Posted on 04/15/2025 8:39:15 PM PDT by ConservativeMind
Great. I take Vitamin C supplement and have had three MRIs done in the past two years.
More information on Vit C - also what form - Ascorbic Acid, Calcium Ascorbate, Liposomal, etc.
Reading the article now. Thank you.
Checking on Vitamin C and chelation because never heard of gadolinium. If body is attempting to get rid of foreign heavy metals by chelation, then it is trying to get rid of same gadolinium.
Persons taking Vitamin C may also be taking Magnesium, of which the most common form is Magnesium Oxide because it is the cheapest to produce and purchase.
Wonder what relation this may have to Oxalate issue named in article.
Magnesium OXIDE. = OXALATE issue with MRI and gadolinium?
have you had contrast used with the MRI in any of the three? That is the key, gadolinium contrast (the only type used with MRI). The oxalate pulls the contents out of the contrast.
I’ve been trying to tell people for a while that vitamin C supplements (most are junk) are linked to stone formation, not vitamin D supplements or calcium supplements per se.
Mayo has 24 hour urine test for this . It is expensive. You will need to have symptoms to get insurance to pay.
Hell, I’ve probably had 20 such Gadolinium shots. Never paid attention to diet. Never had a problem (that I know of..).
I had a problem. Do not remember if I was taking C but definitely wasn’t taking the other
All I know is I had an MRI with contrast gadolinium and had to squeeze the ball to be let out of the machine due to allergic reaction. I started feeling a sensation every time it did a revolution felt like there was something on either side of my face being pulled out of my skin. Turned out I was growing hives there and down my back.
There is pre treatment and after treatment for that if you need one again
I know I had contrast in at least one and maybe two.
Wow, nasty reaction! Did the hives resolve ok?
I felt a momentary hot flush when the contrast was injected and that was it.
Conclusions: Total and supplemental intake of vitamin C was significantly associated with a higher risk of incident kidney stones in men, but not among women.
A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism
Mn-PyC3A is a newly developed manganese-based MR imaging contrast agent that produces comparable MR angiographic contrast enhancement to the commercially available gadolinium-based contrast agent gadopentetate dimeglumine....
Conclusion
Mn-PyC3A enables contrast-enhanced MR angiography with comparable contrast enhancement to gadolinium-based agents and may overcome concerns regarding gadolinium-associated toxicity and retention.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5831267/
My brother in law is a radiologist, board certified in nuclear medicine, specializing in cancer treatment. He owns several MRI machines and we had a conversation recently about the new contrasting agents available to replace gadolinium. It looks promising.
Ferumoxytol:
Off-label use:
While not specifically FDA-approved for MRI contrast, ferumoxytol (Feraheme) has been used off-label for MR angiography, showing promising results with reduced dosage and a good safety profile.
Advantages:
Ferumoxytol offers advantages like extended imaging windows, higher MRI time efficiency, and no nephrotoxicity, making it a potential alternative to gadolinium-based agents, according to an article from Oxford Academic.
Safety:
It has a reassuring safety profile when used within the recommended dose range for diagnostic imaging, according to the National Institutes of Health (NIH).
Manganese-based agents:
Mn-PyC3A:
This manganese-based agent has shown contrast enhancement comparable to gadolinium-based agents in contrast-enhanced MR angiography, according to the National Institutes of Health (NIH).
Potential benefits:
Manganese-based agents could potentially address concerns about gadolinium deposition and toxicity, according to the National Institutes of Health (NIH).
Elucirem (Gadopiclenol):
Newer GBCA:
While still gadolinium-based, Elucirem (Vueway) was a notable addition in 2022, approved by the FDA, and is designed to deliver high-quality brain and body lesion visualization at half the conventional gadolinium dose, according to an article from Applied Radiology.
Lower dosing:
This lower dosing is in line with recommendations from health agencies and radiology associations to reduce gadolinium exposure.
Emerging technologies:
Research is ongoing in areas like Organic Radical Contrast Agents (ORCAs), which utilize nitroxides to enhance MRI contrast.
Sodium ascorbate and liposomal vitamin C. If I had something serious I would stay “C” saturated all day long. Liposomal C will do this.
Sodium ascorbate will replicate this saturation but you must take third of a teaspoon every 2 hours. You have heard of intravenous vitamin C. Sodium ascorbate is used for this.
I’ve had kidney stones. So now I have to choose between kidney stones and scurvy? The pirate’s dilemma.
I had a CTscan yesterday (no dye) and told the VA technician of my own previous experience with the contrast dye rushing to my crotch. Now my penis has about a inch and a half long section turned to stone. I mentioned the article about warming the dye first before injection and she said she hopes to convince the boss to buy a contrast dye warmer after my experience. She told me about density which I thought was amusing since I had been a mass properties expert in the past.
CM, thanks for posting this, for any future MRIs I have.
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