Anatomic lung resection linked to improved survival for early-stage lung cancer

Medical Xpress / 2025 Society of Thoracic Surgeons Annual Meeting ^ | Jan. 27, 2025 | Christopher Seder, MD et al

[ConservativeMind]

New research presented at the 2025 Society of Thoracic Surgeons (STS) Annual Meeting reveals that anatomic lung resections, such as lobectomy and segmentectomy, are associated with improved long-term survival compared to wedge resection for patients with early-stage non-small cell lung cancer (NSCLC).

The study analyzed outcomes for more than 32,000 stage 1A NSCLC patients using data from the STS General Thoracic Surgery Database (STS GTSD) with long-term follow-up linked to the National Death Index and Centers for Medicare and Medicaid Services database, which provides up to 10 years of survival data.

Lobectomy for stage 1A NSCLC offered the highest survival rates, with a five-year overall survival (OS) of 71.9% and 10-year OS of 44.8%. Segmentectomy, which resulted in a five-year OS of 69.6% and 10-year OS of 44.2% proved to be a viable alternative. Both lobectomy and segmentectomy demonstrated better outcomes than wedge resection, which had five-year OS of 66.3% and 10-year OS of 41.4%.

This research highlights the profound effect of using real-world data to provide critical insights that complement findings from randomized controlled trials (RCTs). While RCTs suggest an equivalence between lobectomy and sub-lobar resections, this real-world study gives clinicians additional insight. It provides a broader perspective applicable to diverse patient populations and health care settings.

"This study reinforces the need for nuanced decision-making, integrating both RCTs and real-world data to deliver the highest quality of care," said Christopher Seder, MD. "By analyzing outcomes in a variety of health care settings, we can offer informed recommendations, ultimately improving patient outcomes across the board."

[ConservativeMind]

“Lobectomy and segmentectomy are associated with improved long-term survival compared to wedge resection for patients with early-stage non-small cell lung cancer (NSCLC).”

You have better choices available for this.

[ConservativeMind]

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[Bob434]

i caught pneumonia one year awhile back, got over it but had several spots on the lung- Docs said it was cancer, explaiend that pneumonia can trigger it i guess- anyway, they were gonna do a lobectomy on me, and i was one week away from the date, and got nervous, and asked for a biopsy to make sure it was cancer first- They agreed to do so- took several biopsies, and not a sign of cancer-

They called off the surgery, but never could tell me what the spots were- the doc even said ‘it could be tuberculosis, but unlikely’- That made me feel better lol-

anyway- still have all me lungs- spots disappeared within several months- still no idea what they were-

[irishjuggler]

Knew a lady, ~60-year cigarette smoker, who had a lung-cancer lobectomy around 74... lived another 20 years to 94.

[tired&retired]

I had a left lung lobotomy last year due to a cancer mass bigger than a golf ball.

They no longer open the chest cavity from the front.

They now put an inch and a half incision in your back and have a special tool they insert with a camera to remove the lung and staple the bronchial tubes, pulminary artery and vein off with titanium staples.

It’s called VATS, or video assisted thoracic surgery. I was out of the hospital in two days with no medications or restrictions.

[tired&retired]

LOL... darn spellchecker check changed lobectomy to lobotomy

😁😁😔

[ConservativeMind]

I am glad you could get such minimal surgery for a concern like that.

Keyhole surgery is amazing.