Even with seasonal fruit, our ancestors would have gotten very little fructose until the advent of agriculture, and even then since fruit couldn’t be stored for long, only locally or in small expensive quantities in cities. The exception being conversion to alcohol, like wine. Our metabolism needs glucose, so the constant conversion of high amounts of fructose to glucose sets up a bunch of hormonal imbalances.
Dried fruit is probably one of the first foods we learned to process to store long term.