moseby Knappe.
Neurofilament light is already used as a brain biomarker, for example in the care of patients with the neurological disease, MS. Another of the biomarkers in the study—GFAP—was better at estimating the extent of brain damage than those in current clinical use.
"NFL was superior to the other three biomarkers. It's better at differentiating between patients with major and minor brain damage, and can also give an answer as quickly as 24 hours after the cardiac arrest. The biomarker is also more stable in the blood, which is significant in the measurement process," says Moseby Knappe.
(Excerpt) Read more at medicalxpress.com ...
Fine, but what if you’re dead?
You’re told to eat kale.
Bkmk
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