[ConservativeMind]

Vitamin K3, known as menadione, is normally used in animal feed, but it is also used in humans in places like India, according to Wikipedia. Yes, it is available, here.

“The typical daily dose is 10 mg oral or 2 mg parenteral.” — Wikipedia

It seems to work because it causes oxidation, which is not something we normally seek, and is what anti-oxidants try to quench.

[ConservativeMind]

The Wikipedia entry:

https://en.m.wikipedia.org/wiki/Menadione

[ConservativeMind]

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[where's_the_Outrage?]

Imagine if someone asks what is your job title, and you reply “I’m a mouse proctologist.”

Just like you dreamed about becoming as kid.

[linMcHlp]

From the article:

When mice with prostate cancer are given menadione, it messes with the cancer's survival processes. Trotman's team has discovered that menadione kills prostate cancer cells by depleting a lipid called PI(3)P, which works like an ID tag. Without it, the cells stop recycling incoming materials and eventually explode.

[know.your.why]

Oh good. My mouse will be so relieved.

[steve86]

Menadione is converted to vitamin K2 in the body. I wonder if taking K2 (which I do) has the same outcome or if the precursor form is needed.

[fwdude]

I’m glad to be done with my sir-ograms (prostate check.) Had mine removed 5 years ago and have just had my 5-year PSA checked. Undetectable PSA. Had a great surgeon.

[fwdude]

My question is, how do they “give” prostate cancer to lab mice?