Exposure to trihalomethanes linked to chronic kidney disease (Water filtration helps)

Medical Xpress / HealthDay / JAMA Network Open ^ | July 9, 2025 | Elana Gotkine / Danielle N. Medgyesi et al / Simon John Christoph Soerensen et al

[ConservativeMind]

Exposure to trihalomethanes—especially brominated trihalomethanes—in residential community water supplies (CWS) is associated with an increased risk of chronic kidney disease (CKD), according to a study published online July 2.

Danielle N. Medgyesi, Ph.D. and colleagues conducted a prospective cohort study to examine long-term exposure to trihalomethanes in residential CWS and its association with CKD risk using data from the California Teachers Study, including female teachers and administrators enrolled between 1995 and 1996 with data linked to mortality and health care records.

The study sample included 89,320 female participants with 6,242 cases of CKD. The researchers observed a clear exposure-response association between trihalomethanes and CKD risk in flexible spline-based models, with the highest risk seen for brominated trihalomethanes.

For brominated trihalomethanes in the highest two exposure categories, the hazard ratios for CKD risk were 1.23 and 1.43, respectively. The largest contributor to the association of the overall mixture with CKD risk was brominated trihalomethanes, followed by uranium, arsenic, and chloroform (52.9%, 35.4%, 6.2%, and 5.5%, respectively).

"These findings are supported by substantial experimental evidence and carry important public health implications given the widespread use of water chlorination and the growing global burden of CKD," the authors write.

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TOPICS: Health/Medicine
KEYWORDS: kidneydisease; trihalomethanes

[ConservativeMind]

Most of these are drastically reduced by catalytic carbon filtration. Activated carbon is no better than 50% as good, and maybe be 1/5 as good, on some elements.

Arsenic is better addressed by ion-exchange or reverse osmosis. Catalytic carbon appears to reduce arsenic by over 50%. I wouldn’t rely on activated carbon for much arsenic reduction.

[ConservativeMind]

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[Does so]

Known for decades.

Is there a link to cancer via bromilated trihalomethanes from home swimming pools?

[sauropod]

Bkmk