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To: Oystir

Actually, they do, but normal nicotinamide riboside does not cross well.

Liposome-based loading enhances the distribution of nicotinamide riboside chloride into the brain and its neuroprotective effects in cerebral ischemic mice

https://www.sciencedirect.com/science/article/pii/S2324242624000184

NMN crosses:

Nicotinamide Mononucleotide Adenylyltransferase 1 Regulates Cerebral Ischemia–Induced Blood–Brain Barrier Disruption Through NAD+/SIRT1 Signaling Pathway

https://link.springer.com/article/10.1007/s12035-022-02903-6


9 posted on 04/01/2025 4:32:56 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I don’t believe the NAD compounds you mention are available over the counter. They certainly are not the ones that are even mentioned in cosmetics, let alone pills, which are totally merit less.


10 posted on 04/01/2025 4:53:29 PM PDT by Oystir ( )
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